4-CHLORO-3-IODOPYRIDINE

Product Name: 4-CHLORO-3-IODOPYRIDINE
CAS No.: 89167-34-0
Chemical Name: 4-CHLORO-3-IODOPYRIDINE
Synonyms: CHLORO-3-IODOPYRIDINE;4-CHLORO-3-IODOPYRIDINE;3-Iodo-4-chloropyridine;Pyridine,4-chloro-3-iodo-;3-Iodo-4-iodomethyl-pyridine;4-Chloro-3-iodo-pyridine 97%;4-CHLORO-3-IODOPYRIDINE ISO 9001：2015 REACH
CBNumber: CB2432896
Molecular Formula: C5H3ClIN
Formula Weight: 239.44
MOL File: 89167-34-0.mol

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4-CHLORO-3-IODOPYRIDINE Property

Melting point:: 69-70°C
Boiling point:: 248.6±20.0 °C(Predicted)
Density: 2.052±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: solid
pka: 1.89±0.10(Predicted)
Appearance: Off-white to light yellow Solid
InChI: InChI=1S/C5H3ClIN/c6-4-1-2-8-3-5(4)7/h1-3H
InChIKey: GPFGRYFMMHDHGA-UHFFFAOYSA-N
SMILES: C1=NC=CC(Cl)=C1I

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Safety

Hazard Codes: Xi,N,Xn
Risk Statements: 22-38-41-50
Safety Statements: 26-39-61
RIDADR: 3077
WGK Germany: 3
HazardClass: IRRITANT
PackingGroup: Ⅲ
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H318Causes serious eye damage

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 775576
Product name: 4-Chloro-3-iodo-pyridine
Purity: 97%
Packaging: 1g
Price: $163
Updated: 2023/06/20

TRC

Product number: C367628
Product name: 4-Chloro-3-iodopyridine
Packaging: 50mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: J94917
Product name: 4-Chloro-3-iodopyridine
Packaging: 1g
Price: $48
Updated: 2021/12/16

Matrix Scientific

Product number: 018308
Product name: 4-Chloro-3-iodopyridine
Purity: 97%
Packaging: 1g
Price: $64
Updated: 2021/12/16

AK Scientific

Product number: J94917
Product name: 4-Chloro-3-iodopyridine
Packaging: 5g
Price: $125
Updated: 2021/12/16

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4-CHLORO-3-IODOPYRIDINE Chemical Properties,Usage,Production

Synthesis

626-61-9

89167-34-0

The general procedure for the synthesis of 4-chloro-3-iodopyridine from 4-chloropyridine was as follows: suspension of 4-chloropyridine (10 g, 0.067 mol) in dry THF (150 mL) and slow dropwise addition of LDA (134 mL, 1 M hexane solution) at a temperature below -70 °C. The reaction mixture was stirred at -78 °C for 30 min before adding an anhydrous THF solution of I2 (17 g, 0.067 mol), keeping the internal temperature below -65 °C for 10 min. Subsequently, the reaction mixture was slowly warmed up to room temperature over a period of 2 hours and stirring was continued at room temperature for 30 minutes. Upon completion of the reaction, the mixture was poured into 20% aqueous Na2SO3 solution (100 mL) and extracted with EtOAc (100 mL, three times). The organic layer was washed sequentially with aqueous NaHCO3 (50 mL) and saturated aqueous NaCl (50 mL), dried and the solvent was evaporated. The product was purified by washing with petroleum ether (20 mL) to give 4-chloro-3-iodopyridine (6.2 g, 38% yield).'' HNMR (400 MHz, MeOD) δ 8.92 (s, 1H), 8.43-8.41 (d, 1H, J = 8Hz), 7.62-7.60 (d, 1H, J = 8Hz).

References

[1] Tetrahedron Letters, 2004, vol. 45, # 42, p. 7873 - 7877
[2] Journal of the American Chemical Society, 2002, vol. 124, # 4, p. 576 - 582
[3] Patent: WO2013/78254, 2013, A1. Location in patent: Paragraph 00359
[4] Heterocycles, 1996, vol. 43, # 8, p. 1641 - 1652

4-CHLORO-3-IODOPYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-3-IODOPYRIDINE Suppliers

China 90 Germany 1 India 6 United Kingdom 2 United States 11 Global 110

Shanghai Amico Chemicals Co. LTD

Tel: 微信 17321281695 18019252918
Fax: qq:1454668768
Email: 1454668768@qq.com
Country: China
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Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
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Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
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Accela ChemBio Co.,Ltd.

Tel: 021-50795510 4000665055
Fax: 021-50795055
Email: sales@accelachem.com
Country: China
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Nanjing Chemlin Chemical Co., Ltd

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Fax: +86-25-83453306
Email: info@chemlin.com.cn
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Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
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SuZhou ShiYa Biopharmaceuticals, Inc.

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Country: China
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Shanghai Witofly Chemical Co.,Ltd

Tel
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Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
Country: China
ProdList: 7865
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View Lastest Price from 4-CHLORO-3-IODOPYRIDINE manufacturers

Dideu Industries Group Limited

Product: 4-CHLORO-3-IODOPYRIDINE 89167-34-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons min
Release date: 2021-09-01

Career Henan Chemical Co

Product: 4-CHLORO-3-IODOPYRIDINE 89167-34-0
Price: US $6.68/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-08

89167-34-0, 4-CHLORO-3-IODOPYRIDINERelated Search:

4-CHLORO-3-IODOPYRIDINE 2,5-DICHLORO-3-IODOPYRIDINE 2,5-Dichloro-4-iodopyridine 2-Chloro-6-iodopyridine 2-CHLORO-4-IODOPYRIDINE,99%,2-CHLORO-4-IODOPYRIDINE 2-chloro-5-iodopyridine 98% 2g,2-Chloro-5-iodopyridine,98%,2-CHLORO-5-IODOPYRIDINE 3-Chloro-2-iodopyridine 4-Bromo-2-chloro-3-iodopyridine 98% 2-CHLORO-4-IODOPYRIDINE-3-METHANOL Pyridine, 2-fluloro-4-chloro-5-iodo- 2-AMINO-5-CHLORO-4-IODOPYRIDINE,2-AMINO-5-CHLORO-3-IODOPYRIDINE 3-BROMO-2-CHLORO-4-IODOPYRIDINE 5-CHLORO-2-IODOPYRIDINE 2-Chloro-3-formyl-4-iodopyridine, 2-Chloro-4-iodopyridine-3-carboxaldehyde,2-CHLORO-4-IODOPYRIDINE-3-CARBOXALDEHYDE 6-CHLORO-2-IODO-3-HYDROXYPYRIDINE 3-CHLORO-4-IODOPYRIDINE Pyridine, 2,4-dichloro-5-iodo- 4-CHLORO-3-IODOQUINOLINE

4-CHLORO-3-IODOPYRIDINE

CHLORO-3-IODOPYRIDINE

Pyridine,4-chloro-3-iodo-

3-Iodo-4-iodomethyl-pyridine

3-Iodo-4-chloropyridine

4-Chloro-3-iodo-pyridine 97%

4-CHLORO-3-IODOPYRIDINE ISO 9001：2015 REACH

89167-34-0

Pyridine

Pyridines

Heterocycle-Pyridine series

alkyl chloride|alkyl Iodine