Tubulysin A,TubA
- Product Name
- Tubulysin A,TubA
- CAS No.
- 205304-86-5
- Chemical Name
- Tubulysin A,TubA
- Synonyms
- TubA;CS-1324;Tubulysin A;Tubulysins A;Tubulysin A,TubA;(2S,4R)-4-[[2-[(1R,3R)-1-acetyloxy-4-methyl-3-[3-methylbutanoyloxymethyl-[(2S,3S)-3-methyl-2-[[(2R)-1-methylpiperidine-2-carbonyl]amino]pentanoyl]amino]pentyl]-1,3-thiazole-4-carbonyl]amino]-5-(4-hydroxyphenyl)-2-methylpentanoicaci;Benzenepentanoic acid, γ-[[[2-[(1R,3R)-1-(acetyloxy)-4-methyl-3-[[(2S,3S)-3-methyl-2-[[[(2R)-1-methyl-2-piperidinyl]carbonyl]amino]-1-oxopentyl][(3-methyl-1-oxobutoxy)methyl]amino]pentyl]-4-thiazolyl]carbonyl]amino]-4-hydroxy-α-methyl-, (αS,γR)-
- CBNumber
- CB92518395
- Molecular Formula
- C43H65N5O10S
- Formula Weight
- 844.07
- MOL File
- 205304-86-5.mol
Tubulysin A,TubA Property
- Melting point:
- 106-108 °C(Solv: methanol (67-56-1); water (7732-18-5))
- Boiling point:
- 979.9±65.0 °C(Predicted)
- Density
- 1.195±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- organic solvents: soluble
- form
- film
- pka
- 4.52±0.23(Predicted)
- color
- colorless or white
Safety
- Hazard Codes
- T
- Risk Statements
- 23/24/25-36/37/38
- Safety Statements
- 36/37-45
- RIDADR
- UN 2811 6.1 / PGIII
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
H311Toxic in contact with skin
H315Causes skin irritation
H319Causes serious eye irritation
H331Toxic if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P311Call a POISON CENTER or doctor/physician.
N-Bromosuccinimide Price
- Product number
- T897135
- Product name
- TubulysinA
- Packaging
- 0.25mg
- Price
- $385
- Updated
- 2021/12/16
- Product number
- T897135
- Product name
- TubulysinA
- Packaging
- 1mg
- Price
- $1405
- Updated
- 2021/12/16
- Product number
- T897135
- Product name
- TubulysinA
- Packaging
- 2.5mg
- Price
- $2805
- Updated
- 2021/12/16
- Product number
- T897135
- Product name
- TubulysinA
- Packaging
- 5mg
- Price
- $4235
- Updated
- 2021/12/16
- Product number
- PEP0004574
- Product name
- TUBULYSIN A
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $2684.85
- Updated
- 2021/12/16
Tubulysin A,TubA Chemical Properties,Usage,Production
Uses
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, an apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative.
Definition
ChEBI: Tubulysin A is a diester and a carboxylic acid.
Biochem/physiol Actions
Tubulysin A is a novel antibiotic, which is anti-microtubule, anti-mitotic, apoptosis inducer, anticancer, anti-angiogenic, and antiproliferative. Tubulysins are cytotoxic peptides, which include 9 members (A-I). Tubulysin A has potential application as an anticancer agent. It arrests cells in the G2/M phase. Tubulysin A inhibits polymerization more efficiently than vinblastine and induces depolymerization of isolated microtubules. Tubulysin A has potent cytostatic effects on various tumor cell lines with IC50 in the picomolar range.
Tubulysin A,TubA Preparation Products And Raw materials
Raw materials
Preparation Products
Tubulysin A,TubA Suppliers
View Lastest Price from Tubulysin A,TubA manufacturers
- Product
- Tubulysin A,TubA 205304-86-5
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- ≥98%
- Supply Ability
- g/kg/Ton
- Release date
- 2019-12-25