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1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE

Product Name
1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE
CAS No.
109384-27-2
Chemical Name
1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE
Synonyms
1-Methyl-2-piperazinone HCl;1-Methylpiperazin-2-one HCl;1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE;Piperazinone, 1-Methyl-, Monohydrochloride;2-Piperazinone,1-methyl-, hydrochloride (1:1)
CBNumber
CB9234538
Molecular Formula
C5H11ClN2O
Formula Weight
150.61
MOL File
109384-27-2.mol
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1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE Property

storage temp. 
Inert atmosphere,Room Temperature
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

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N-Bromosuccinimide Price

TRC
Product number
M322208
Product name
1-Methylpiperazin-2-oneHydrochloride
Packaging
25mg
Price
$45
Updated
2021/12/16
TRC
Product number
M322208
Product name
1-Methylpiperazin-2-oneHydrochloride
Packaging
250mg
Price
$130
Updated
2021/12/16
AK Scientific
Product number
1842AA
Product name
1-Methylpiperazin-2-onehydrochloride
Packaging
250mg
Price
$104
Updated
2021/12/16
SynQuest Laboratories
Product number
4H48-5-BC
Product name
1-Methylpiperazin-2-one hydrochloride
Purity
97.0%
Packaging
250mg
Price
$115
Updated
2021/12/16
SynQuest Laboratories
Product number
4H48-5-BC
Product name
1-Methylpiperazin-2-one hydrochloride
Purity
97.0%
Packaging
1g
Price
$290
Updated
2021/12/16
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1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE Chemical Properties,Usage,Production

Synthesis

109384-26-1

109384-27-2

The general procedure for the synthesis of 1-methylpiperazin-2-one hydrochloride from tert-butyl 4-methyl-3-oxopiperazine-1-carboxylate was as follows: 4N HCl-dioxane solution (20 mL) was added to tert-butyl 4-methyl-3-oxopiperazine-1-carboxylate (2.06 g) and the reaction mixture was stirred for 1 hour at room temperature. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure. Toluene was added to the residue and the solvent was again removed by azeotropic distillation under reduced pressure. The residue was dried to give 1-methylpiperazin-2-one hydrochloride as an oil (1.44 g, 99% yield). The product was characterized by 1H-NMR (400 MHz, DMSO-d6): δ 2.86 (3H, s), 3.34 (2H, br m), 3.50 (2H, m), 3.64 (2H, s). Mass spectra (ESI) showed m/z: 115 ([M + H]+).

References

[1] Patent: EP1621537, 2006, A1. Location in patent: Page/Page column 47
[2] Patent: EP1762568, 2007, A1. Location in patent: Page/Page column 36
[3] Patent: EP1785418, 2007, A1. Location in patent: Page/Page column 43-44
[4] Patent: EP1803719, 2007, A1. Location in patent: Page/Page column 39

1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE manufacturers

Career Henan Chemical Co
Product
1-METHYL-PIPERAZIN-2-ONE HYDROCHLORIDE 109384-27-2
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100KG
Release date
2020-02-12