Methyl 2,5-Dibromopentanoate
- Product Name
- Methyl 2,5-Dibromopentanoate
- CAS No.
- 50995-48-7
- Chemical Name
- Methyl 2,5-Dibromopentanoate
- Synonyms
- METHYL 2,5-DIBROMOVALERATE;METHYL 2,5-DIBROMOPENTANOATE;2,5-Dibromovaleric acid methyl ester;2,5-Dibromopentanoic acid methyl ester;Pentanoic acid, 2,5-dibromo-, methyl ester
- CBNumber
- CB9231007
- Molecular Formula
- C6H10Br2O2
- Formula Weight
- 273.95
- MOL File
- 50995-48-7.mol
Methyl 2,5-Dibromopentanoate Property
- Boiling point:
- 93-95°C 1mm
- Density
- 1,746 g/cm3
- storage temp.
- 2-8°C
- solubility
- Chloroform (Slightly, Sonicated), Methanol (Slightly)
- form
- Oil
- color
- Colourless
- InChI
- InChI=1S/C6H10Br2O2/c1-10-6(9)5(8)3-2-4-7/h5H,2-4H2,1H3
- InChIKey
- YVHCGWPKBSEBTH-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)C(Br)CCCBr
Safety
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HS Code
- 2915705090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- M301180
- Product name
- Methyl2,5-Dibromopentanoate
- Packaging
- 500mg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- OR8857
- Product name
- Methyl2,5-dibromopentanoate
- Packaging
- 1g
- Price
- $56
- Updated
- 2021/12/16
- Product number
- FD55468
- Product name
- 2,5-Dibromopentanoic acid methyl ester
- Packaging
- 500mg
- Price
- $60
- Updated
- 2021/12/16
- Product number
- 2123-9-X1
- Product name
- Methyl 2,5-dibromopentanoate
- Packaging
- 1g
- Price
- $61
- Updated
- 2021/12/16
- Product number
- FD55468
- Product name
- 2,5-Dibromopentanoic acid methyl ester
- Packaging
- 1g
- Price
- $100
- Updated
- 2021/12/16
Methyl 2,5-Dibromopentanoate Chemical Properties,Usage,Production
Uses
Methyl 2,5-Dibromopentanoate can be used for liquid crystal compounds for display devices.
Synthesis
542-28-9
67-56-1
50995-48-7
The general procedure for the synthesis of methyl 2,5-dibromovalerate from tetrahydro-2H-pyran-2-one and methanol was as follows: 518 g of 6-valerol and 5 ml of phosphorus tribromide were added to an 11-necked, three-necked flask. The mixture was heated to 95 °C to 105 °C under stirring conditions, followed by the slow addition of 550 g of bromine while controlling the reaction temperature between 100 °C and 120 °C. After the reaction system was stabilized, another 5 ml of phosphorus tribromide and 236 g of bromine were added at 110 °C. After the addition was completed, the reaction mixture was allowed to stand for 30 minutes and subsequently cooled to between 0°C and 10°C. Next, 11 ml of methanol and 1 g of p-toluenesulfonic acid were added to the reaction system and the reaction temperature was maintained at 25 °C. After refluxing the reaction mixture for 5 hours, the excess reagent was removed by distillation and the lower organic phase was isolated. The organic phase was washed sequentially with 500 ml of 10% sodium hydroxide solution and 500 ml of water. After the washing was completed, the organic layer was separated and purified by fractional distillation (139 °C to 142 °C/28 hPa) to give 612.7 g of methyl 2,5-dibromopentanoate in 45% yield and >96% GC purity.
References
[1] Chemical Communications, 2015, vol. 51, # 70, p. 13470 - 13473
[2] Patent: WO2005/28449, 2005, A1. Location in patent: Page/Page column 11
[3] Tetrahedron, 1998, vol. 54, # 19, p. 4991 - 5004
Methyl 2,5-Dibromopentanoate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Methyl 2,5-Dibromopentanoate manufacturers
- Product
- Methyl2,5-Dibromopentanoate 50995-48-7
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99.3%
- Supply Ability
- 100 tons
- Release date
- 2022-01-14