ChemicalBook > CAS DataBase List > N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
Description- Product Name
- N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
- CAS No.
- 78538-74-6
- Chemical Name
- N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
- Synonyms
- LSU-65;FG 7142;Zk-31906;ZK 39106;β-CCA methylamide;N-Methyl-β-carboline-3-carboxamide;N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE;B-carboline-3-carboxylic acid N-*methylamide;4-b)indole-3-carboxamide,n-methyl-9h-pyrido(;n-methyl-9h-pyrido(3,4-b)indole-3-carboxamide
- CBNumber
- CB9228957
- Molecular Formula
- C13H11N3O
- Formula Weight
- 225.25
- MOL File
- 78538-74-6.mol
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N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Property
- Boiling point:
- 576.3±30.0 °C(Predicted)
- Density
- 1.328±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- ethanol: 1 mg/mL
- pka
- 13.44±0.46(Predicted)
- form
- A crystalline solid
- color
- light tan
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Safety
- WGK Germany
- 3
- RTECS
- UU9780100
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- E006
- Product name
- β-Carboline-3-carboxylic acid N-methylamide
- Packaging
- 100mg
- Price
- $282
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- E006
- Product name
- β-Carboline-3-carboxylic acid N-methylamide
- Packaging
- 500mg
- Price
- $974
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29183
- Product name
- FG-7142
- Purity
- ≥98%
- Packaging
- 50mg
- Price
- $93
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29183
- Product name
- FG-7142
- Purity
- ≥98%
- Packaging
- 100mg
- Price
- $153
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 29183
- Product name
- FG-7142
- Packaging
- 10mg
- Price
- $59
- Updated
- 2021/12/16
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N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Chemical Properties,Usage,Production
Description
FG 7142 (ZK 39106; LSU-65) is a nonselective benzodiazepine inverse agonist with high affinity (Ki= 91 nM) for the α1 subunit-containing GABAA receptor. FG 7142 also modulates GABA-induced chloride flux (EC50=137 nM) at GABAA receptors expressing the α1 subunit. FG 7142 increases tyrosine hydroxylation and leads to upregulation of β-adrenergic receptors in mouse cerebral cortex.
Uses
FG 7142 is a benzodiazepine inverse agonist anxiogenic compound.
Definition
ChEBI: N-methyl-9H-pyrido[3,4-b]indole-3-carboxamide is a member of beta-carbolines.
Biological Activity
Inverse agonist and anxiogenic agent. Increases tyrosine hydroxylation and causes upregulation of β -adrenoceptors in mouse cerebral cortex.
Biochem/physiol Actions
Benzodiazepine inverse receptor agonist; potent anxiogenic agent.
storage
Store at RT
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
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N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE Suppliers
- Tel
- --
- Fax
- --
- info-tech@nacalai.co.jp
- Country
- Japan
- ProdList
- 6046
- Advantage
- 75
78538-74-6, N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDERelated Search:
Deionized water
(2R,3S/2S,3R)-3-(4-Chloro-5-fluoro-6-pyrimidinyl)-2-(2,4-difluorophenyl)butan-2-ol hydrochloride
N-METHYL-BETA-CARBOLINE-3-CARBOXAMIDE
9H-PYRIDO[3,4-B]INDOLE
ZERENEX E/6026476
N-(4-CHLOROPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE
N-(2,4-DIMETHYLPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE
1-METHYL-N-(5-PHENYL-1,3,4-THIADIAZOL-2-YL)-9H-BETA-CARBOLINE-3-CARBOXAMIDE
2-([(1-METHYL-9H-BETA-CARBOLIN-3-YL)CARBONYL]AMINO)BENZOIC ACID
N-(2,3-DIMETHYLPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE
ZERENEX E/6026463
ZERENEX E/6026469
ZERENEX E/6026461
1-METHYL-N-(2-METHYLPHENYL)-9H-BETA-CARBOLINE-3-CARBOXAMIDE
N-(2,5-DIMETHYLPHENYL)-1-METHYL-9H-BETA-CARBOLINE-3-CARBOXAMIDE
ZERENEX E/6026467
ZERENEX E/6026471