1-PYRAZIN-2-YL-ETHYLAMINE

Product Name: 1-PYRAZIN-2-YL-ETHYLAMINE
CAS No.: 179323-60-5
Chemical Name: 1-PYRAZIN-2-YL-ETHYLAMINE
Synonyms: 1-(Pyrazin-2-yl);1-(2-Pyrazinyl)ethanamine;1-PYRAZIN-2-YL-ETHYLAMINE;1-(Pyrazin-2-yl)ethanamine;1-(pyrazin-2-yl)ethan-1-aMine;2-Pyrazinemethanamine, α-methyl-;alpha-Methyl-2-pyrazinemethanamine;2-Pyrazinemethanamine, .alpha.-methyl-
CBNumber: CB92458631
Molecular Formula: C6H9N3
Formula Weight: 123.16
MOL File: 179323-60-5.mol

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1-PYRAZIN-2-YL-ETHYLAMINE Property

Boiling point:: 215.0±25.0 °C(Predicted)
Density: 1.088±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: 8.19±0.40(Predicted)
Appearance: Colorless to light yellow Liquid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: P840900
Product name: 1-(Pyrazin-2-yl)ethylamine
Packaging: 10g
Price: $1470
Updated: 2021/12/16

AK Scientific

Product number: Z2224
Product name: 1-(Pyrazin-2-yl)ethanamine
Packaging: 5g
Price: $464
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM1048664
Product name: 1-(PYRAZIN-2-YL)ETHYLAMINE
Purity: 95.00%
Packaging: 5MG
Price: $500.65
Updated: 2021/12/16

Matrix Scientific

Product number: 124180
Product name: 1-(Pyrazin-2-yl)ethanamine
Purity: 95+%
Packaging: 1g
Price: $594
Updated: 2021/12/16

AK Scientific

Product number: Z2224
Product name: 1-(Pyrazin-2-yl)ethanamine
Packaging: 25g
Price: $1769
Updated: 2021/12/16

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1-PYRAZIN-2-YL-ETHYLAMINE Chemical Properties,Usage,Production

Uses

1-(Pyrazin-2-yl)ethylamine is a pyrazine derivative and a potential beta3-adrenoceptor agonist.

Synthesis

22047-25-2

179323-60-5

General procedure for the synthesis of 1-(pyrazin-2-yl)ethanamine from 2-acetylpyrazine: preparation of 1-(pyrazin-2-yl)ethanamine; the synthetic method used in this preparation is summarized below. 1-(Pyrazin-2-yl)ethanone (2.0 g, 15.85 mmol) and ammonium acetate (19.337 g, 158.5 mmol) were dissolved in methanol (50 mL). Subsequently, sodium cyanoborohydride (0.7 g, 11.1 mmol) was added all at once. The reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, methanol was removed under reduced pressure, water (20 mL) was added to the residue and the solution was alkalized to pH=13 by addition of sodium hydroxide.The alkalized aqueous solution was extracted with dichloromethane, the organic phases were combined and dried over anhydrous sodium sulfate. Finally, the solvent was removed under reduced pressure to give 14.62 g of 1-(pyrazin-2-yl)ethylamine in 75% yield. Mass spectrometry analysis showed that the (M+H)+ peak was located at 124.

References

[1] Patent: US2009/163502, 2009, A1. Location in patent: Page/Page column 41-42
[2] Patent: US2009/163499, 2009, A1. Location in patent: Page/Page column 29
[3] Patent: US2009/170873, 2009, A1. Location in patent: Page/Page column 43-44
[4] Patent: US2009/170874, 2009, A1. Location in patent: Page/Page column 60
[5] Patent: US2010/152203, 2010, A1. Location in patent: Page/Page column 20

1-PYRAZIN-2-YL-ETHYLAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-PYRAZIN-2-YL-ETHYLAMINE Suppliers

Canada 1 China 54 Germany 1 India 3 Switzerland 1 United States 8 Global 68

J & K SCIENTIFIC LTD.

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Hangzhou Molcore Biopharmatech Co.,Ltd

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View Lastest Price from 1-PYRAZIN-2-YL-ETHYLAMINE manufacturers

Career Henan Chemical Co

Product: 1-PYRAZIN-2-YL-ETHYLAMINE 179323-60-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2019-12-19

179323-60-5, 1-PYRAZIN-2-YL-ETHYLAMINERelated Search:

Pyrazinamide 2-(Methylthio)-5-aminopyridine (5-Ethylisoxazol-3-yl)amine (5-Fluoro-pyridin-2-yl)-Methyl-aMine 6-methoxychroman-4-amine (2-Bromopyridin-4-yl)methanamine hydrochloride AKOS B023083 2-Pyrimidinamine, N-(1-methylethyl)- (9CI)

1-PYRAZIN-2-YL-ETHYLAMINE

1-(Pyrazin-2-yl)ethanamine

2-Pyrazinemethanamine, .alpha.-methyl-

1-(pyrazin-2-yl)ethan-1-aMine

1-(Pyrazin-2-yl)

alpha-Methyl-2-pyrazinemethanamine

1-(2-Pyrazinyl)ethanamine

2-Pyrazinemethanamine, α-methyl-

179323-60-5