3-CHLORO-4-IODOPYRIDINE

Product Name: 3-CHLORO-4-IODOPYRIDINE
CAS No.: 77332-79-7
Chemical Name: 3-CHLORO-4-IODOPYRIDINE
Synonyms: oro-4-iodopyridine;3-CHLORO-4-IODOPYRIDINE;Pyridine, 3-chloro-4-iodo-;3-chloro -4-pyridine iodide;3-Chloro-4-iodopyridine 97%;3-CHLORO-4-IODOPYRIDINE ISO 9001：2015 REACH
CBNumber: CB9251371
Molecular Formula: C5H3ClIN
Formula Weight: 239.44
MOL File: 77332-79-7.mol

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3-CHLORO-4-IODOPYRIDINE Property

Melting point:: 104-108 °C
Boiling point:: 245℃
Density: 2.052
Flash point:: 102℃
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 1.57±0.18(Predicted)
form: Solid
color: White to Light yellow to Light orange
λmax: 272nm(MeOH)(lit.)
Sensitive: Light Sensitive

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Safety

Hazard Codes: T,Xn
Risk Statements: 22-37/38-41
Safety Statements: 26-36/37/39
WGK Germany: nwg
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C2971
Product name: 3-Chloro-4-iodopyridine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $110
Updated: 2025/07/31

TRC

Product number: C367290
Product name: 3-Chloro-4-iodopyridine
Packaging: 5g
Price: $205
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-M-X6
Product name: 3-Chloro-4-iodopyridine
Packaging: 100mg
Price: $20
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC142381
Product name: 3-Chloro-4-iodopyridine
Packaging: 1g
Price: $52
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC142381
Product name: 3-Chloro-4-iodopyridine
Packaging: 2g
Price: $80
Updated: 2021/12/16

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3-CHLORO-4-IODOPYRIDINE Chemical Properties,Usage,Production

Uses

3-Chloro-4-iodopyridine, can be used for the preparation of difluoromethylated pyridines. It is also an intermediate for the synthesis of 5-Chloro-4-(trifluoromethyl)-2-pyridinecarboxylic Acid (C421715).

Synthesis

626-60-8

77332-79-7

General procedure for the synthesis of 3-chloro-4-iodopyridine using 3-chloropyridine as starting material: lithium diisopropylammonium (LDA, 5.9 mL, 8.88 mmol) was slowly added to a cooled tetrahydrofuran (THF, 30.0 mL) solution of 3-chloropyridine (1.0 g, 8.88 mmol) at -75 °C. The reaction mixture was stirred continuously at -75 °C for 4 hours. Subsequently, iodine (2.2 g, 8.88 mmol) was added and stirring was continued at the same temperature for 1 hour. Upon completion of the reaction, the mixture was quenched with ice water at -70 °C, the organic layer was extracted with ethyl acetate, the organic phases were combined and concentrated to give 0.500 g of the target product 3-chloro-4-iodopyridine. The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 8.01 (d, J = 5.1 Hz, 1H), 8.14 (d, J = 4.8 Hz, 1H), 8.63 (s, 1H).

References

[1] Angewandte Chemie - International Edition, 2008, vol. 47, # 5, p. 888 - 890
[2] Tetrahedron Letters, 2004, vol. 45, # 42, p. 7873 - 7877
[3] Tetrahedron, 1993, vol. 49, # 1, p. 49 - 64
[4] Patent: US6169086, 2001, A
[5] Patent: WO2008/57209, 2008, A1. Location in patent: Page/Page column 54-55

3-CHLORO-4-IODOPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-CHLORO-4-IODOPYRIDINE Suppliers

Americas 1 China 132 Czech Republic 1 Europe 1 Germany 2 India 7 Japan 1 Jordan 1 Switzerland 1 United Kingdom 4 United States 18 Global 169

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Pure Chemistry Scientific Inc.

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Tetranov Biopharm

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View Lastest Price from 3-CHLORO-4-IODOPYRIDINE manufacturers

Dideu Industries Group Limited

Product: 3-CHLORO-4-IODOPYRIDINE 77332-79-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-01

Career Henan Chemical Co

Product: 3-CHLORO-4-IODOPYRIDINE 77332-79-7
Price: US $3.00/KG
Min. Order: 1KG
Purity: 99%min
Supply Ability: 300kg
Release date: 2020-03-06

Career Henan Chemical Co

Product: 3-CHLORO-4-IODOPYRIDINE 77332-79-7
Price: US $5.50/KG
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1kg-100kg
Release date: 2020-01-10

77332-79-7, 3-CHLORO-4-IODOPYRIDINERelated Search:

Pyridine, 2,4-dichloro-5-iodo- 6-CHLORO-2-IODO-3-HYDROXYPYRIDINE 3-CHLORO-6-FLUORO-4-IODO-2-PICOLINE 3-CHLORO-4-IODOPYRIDINE 2,6-Dichloro-3-iodopyridine 4-CHLORO-3-IODOPYRIDINE 2-Chloro-3-iodopyridine, 98+%,2-CHLORO-3-IODOPYRIDINE 2 6-DICHLORO-4-IODOPYRIDINE 97 5-CHLORO-2-IODOPYRIDINE 2-Chloro-3-formyl-4-iodopyridine, 2-Chloro-4-iodopyridine-3-carboxaldehyde,2-CHLORO-4-IODOPYRIDINE-3-CARBOXALDEHYDE 2,5-Dichloro-4-iodopyridine 2-CHLORO-4-IODOPYRIDINE,2-CHLORO-4-IODOPYRIDINE,99% 2-CHLORO-5-IODOPYRIDINE,2-Chloro-5-iodopyridine,98%,2-chloro-5-iodopyridine 98% 2g 2-Chloro-6-iodopyridine 2,5-DICHLORO-3-IODOPYRIDINE 2-CHLORO-4-IODOPYRIDINE-3-METHANOL 4-Bromo-2-chloro-3-iodopyridine 98% 5-CHLORO-4-IODO-1H-PYRROLO[2,3-B]PYRIDINE

3-Chloro-4-iodopyridine 97%

3-chloro -4-pyridine iodide

Pyridine, 3-chloro-4-iodo-

3-CHLORO-4-IODOPYRIDINE

oro-4-iodopyridine

3-CHLORO-4-IODOPYRIDINE ISO 9001：2015 REACH

77332-79-7

77332-79-2

C5H3NClI

compounds of pyridine

Heterocycle-Pyridine series

pharmacetical

Halides

Pyridines