ChemicalBook > CAS DataBase List > 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE

1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE

Product Name: 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE
CAS No.: 109384-27-2
Chemical Name: 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE
Synonyms: 1-Methyl-2-piperazinone HCl;1-Methylpiperazin-2-one HCl;1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE;Piperazinone, 1-Methyl-, Monohydrochloride;2-Piperazinone,1-methyl-, hydrochloride (1:1)
CBNumber: CB9234538
Molecular Formula: C5H11ClN2O
Formula Weight: 150.61
MOL File: 109384-27-2.mol

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1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE Property

storage temp.: Inert atmosphere,Room Temperature
Appearance: White to off-white Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

TRC

Product number: M322208
Product name: 1-Methylpiperazin-2-oneHydrochloride
Packaging: 25mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M322208
Product name: 1-Methylpiperazin-2-oneHydrochloride
Packaging: 250mg
Price: $130
Updated: 2021/12/16

AK Scientific

Product number: 1842AA
Product name: 1-Methylpiperazin-2-onehydrochloride
Packaging: 250mg
Price: $104
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H48-5-BC
Product name: 1-Methylpiperazin-2-one hydrochloride
Purity: 97.0%
Packaging: 250mg
Price: $115
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H48-5-BC
Product name: 1-Methylpiperazin-2-one hydrochloride
Purity: 97.0%
Packaging: 1g
Price: $290
Updated: 2021/12/16

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1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE Chemical Properties,Usage,Production

Synthesis

109384-26-1

109384-27-2

The general procedure for the synthesis of 1-methylpiperazin-2-one hydrochloride from tert-butyl 4-methyl-3-oxopiperazine-1-carboxylate was as follows: 4N HCl-dioxane solution (20 mL) was added to tert-butyl 4-methyl-3-oxopiperazine-1-carboxylate (2.06 g) and the reaction mixture was stirred for 1 hour at room temperature. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. Toluene was added to the residue and the solvent was again removed by azeotropic distillation under reduced pressure. The residue was dried to give 1-methylpiperazin-2-one hydrochloride as an oil (1.44 g, 99% yield). The product was characterized by 1H-NMR (400 MHz, DMSO-d6): δ 2.86 (3H, s), 3.34 (2H, br m), 3.50 (2H, m), 3.64 (2H, s). Mass spectra (ESI) showed m/z: 115 ([M + H]+).

References

[1] Patent: EP1621537, 2006, A1. Location in patent: Page/Page column 47
[2] Patent: EP1762568, 2007, A1. Location in patent: Page/Page column 36
[3] Patent: EP1785418, 2007, A1. Location in patent: Page/Page column 43-44
[4] Patent: EP1803719, 2007, A1. Location in patent: Page/Page column 39

1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Ethylenediamine Ethanol Sodium chloride Di-tert-butyl dicarbonate Sodium Tetrahydrofuran Ethyl acetate Sodium hydroxide PETROLEUM ETHER Iodomethane Sulfuric acid Ethyl chloroacetate

Preparation Products

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View Lastest Price from 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE manufacturers

Career Henan Chemical Co

Product: 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE 109384-27-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-12

109384-27-2, 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDERelated Search:

4-Ethyl-2,3-dioxo-1-piperazine carbonyl chloride BUTTPARK 138\40-67 BUTTPARK 138\40-61 BUTTPARK 138\40-57 1-(3-Chloro-4-(diethylamino)benzyl)-4-hexyl-2,3-piperazinedione 1,4-BIS[3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]-3,6-BIS[(DIMETHYLAMINO)METHYLENE]TETRAHYDRO-2,5-PYRAZINEDIONE BUTTPARK 138\40-92 METHYL 7-(4-CHLOROBENZYL)-5,8-DIOXOHEXAHYDRO[1,3]THIAZOLO[3,4-A]PYRAZINE-3-CARBOXYLATE 1-(4-(5-amino-6-chloro-2-pyridyl)aminobenzyl)-4-benzyl-2,3-dioxopiperazine METHYL 7-(2-([3-CHLORO-5-(TRIFLUOROMETHYL)-2-PYRIDINYL]AMINO)ETHYL)-5,8-DIOXOHEXAHYDRO[1,3]THIAZOLO[3,4-A]PYRAZINE-3-CARBOXYLATE BUTTPARK 138\40-64 BUTTPARK 138\40-62 BUTTPARK 138\40-59 BUTTPARK 138\40-27 BUTTPARK 138\40-60 BUTTPARK 107\40-27 BUTTPARK 138\40-68 1-AMINO-4-(3,5-DICHLOROPHENYL)PIPERAZINE-2,5-DIONE

1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE

Piperazinone, 1-Methyl-, Monohydrochloride

1-Methylpiperazin-2-one HCl

2-Piperazinone,1-methyl-, hydrochloride (1:1)

1-Methyl-2-piperazinone HCl

109384-27-2