ChemicalBook > CAS DataBase List > 2,5-Thiophenedicarboxylic acid

2,5-Thiophenedicarboxylic acid

Product Name: 2,5-Thiophenedicarboxylic acid
CAS No.: 4282-31-9
Chemical Name: 2,5-Thiophenedicarboxylic acid
Synonyms: THIOPHENE-2,5-DICARBOXYLIC ACID;TH-2COOH;RARECHEM AL BE 0623;2,5-Thiophenedicarbo;OTAVA-BB BB7013911425;2,5-DICARBOXYTHIOPHENE;2,5-THIOPHENEDICARBOXYLIC;thiophene-2,5-dicarboxylate;Thiophene-2,5-Dicarboxyl Acid;2,5-THIOPHENEDICARBOXYLIC ACID
CBNumber: CB9224515
Molecular Formula: C6H4O4S
Formula Weight: 172.16
MOL File: 4282-31-9.mol

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2,5-Thiophenedicarboxylic acid Property

Melting point:: >300 °C (lit.)
Boiling point:: 272.46°C (rough estimate)
Density: 1.473 (estimate)
refractive index: 1.5500 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
form: solid
pka: 2.76±0.10(Predicted)
color: White to Light yellow
Water Solubility: Very soluble in water.
BRN: 136781
InChI: InChI=1S/C6H4O4S/c7-5(8)3-1-2-4(11-3)6(9)10/h1-2H,(H,7,8)(H,9,10)
InChIKey: YCGAZNXXGKTASZ-UHFFFAOYSA-N
SMILES: C1(C(O)=O)SC(C(O)=O)=CC=1
CAS DataBase Reference: 4282-31-9(CAS DataBase Reference)
EPA Substance Registry System: 2,5-Thiophenedicarboxylic acid (4282-31-9)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36-37/39
WGK Germany: 3
TSCA: Yes
HazardClass: IRRITANT
HS Code: 29349990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 405191
Product name: 2,5-Thiophenedicarboxylic acid
Purity: 99%
Packaging: 5g
Price: $18.76
Updated: 2025/07/31

Sigma-Aldrich

Product number: 405191
Product name: 2,5-Thiophenedicarboxylic acid
Purity: 99%
Packaging: 25g
Price: $37.5
Updated: 2025/07/31

TCI Chemical

Product number: T2347
Product name: 2,5-Thiophenedicarboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $41
Updated: 2025/07/31

TCI Chemical

Product number: T2347
Product name: 2,5-Thiophenedicarboxylic Acid
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $125
Updated: 2025/07/31

TRC

Product number: D431270
Product name: 2,5-Dicarboxythiophene
Packaging: 1g
Price: $45
Updated: 2021/12/16

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2,5-Thiophenedicarboxylic acid Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Uses

2,5-Thiophenedicarboxylic acid may be used as a thiophene based linker in the preparation of magnesium coordination networks. It may also be used as a precursor in the synthesis of 2,5-bis-benzoxazoyl-thiophene (EBF).
It may be used in the synthesis of the following:

new cobalt(II) thiophenedicarboxylate coordination polymer
novel mesogenic thiophene based supramolecular liquid crystals
two novel coordination polymers with the formula {[Ln₂(2,5-tdc)₃(dmso)₂]H₂O}_n (Ln = Tb(III) and Dy(III)), (2,5-tdc² = 2,5-thiophenedicarboxylate and dmso = dimethylsulfoxide)

Synthesis Reference(s)

Journal of the American Chemical Society, 72, p. 2109, 1950 DOI: 10.1021/ja01161a065

General Description

2,5-Thiophenedicarboxylic acid (2,5-TDCA, H₂TDC) is an important building block in the preparation of fluorescent brightening agent, fungicides and anti-cancer drug. It has been generated by chlorination of adipic acid using thionyl chloride. Due to its diverse coordination modes, it is an excellent choice as an aromatic linker to generate coordination networks. The enthalpies of combustion and sublimation of 2,5-thiophenedicarboxylic acid have been evaluated by rotary-bomb combustion calorimetry.

2,5-Thiophenedicarboxylic acid Preparation Products And Raw materials

Raw materials

Adipic acid Sodium sulfide nonahydrate Sodium sulfide Chlorobenzene Thionyl chloride

Preparation Products

2,5-Bis(5-tert-butyl-2-benzoxazolyl)thiophene

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View Lastest Price from 2,5-Thiophenedicarboxylic acid manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 2,5-Thiophenedicarboxylic acid 4282-31-9
Price: US $65.00-20.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-04

Henan Aochuang Chemical Co.,Ltd.

Product: 2,5-Thiophenedicarboxylic acid 4282-31-9
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-19

Hebei Yanxi Chemical Co., Ltd.

Product: 2,5-Thiophenedicarboxylic acid 4282-31-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2023-09-14

4282-31-9, 2,5-Thiophenedicarboxylic acidRelated Search:

OXALIC ACID Dibenzothiophene Thiophene 2,5-PYRIDINEDICARBOXYLIC ACID EPA Cephalothin sodium Tetrahydrothiophene Thifensulfuron Thiophene-3-ethanol 2-Thiophenecarboxylic acid Thiophene-2,3-dicarboxylicacid Ascoric Acid 2-Thiophenecarboxaldehyde THIOPHEN-3-YLMETHYL-AMMONIUM CHLORIDE COPPER(I) THIOPHENE-2-CARBOXYLATE Thiophene-2,5-dicarbonitrile 2-Thiopheneacetic acid THIENO[3,2-B]PYRIDINE

2,5-Thiophenedicarbo

Thiophene -2,5- twocarboxylic acid

2,5-Thiophenedicarboxylic Acid, 97+%

2,5-Thiophenedicarboxylic acid 99%

2,5-Thiophenedicarboxylic acid,96%

TH-2COOH

2,5-DICARBOXYTHIOPHENE

2,5-THIOPHENEDICARBOXYLIC ACID

RARECHEM AL BE 0623

OTAVA-BB BB7013911425

THIOPHENE-2,5-DICARBOXYLIC ACID

Thiophene-2,5-Dicarboxyl Acid

Thiophene-2,5-dicarboxylicacid,97%

2,5-THIOPHENEDICARBOXYLIC

Thiophene-,'-dicarboxylic acid

2,5-Thiophenedicarboxylic Acid,>98%

2,5-Thiophenedicarboxylic acid ISO 9001：2015 REACH

thiophene-2,5-dicarboxylate

2,5-Thiophenedicarboxylic Acid (OB Acid)

2,5-dicarboxylic acid thiophene OB acid

4282-31-9

4292-31-9

CH4O4S

C6H2O4S

C6H4O4S

C4H2SCOOH2

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Thiophenes

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Reagents for Conducting Polymer Research

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Thiophen

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