Methyl 5-aminopentanoate hydrochloride
- Product Name
- Methyl 5-aminopentanoate hydrochloride
- CAS No.
- 29840-56-0
- Chemical Name
- Methyl 5-aminopentanoate hydrochloride
- Synonyms
- Methyl 5-amino-pentanoate HCl;Methyl 5-aminovalerate hydrochloride;Ethyl 5-aMinopentanoate hydrochloride;Methyl 5-aminopentanoate hydrochloride;5-Amino-pentanoic acid methyl ester HCl;methyl 5-aminopentanoate hydrochloride (1:1);5-Aminopentanoic acid methyl ester hydrochloride;delta-Aminovaleric acid methyl ester hydrochloride;5-amino-Pentanoic acid methyl ester hydrochloride (1:1);methyl ester- 5-amino- Pentanoic acid, hydrochloride (1:1)
- CBNumber
- CB92502507
- Molecular Formula
- C6H14ClNO2
- Formula Weight
- 167.63386
- MOL File
- 29840-56-0.mol
Methyl 5-aminopentanoate hydrochloride Property
- Melting point:
- 145.5-147℃
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
- form
- Solid
- color
- White to Off-White
- InChI
- InChI=1S/C6H13NO2.ClH/c1-9-6(8)4-2-3-5-7;/h2-5,7H2,1H3;1H
- InChIKey
- FAKIZCQRTPAOSH-UHFFFAOYSA-N
- SMILES
- C(OC)(=O)CCCCN.[H]Cl
Safety
- HS Code
- 2922498590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- M287050
- Product name
- Methyl5-AminopentanoateHydrochloride
- Packaging
- 1g
- Price
- $150
- Updated
- 2021/12/16
- Product number
- KMA0192
- Product name
- Methyl5-aminopentanoatehydrochloride
- Packaging
- 5g
- Price
- $350.9
- Updated
- 2021/12/16
- Product number
- CHM0122507
- Product name
- METHYL 5-AMINOPENTANOATE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $648.81
- Updated
- 2021/12/16
- Product number
- CHM0122507
- Product name
- METHYL 5-AMINOPENTANOATE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 2.5G
- Price
- $852.21
- Updated
- 2021/12/16
- Product number
- CHM0122507
- Product name
- METHYL 5-AMINOPENTANOATE HYDROCHLORIDE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $1005.43
- Updated
- 2021/12/16
Methyl 5-aminopentanoate hydrochloride Chemical Properties,Usage,Production
Uses
Methyl 5-Aminopentanoate Hydrochloride is used as a reactant to synthesize several compounds with therapeutic potential.
Synthesis
67-56-1
660-88-8
29840-56-0
5-Aminopentanoic acid (22.45 mmol, 1.0 equiv) was dissolved in 20-30 mL of anhydrous methanol in a two-necked flask equipped with a reflux condenser. Thionyl chloride (31.43 mmol, 1.4 equiv) was slowly added dropwise over 5-10 min. After the dropwise addition, the reaction mixture was heated and refluxed for 3 hours. Subsequently, the mixture was stirred at room temperature overnight. After completion of the reaction, the solvent was removed by rotary evaporator (RVE). The white or light yellow solid obtained was washed with hexane (3 x 50 mL) and evaporated with another portion of hexane. The product was dried under low pressure to give methyl 5-aminopentanoate hydrochloride (2a) as a translucent solid in a yield of 3.46 g (92% yield). Melting point: 141-143 °C (literature value 146.3 °C [42]); 1H NMR (300 MHz, D2O): δ = 3.57 (s, 3H, COOCH3), 2.88 (t, 2H, J = 7.0 Hz, C5-H2), 2.30-2.35 (m, 2H, C2-H2), 1.53-1.59 (m, 4H, C3-H2), 1.53-1.59 (m, 4H, C3-H2, C4-H2). C3-H2 and C4-H2) ppm; 13C NMR (75 MHz, D2O): δ = 179.2 (C1), 54.7 (COOCH3), 41.6 (C5), 35.5 (C2), 28.6 (C4), 23.6 (C3) ppm; IR (solid): ν = 3021(s), 2945(s), 1735(s) ), 1596 (m), 1576 (m), 1519 (s), 1474 (w), 1444 (w), 1414 (w), 1346 (w), 1271 (m), 1187 (s), 1152 (m), 1068 (w), 1055 (m), 984 (w), 952 (m), 899 (w), 882 (w), 865 (w ), 748(s), 651(w) cm-1.
References
[1] Journal of Medicinal Chemistry, 2006, vol. 49, # 20, p. 6094 - 6103
[2] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 10, p. 2730 - 2742
[3] Angewandte Chemie - International Edition, 2013, vol. 52, # 28, p. 7228 - 7232
[4] Angew. Chem., 2013, vol. 125, # 28, p. 7369 - 7373,5
[5] Organic and Biomolecular Chemistry, 2016, vol. 14, # 25, p. 6010 - 6023
Methyl 5-aminopentanoate hydrochloride Preparation Products And Raw materials
Raw materials
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View Lastest Price from Methyl 5-aminopentanoate hydrochloride manufacturers
- Product
- Methyl 5-aminopentanoate hydrochloride 29840-56-0
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-09-26
- Product
- methyl 5-aminopentanoate,hydrochloride 29840-56-0
- Price
- US $0.01/KG
- Min. Order
- 1KG
- Purity
- 98%; 99%
- Supply Ability
- 500g;1kg； 25kg
- Release date
- 2020-01-09