N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE

ChemicalBook > CAS DataBase List > N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE

N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE

Description

Product Name: N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
CAS No.: 78538-74-6
Chemical Name: N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
Synonyms: LSU-65;FG 7142;Zk-31906;ZK 39106;β-CCA methylamide;FG 7142, 10 mM in DMSO;N-Methyl-β-carboline-3-carboxamide;N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE;B-carboline-3-carboxylic acid N-*methylamide;4-b)indole-3-carboxamide,n-methyl-9h-pyrido(
CBNumber: CB9228957
Molecular Formula: C13H11N3O
Formula Weight: 225.25
MOL File: 78538-74-6.mol

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N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Property

Boiling point:: 576.3±30.0 °C(Predicted)
Density: 1.328±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: ethanol: 1 mg/mL
pka: 13.44±0.46(Predicted)
form: A crystalline solid
color: light tan

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Safety

WGK Germany: 3
RTECS: UU9780100

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: E006
Product name: β-Carboline-3-carboxylic acid N-methylamide
Packaging: 100mg
Price: $282
Updated: 2024/03/01

Sigma-Aldrich

Product number: E006
Product name: β-Carboline-3-carboxylic acid N-methylamide
Packaging: 500mg
Price: $974
Updated: 2024/03/01

Cayman Chemical

Product number: 29183
Product name: FG-7142
Purity: ≥98%
Packaging: 50mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 29183
Product name: FG-7142
Purity: ≥98%
Packaging: 100mg
Price: $153
Updated: 2024/03/01

Cayman Chemical

Product number: 29183
Product name: FG-7142
Packaging: 10mg
Price: $59
Updated: 2021/12/16

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N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Chemical Properties,Usage,Production

Description

FG 7142 (ZK 39106; LSU-65) is a nonselective benzodiazepine inverse agonist with high affinity (Ki= 91 nM) for the α1 subunit-containing GABAA receptor. FG 7142 also modulates GABA-induced chloride flux (EC50=137 nM) at GABAA receptors expressing the α1 subunit. FG 7142 increases tyrosine hydroxylation and leads to upregulation of β-adrenergic receptors in mouse cerebral cortex.

Uses

FG 7142 is a benzodiazepine inverse agonist anxiogenic compound.

Definition

ChEBI: N-methyl-9H-pyrido[3,4-b]indole-3-carboxamide is a member of beta-carbolines.

Biological Activity

Inverse agonist and anxiogenic agent. Increases tyrosine hydroxylation and causes upregulation of β -adrenoceptors in mouse cerebral cortex.

Biochem/physiol Actions

Benzodiazepine inverse receptor agonist; potent anxiogenic agent.

storage

Store at RT

N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Suppliers

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78538-74-6, N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDERelated Search:

Deionized water (2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE 9H-PYRIDO[3,4-B]INDOLE ZERENEX E/6026476 N-(4-CHLOROPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE N-(2,4-DIMETHYLPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE 1-METHYL-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)-9H-BETA-CARBOLINE-3-CARBOXAMIDE 2-([(1-METHYL-9H-BETA-CARBOLIN-3-YL)CARBONYL]AMINO)BENZOIC ACID N-(2,3-DIMETHYLPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE ZERENEX E/6026463 ZERENEX E/6026469 ZERENEX E/6026461 1-METHYL-N-(2-METHYLPHENYL)-9H-BETA-CARBOLINE-3-CARBOXAMIDE N-(2,5-DIMETHYLPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE ZERENEX E/6026467 ZERENEX E/6026471

4-b)indole-3-carboxamide,n-methyl-9h-pyrido(

n-methyl-9h-pyrido(3,4-b)indole-3-carboxamide

FG 7142

N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE

B-carboline-3-carboxylic acid N-*methylamide

N-METHYL-B-CARBOLINE-3-CARBOXAMIDE (FG-7 142)

beta-carboline-3-carboxylic acid N-methylamide

β-Carboline-3-carboxylic acid N-methylamide

β-CCA methylamide, FG-7142, N-Methyl-β-carboline-3-carboxamide

9H-Pyrido(3,4-B)indole-3-carboxamide, N-methyl-

Zk-31906

β-CCA methylamide

9H-beta-Carboline-3-carboxylic acid methylamide

LSU-65

ZK 39106

N-Methyl-β-carboline-3-carboxamide

ZK39106,nucleus accumben,inverse agonist,GABA Receptor,LSU65,LSU 65,dopaminergic,FG 7142,GABAA receptor,inhibit,FG-7142,Gamma-aminobutyric acid Receptor,ZK-39106,FG7142,tyrosine hydroxylase,γ-Aminobutyric acid Receptor,Inhibitor

FG 7142, 10 mM in DMSO

78538-74-6

GABA/Glycine receptor