5-Nitropyridine-2-carboxylic acid

Product Name: 5-Nitropyridine-2-carboxylic acid
CAS No.: 30651-24-2
Chemical Name: 5-Nitropyridine-2-carboxylic acid
Synonyms: 5-Nitro-2-picoL;5-Nitropicolinicaci;5-NITROPICOLINIC ACID;5-NITRO-2-PICOLINIC ACID;5-NITRO-2-PYRIDINECARBOXYLIC ACID;5-NITROPYRIDINE-2-CARBOXYLIC ACID;3-NITRO-6-PYRIDINE CARBOXYLIC ACID;2-PYRIDINECARBOXYLIC ACID, 5-NITRO-;5-Nitropyridine-2-carboxylicacid98%;5-NITROPYRIDINE-2-CARBOXYLIC ACID 98%
CBNumber: CB0240808
Molecular Formula: C6H4N2O4
Formula Weight: 168.11
MOL File: 30651-24-2.mol

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5-Nitropyridine-2-carboxylic acid Property

Melting point:: 218-220°C
Boiling point:: 389.8±27.0 °C(Predicted)
Density: 1.570±0.06 g/cm3(Predicted)
storage temp.: Inert atmosphere,2-8°C
solubility: Soluble in dimethyl sulfoxide.
form: Solid
pka: 2.71±0.13(Predicted)
color: Light Yellow
InChI: InChI=1S/C6H4N2O4/c9-6(10)5-2-1-4(3-7-5)8(11)12/h1-3H,(H,9,10)
InChIKey: QKYRCTVBMNXTBT-UHFFFAOYSA-N
SMILES: C1(C(O)=O)=NC=C([N+]([O-])=O)C=C1
CAS DataBase Reference: 30651-24-2(CAS DataBase Reference)
NIST Chemistry Reference: Picolinic acid, 5-nitro-(30651-24-2)

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Safety

Hazard Codes: Xn
Risk Statements: 22-20/21/22
Safety Statements: 24/25-36/37
HS Code: 29333990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: N0930
Product name: 5-Nitro-2-pyridinecarboxylic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $83
Updated: 2025/07/31

TCI Chemical

Product number: N0930
Product name: 5-Nitro-2-pyridinecarboxylic Acid
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $248
Updated: 2025/07/31

TRC

Product number: N518250
Product name: 5-Nitro-2-picolinicAcid
Packaging: 500mg
Price: $45
Updated: 2021/12/16

ChemScene

Product number: CS-W008569
Product name: 5-Nitro-2-pyridinecarboxylic Acid
Purity: 99.80%
Packaging: 10g
Price: $52
Updated: 2021/12/16

Apolloscientific

Product number: OR52054
Product name: 5-Nitropyridine-2-carboxylicacid
Purity: 98%
Packaging: 5g
Price: $60
Updated: 2021/12/16

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5-Nitropyridine-2-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

Light Yellow Solid

Uses

It plays an important role in synthetic intermediate.

Uses

5-Nitropyridine-2-carboxylic acid is a useful synthetic intermediate.

Synthesis

4487-59-6

30651-24-2

General procedure for the synthesis of 5-nitro-2-pyridinecarboxylic acid from 2-bromo-5-nitropyridine: this method is based on the procedure reported by Oehlke, J.; Schroetter, E.; Dove, S.; Schick, H.; Niedrich, H. in Pharmazie 1983,38,591-596, with slight modifications. When N,N-dimethylformamide (DMF) was used instead of dimethylsulfoxide (DMSO) as solvent for the reaction with 2-bromo-5-nitropyridine and copper(I) cyanide, a subsequent hydrolysis step afforded the target product 5-nitro-2-pyridinecarboxylic acid in 70% yield. This product is usually used directly in subsequent reactions without further purification.

References

[1] Patent: WO2004/14904, 2004, A1. Location in patent: Page 53
[2] Pharmazie, 1983, vol. 38, # 9, p. 591 - 596
[3] Hoppe-Seyler's Zeitschrift fuer Physiologische Chemie, 1951, vol. 288, p. 237,241
[4] Patent: WO2009/141386, 2009, A1. Location in patent: Page/Page column 89

5-Nitropyridine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Toluene Sodium Chromium(VI) oxide Diethyl malonate 2-Chloro-5-nitropyridine Sulfuric acid

Preparation Products

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5-Nitropyridine-2-carboxylic acid Suppliers

Americas 1 Canada 1 China 178 Europe 1 Germany 4 India 5 Japan 1 Switzerland 1 United Kingdom 7 United States 33 Global 232

Jiangyin Jufeng Biotechnology Co., Ltd

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Accela ChemBio Co.,Ltd.

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View Lastest Price from 5-Nitropyridine-2-carboxylic acid manufacturers

PNP Biotech Co. Ltd

Product: 5-Nitro-2-pyridinecarboxylic acid 30651-24-2
Price: US $0.00/kg
Min. Order: 25kg
Purity: 98%
Supply Ability: Inquiry
Release date: 2023-07-13

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 5-Nitropicolinic acid 30651-24-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10KG
Release date: 2021-11-26

Hong Kong Tiansheng New Material Trading Co., Ltd

Product: 5-Nitropyridine-2-carboxylic acid 30651-24-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 0.99
Supply Ability: 100KG
Release date: 2022-01-14

30651-24-2, 5-Nitropyridine-2-carboxylic acidRelated Search:

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30651-24-2

Acids and Derivatives

Heterocycles

Building Blocks

Chemical Synthesis

Carboxylic Acids

Pyridines

Aromatics Compounds

Aromatics

Carboxylic Acids

Heterocycle-Pyridine series

Heterocyclic Building Blocks

New Products for Chemical Synthesis

C6