ChemicalBook > CAS DataBase List > PLEVITREXED
PLEVITREXED
- Product Name
- PLEVITREXED
- CAS No.
- 153538-08-0
- Chemical Name
- PLEVITREXED
- Synonyms
- (Rac)-BGC9331;(Rac)-ZD 9331;(Rac)-Plevitrexed;(Rac)Plevitrexed,(Rac) Plevitrexed;2H-Tetrazole-5-butanoic acid, α-[[4-[[(3,4-dihydro-2,7-dimethyl-4-oxo-6-quinazolinyl)methyl]-2-propyn-1-ylamino]-2-fluorobenzoyl]amino]-
- CBNumber
- CB92451263
- Molecular Formula
- C26H25FN8O4
- Formula Weight
- 532.53
- MOL File
- 153538-08-0.mol
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PLEVITREXED Property
- Density
- 1.44±0.1 g/cm3(Predicted)
- pka
- 3.35±0.10(Predicted)
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PLEVITREXED Chemical Properties,Usage,Production
Uses
(Rac)-Plevitrexed ((Rac)-ZD 9331; (Rac)-BGC9331)?is a racemate of Plevitrexed. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor. (Rac)-Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
References
[1] Tochowicz A, et al. Development and binding mode assessment of N-[4-[2-propyn-1-yl[(6S)-4,6,7,8-tetrahydro-2-(hydroxymethyl)-4-oxo-3H-cyclopenta[g]quinazolin-6-yl]amino]benzoyl]-l-γ-glutamyl-D-glutamic acid (BGC 945), a novel thymidylate synthase inhibitor that targets tumor cells. J Med Chem.?2013?Jul 11;56(13):5446-55. DOI:10.1021/jm400490e
PLEVITREXED Preparation Products And Raw materials
Raw materials
Preparation Products
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PLEVITREXED Suppliers
- Tel
- 1-631-485-4226; 16314854226
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- United States
- ProdList
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- +1-781-999-5354; +17819995354
- marketing@targetmol.com
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- United States
- ProdList
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- sales@medchemexpress.com
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- United States
- ProdList
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153538-08-0, PLEVITREXEDRelated Search:
7-METHYLQUINAZOLIN-4(1H)-ONE
PROP-2-YNYL-P-TOLYL-AMINE
4-amino-2-fluoro-N-methylbenzamide
PLEVITREXED