8-HYDROXY-QUINOLINE-5-CARBALDEHYDE

Product Name: 8-HYDROXY-QUINOLINE-5-CARBALDEHYDE
CAS No.: 2598-30-3
Chemical Name: 8-HYDROXY-QUINOLINE-5-CARBALDEHYDE
Synonyms: 5g 1 pcs;IFLAB-BB F2108-0159;Indacaterol Impurity 29;Indacaterol Impurity 22;5-Formyl-8-hydroxyquinoline;8-HYDROXY-QUINOLINE-5-CARBALDEHYDE;8-Hydroxyquinoline-5-carboxaldehyde;8-hydroxy-5-Quinolinecarboxaldehyde;5-Quinolinecarboxaldehyde,8-hydroxy-
CBNumber: CB9243130
Molecular Formula: C10H7NO2
Formula Weight: 173.17
MOL File: 2598-30-3.mol

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8-HYDROXY-QUINOLINE-5-CARBALDEHYDE Property

Melting point:: 178 °C
Boiling point:: 383.1±22.0 °C(Predicted)
Density: 1.364±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Solid
pka: 3.88±0.10(Predicted)
color: Green
InChI: InChI=1S/C10H7NO2/c12-6-7-3-4-9(13)10-8(7)2-1-5-11-10/h1-6,13H
InChIKey: LIADJWREMDHKHQ-UHFFFAOYSA-N
SMILES: N1C2C(=C(C=O)C=CC=2O)C=CC=1

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Safety

Hazard Codes: Xn
Risk Statements: 22-36/37/38
Safety Statements: 26

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS018146
Product name: 8-hydroxy-quinoline-5-carbaldehyde
Purity: Aldrich<SUP>CPR</SUP>
Packaging: 10 mg
Price: $73.1
Updated: 2025/07/31

TRC

Product number: A430530
Product name: 8-Hydroxyquinoline-5-carbaldehyde
Packaging: 100mg
Price: $70
Updated: 2021/12/16

AK Scientific

Product number: 2196AB
Product name: 8-Hydroxyquinoline-5-carbaldehyde
Packaging: 100mg
Price: $97
Updated: 2021/12/16

AK Scientific

Product number: 2196AB
Product name: 8-Hydroxyquinoline-5-carbaldehyde
Packaging: 1g
Price: $286
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0299155
Product name: 8-HYDROXY-QUINOLINE-5-CARBALDEHYDE
Purity: 95.00%
Packaging: 5MG
Price: $505.49
Updated: 2021/12/16

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8-HYDROXY-QUINOLINE-5-CARBALDEHYDE Chemical Properties,Usage,Production

Uses

8-Hydroxyquinoline-5-carbaldehyde is used in preparation of Polycyclic compounds.

Synthesis

148-24-3

67-66-3

2598-30-3

8-Hydroxyquinoline (5 g, 0.034 mol) was dissolved in ethanol (50 mL), followed by the addition of sodium hydroxide (10 g, 0.25 mol) dissolved in water (15 mL). The mixed solution was heated to reflux and trichloromethane was added slowly and dropwise over 30 minutes. After continuing the reflux reaction for 20 h, ethanol and unreacted trichloromethane were removed by distillation under reduced pressure. The residue was dissolved in water (150 mL) and the pH was adjusted to slightly acidic with dilute hydrochloric acid. The resulting yellow solid was extracted with dichloromethane and the extract was purified by column chromatography (silica gel as stationary phase and dichloromethane/methanol as eluent) to give 8-hydroxyquinoline-5-carbaldehyde as a final white solid (115 mg, 0.67 mmol). The structure of the product was confirmed by 1H-NMR (CDCl3, 400 MHz) and 13C-NMR (DMSO-d6, 400 MHz): 1H-NMR δ = 10.16 (s, 1H), 9.71 (dd, 1H, J = 1.6Hz, 8.4Hz), 8.89 (dd, 1H, J = 1.6Hz, 4.0Hz), 8.02 (d , 1H, J = 8.0 Hz), 7.69 (q, 1H, J = 4.0 Hz), 7.30 (d, 1H, J = 8.0 Hz); 13C-NMR δ = 193.1, 160.5, 149.9, 141.1, 138.9, 133.9, 127.7, 125.5, 123.4, 111.7.

References

[1] Journal of Coordination Chemistry, 2012, vol. 65, # 9, p. 1632 - 1644
[2] Journal of Organic Chemistry, 2011, vol. 76, # 10, p. 3774 - 3781
[3] Journal of the Chilean Chemical Society, 2012, vol. 57, # 3, p. 1287 - 1291
[4] Farmaco, 1993, vol. 48, # 5, p. 615 - 636
[5] Gazzetta Chimica Italiana, 1995, vol. 125, # 2, p. 69 - 76

8-HYDROXY-QUINOLINE-5-CARBALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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8-HYDROXY-QUINOLINE-5-CARBALDEHYDE Suppliers

Canada 1 China 84 Germany 1 India 2 United States 5 Global 93

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View Lastest Price from 8-HYDROXY-QUINOLINE-5-CARBALDEHYDE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-Quinolinecarboxaldehyde,8-hydroxy- 2598-30-3
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-07-30

2598-30-3, 8-HYDROXY-QUINOLINE-5-CARBALDEHYDERelated Search:

4-Quinolinecarboxaldehyde, 8-hydroxy- Formaldehyde Copper quinolate 8-Benzyloxy-5-(2-bromoacetyl)-2-hydroxyquinoline 5-ACETYL-8-HYDROXY-1H-QUINOLIN-2-ONE Indacaterol Impurity 3 (S)-Indacaterol Indacaterol Impurity 12 5-ForMyl-8-hydroxycarbostyril 8-Benzyloxy-5-((R)-2-broMo-1-hydroxyethyl)-1H-quinolinone Indacaterol Impurity 34 5-Acetyl-8-(phenylmethoxy)-2-quinolinone 2-Aminoindan hydrochloride 2(1H)-Quinolinone, 8-hydroxy-5-[(1R,2R)-1-hydroxy-2-[(1-methylethyl)amino]butyl]-, rel- 2(1H)-Quinolinone, 5,5'-[[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)imino]bis(1-hydroxy-2,1-ethanediyl)]bis[8-(phenylmethoxy)- 2(1H)-Quinolinone, 5-[(1S)-2-[(5,6-diethyl-2,3-dihydro-1H-inden-2-yl)amino]-1-hydroxyethyl]-8-(phenylmethoxy)- 5,6-Diethyl-2,3-dihydro-1H-inden-2-amine hydrochloride Indacaterol interMediate

IFLAB-BB F2108-0159

8-HYDROXY-QUINOLINE-5-CARBALDEHYDE

5g 1 pcs

5-Quinolinecarboxaldehyde,8-hydroxy-

8-hydroxy-5-Quinolinecarboxaldehyde

8-Hydroxyquinoline-5-carboxaldehyde

Indacaterol Impurity 22

Indacaterol Impurity 29

5-Formyl-8-hydroxyquinoline

2598-30-3