ChemicalBook > CAS DataBase List > Paquinimod

Paquinimod

Product Name
Paquinimod
CAS No.
248282-01-1
Chemical Name
Paquinimod
Synonyms
ABR25757;ABR 25757;ABR-25757;ABR?215757;Paquinimod;ABR?215757; ABR 215757; ABR215757; PAQUINIMOD.;ABR-25757,Inhibitor,ABR25757,inhibit,Paquinimod;ABR 25757;ABR-25757;ABR25757;PAQUINIMOD;248282-01-1;N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide;N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
CBNumber
CB92498835
Molecular Formula
C21H22N2O3
Formula Weight
350.41
MOL File
248282-01-1.mol
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Paquinimod Property

Boiling point:
487.3±45.0 °C(Predicted)
Density 
1.267±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO:15.0(Max Conc. mg/mL);42.8(Max Conc. mM)
form 
A solid
pka
4.50±1.00(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
28443
Product name
Paquinimod
Packaging
1mg
Price
$55
Updated
2024/03/01
Cayman Chemical
Product number
28443
Product name
Paquinimod
Packaging
25mg
Price
$914
Updated
2024/03/01
Cayman Chemical
Product number
28443
Product name
Paquinimod
Packaging
5mg
Price
$224
Updated
2024/03/01
Cayman Chemical
Product number
28443
Product name
Paquinimod
Packaging
10mg
Price
$420
Updated
2024/03/01
AK Scientific
Product number
1997DM
Product name
Paquinimod
Packaging
5mg
Price
$146
Updated
2021/12/16
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Paquinimod Chemical Properties,Usage,Production

Uses

Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4. Paquinimod reduces pathology in experimental collagenase-induced osteoarthritis. Paquinimod treatment of collagenase-induced OA (CIOA) resulted in significantly reduced synovial thickening (57%), osteophyte size at the medial femur (66%) and cruciate ligaments (67%) and cartilage damage at the medial tibia (47%) and femur (75%; n=7, untreated n=6). Paquinimod reduces leukocyte recruitment during sterile inflammation. Paquinimod also reduced priming of proinflammatory effector CD4(+) T cells.

Paquinimod Preparation Products And Raw materials

Raw materials

Preparation Products

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Paquinimod Suppliers

Chembest Research Laboratories Limited
Tel
021-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6011
Advantage
61
ChemCell Biomedicine Co.,Ltd.
Tel
020-13556033878 2965585218 13556033878
Fax
0086-0757-85406358
Email
chemcell@hotmail.com
Country
China
ProdList
369
Advantage
52
Beijing Yisiyan Technology Research Center
Tel
010-56645598 13366904824
Fax
01062230033
Email
bjkaida@163.com
Country
China
ProdList
1664
Advantage
59
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66099280 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19918
Advantage
55
ShangHai Caerulum Pharma Discovery Co., Ltd.
Tel
18149758185
Email
sales-cpd@caerulumpharma.com
Country
China
ProdList
3421
Advantage
58
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Shanghai Macklin Biochemical Co.,Ltd.
Tel
15221275939 15221275939
Fax
021-50706099
Email
shenlinxing@macklin.cn
Country
China
ProdList
15878
Advantage
55
Hangzhou J&H Chemical Co., Ltd.
Tel
+86-571-87396432
Fax
0571-87396431
Email
sales@jhechem.com
Country
China
ProdList
10015
Advantage
53
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4121
Advantage
55
Shanghai Synchem Pharma Co., ltd
Tel
021-61984905-1 18016477331
Email
synchempharma@aliyun.com
Country
China
ProdList
6454
Advantage
55

248282-01-1, PaquinimodRelated Search:


  • ABR?215757
  • N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
  • ABR 25757
  • ABR 25757;ABR-25757;ABR25757;PAQUINIMOD;248282-01-1
  • ABR25757
  • ABR-25757
  • ABR?215757; ABR 215757; ABR215757; PAQUINIMOD.
  • Paquinimod
  • N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide
  • 3-Quinolinecarboxamide, N,5-diethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-
  • ABR-25757,Inhibitor,ABR25757,inhibit,Paquinimod
  • 248282-01-1