HDH-PHARMA 26173

Product Name: HDH-PHARMA 26173
CAS No.: 871836-51-0
Chemical Name: HDH-PHARMA 26173
Synonyms: 4-CHLORO-1H-PYRAZOLO[4,3-C]PYRIDINE;1H-Pyrazolo[4,3-c]pyridine,4-chloro-;100182;EOS-61542;HDH-PHARMA 26173;4-chloro-1H-pyrazolo[4;4-Chloro-1H-pyrazolo[4,3-...;4-chloro-1H-pyrazolo[4,4-c]pyridine;4-Chloro-1H-pyrazolo[4,3-c]pyridine 98%;4-chloro-1H-pyrazolo[4,3-c]pyridin-6-aMine
CBNumber: CB92465688
Molecular Formula: C6H4ClN3
Formula Weight: 153.57
MOL File: 871836-51-0.mol

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HDH-PHARMA 26173 Property

Boiling point:: 357.5±22.0 °C(Predicted)
Density: 1.531
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: solid
pka: 10.46±0.40(Predicted)
Appearance: White to light yellow Solid
InChI: InChI=1S/C6H4ClN3/c7-6-4-3-9-10-5(4)1-2-8-6/h1-3H,(H,9,10)
InChIKey: FUXZQGSDRGDYGX-UHFFFAOYSA-N
SMILES: C1(Cl)=NC=CC2NN=CC1=2

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Safety

WGK Germany: WGK 3
HS Code: 2933399990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: BLN00015
Product name: 4-Chloro-1H-pyrazolo[4,3-c]pyridine
Packaging: 1g
Price: $1160
Updated: 2026/03/19

TRC

Product number: C379330
Product name: 4-Chloro-1H-pyrazolo[4,3-c]pyridine
Packaging: 1g
Price: $165
Updated: 2021/12/16

Matrix Scientific

Product number: 067147
Product name: 4-Chloro-1H-pyrazolo[4,3-c]pyridine
Packaging: 1g
Price: $30
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-5-41
Product name: 4-Chloro-1H-pyrazolo[4,3-c]pyridine
Purity: 95%
Packaging: 1g
Price: $75
Updated: 2021/12/16

AK Scientific

Product number: W8946
Product name: 4-Chloro-1H-pyrazolo[4,3-c]pyridine
Packaging: 1g
Price: $82
Updated: 2021/12/16

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HDH-PHARMA 26173 Chemical Properties,Usage,Production

Uses

4-Chloro-1H-pyrazolo[4,3-c]pyridine is used to prepare gp120-CD4 inhibitors.

Synthesis

134031-24-6

871836-51-0

General procedure for the synthesis of 4-chloro-1H-pyrazolo[4,3-c]pyridine using 2,4-dichloronicotinaldehyde as starting material: intermediate 1 (1.7 g, 9.7 mmol) was dissolved in dimethoxyethane (12 ml) at room temperature, followed by addition of hydrazine monohydrate (1.2 ml, 38.6 mmol). The reaction mixture was stirred at 75°C overnight. Upon completion of the reaction, the mixture was concentrated to dryness and the resulting crude product was purified by fast chromatography using 20% to 100% ethyl acetate/petroleum ether gradient elution to afford the target product, 4-chloro-1H-pyrazolo[4,3-c]pyridine, as a white solid (0.82 g, 56% yield). The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ 7.60 (d, J = 6.9 Hz, 1H), 8.14 (d, J = 6.0 Hz, 1H), 8.32 (s, 1H); mass spectra (ES + APCI)+: m/z 154 [M + H]+.

References

[1] Patent: WO2012/38743, 2012, A1. Location in patent: Page/Page column 82
[2] Patent: WO2010/106333, 2010, A1. Location in patent: Page/Page column 78-79
[3] Patent: WO2016/37578, 2016, A1. Location in patent: Page/Page column 118
[4] Patent: EP2857400, 2015, A1. Location in patent: Paragraph 1032
[5] Patent: WO2015/58084, 2015, A1. Location in patent: Paragraph 0403

HDH-PHARMA 26173 Preparation Products And Raw materials

Raw materials

Preparation Products

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HDH-PHARMA 26173 Suppliers

China 168 India 3 United Kingdom 2 United States 10 Global 183

Shanghai Gugang New Materials Technology Co. Ltd.

Tel: 021-51317962
Fax: 021-51317962
Email: 296935822@qq.com
Country: China
ProdList: 999
Advantage: 58

Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Email: marketing@accelachem.com
Country: China
ProdList: 9711
Advantage: 58

Anhui Shuoyuan Pharmaceutical Technology R&D Co.,Ltd

Tel: 05558228005 18151793555
Email: 413315120@qq.com
Country: China
ProdList: 176
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Beijing HwrkChemical Technology Co., Ltd

Tel: 89508211 18501085097
Fax: 010-89508210
Email: sales.bj@hwrkchemical.com
Country: China
ProdList: 9416
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Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44802
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
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Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7891
Advantage: 64

ZEROSCHEM.CO.,LTD.

Tel: 10-61256048 13810278579
Fax: +86 10 61256049
Email: sales@zeroschem.com
Country: China
ProdList: 1385
Advantage: 59

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070 13913916777
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 16029
Advantage: 64

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View Lastest Price from HDH-PHARMA 26173 manufacturers

Career Henan Chemical Co

Product: HDH-PHARMA 26173 871836-51-0
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 200kg
Release date: 2018-12-21

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100182

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