Paquinimod

Product Name: Paquinimod
CAS No.: 248282-01-1
Chemical Name: Paquinimod
Synonyms: ABR25757;ABR 25757;ABR-25757;ABR?215757;Paquinimod;ABR?215757; ABR 215757; ABR215757; PAQUINIMOD.;ABR-25757,Inhibitor,ABR25757,inhibit,Paquinimod;ABR 25757;ABR-25757;ABR25757;PAQUINIMOD;248282-01-1;N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide;N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide
CBNumber: CB92498835
Molecular Formula: C21H22N2O3
Formula Weight: 350.41
MOL File: 248282-01-1.mol

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Paquinimod Property

Boiling point:: 487.3±45.0 °C(Predicted)
Density: 1.267±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:15.0(Max Conc. mg/mL);42.8(Max Conc. mM)
form: A solid
pka: 4.50±1.00(Predicted)
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28443
Product name: Paquinimod
Packaging: 1mg
Price: $55
Updated: 2024/03/01

Cayman Chemical

Product number: 28443
Product name: Paquinimod
Packaging: 25mg
Price: $914
Updated: 2024/03/01

Cayman Chemical

Product number: 28443
Product name: Paquinimod
Packaging: 5mg
Price: $224
Updated: 2024/03/01

Cayman Chemical

Product number: 28443
Product name: Paquinimod
Packaging: 10mg
Price: $420
Updated: 2024/03/01

AK Scientific

Product number: 1997DM
Product name: Paquinimod
Packaging: 5mg
Price: $146
Updated: 2021/12/16

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Paquinimod Chemical Properties,Usage,Production

Uses

Paquinimod is a S100A9 inhibitor preventing S100A9 binding to TLR-4. Paquinimod reduces pathology in experimental collagenase-induced osteoarthritis. Paquinimod treatment of collagenase-induced OA (CIOA) resulted in significantly reduced synovial thickening (57%), osteophyte size at the medial femur (66%) and cruciate ligaments (67%) and cartilage damage at the medial tibia (47%) and femur (75%; n=7, untreated n=6). Paquinimod reduces leukocyte recruitment during sterile inflammation. Paquinimod also reduced priming of proinflammatory effector CD4(+) T cells.

Paquinimod Preparation Products And Raw materials

Raw materials

Preparation Products

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Paquinimod Suppliers

China 60 India 1 United States 6 Global 67

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

ChemCell Biomedicine Co.,Ltd.

Tel: 020-13556033878 2965585218 13556033878
Fax: 0086-0757-85406358
Email: chemcell@hotmail.com
Country: China
ProdList: 369
Advantage: 52

Beijing Yisiyan Technology Research Center

Tel: 010-56645598 13366904824
Fax: 01062230033
Email: bjkaida@163.com
Country: China
ProdList: 1637
Advantage: 59

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66099280 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19915
Advantage: 55

ShangHai Caerulum Pharma Discovery Co., Ltd.

Tel: 18149758185 18149758185
Email: sales-cpd@caerulumpharma.com
Country: China
ProdList: 3466
Advantage: 58

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 41462
Advantage: 60

Shanghai Macklin Biochemical Co.,Ltd.

Tel: 15221275939 15221275939
Fax: 021-50706099
Email: shenlinxing@macklin.cn
Country: China
ProdList: 16166
Advantage: 55

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-+86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 11481
Advantage: 59

Shanghai Lollane Biological Technology Co.,Ltd.

Tel: 021-52996696，15000506266 15000506266
Fax: +86-21-52996696
Country: China
ProdList: 4512
Advantage: 55

Shanghai Synchem Pharma Co., ltd

Tel: 21-619849051-1 18521059765
Email: synchempharma@aliyun.com
Country: China
ProdList: 6463
Advantage: 55

248282-01-1, PaquinimodRelated Search:

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ABR?215757

N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenyl-1,2-dihydroquinoline-3-carboxamide

ABR 25757

ABR 25757;ABR-25757;ABR25757;PAQUINIMOD;248282-01-1

ABR25757

ABR-25757

ABR?215757; ABR 215757; ABR215757; PAQUINIMOD.

Paquinimod

N,5-diethyl-4-hydroxy-1-methyl-2-oxo-N-phenylquinoline-3-carboxamide

3-Quinolinecarboxamide, N,5-diethyl-1,2-dihydro-4-hydroxy-1-methyl-2-oxo-N-phenyl-

ABR-25757,Inhibitor,ABR25757,inhibit,Paquinimod

248282-01-1