Brevilin A

Product Name: Brevilin A
CAS No.: 16503-32-5
Chemical Name: Brevilin A
Synonyms: 6-OAP;Brevilin A;Brevelin A;brevillin A;6-O-Angeloylplenolin;(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (Z)-2-methylbut-2-enoate;(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a ,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (2Z)-2-methyl-2-bu tenoate;2-Butenoic acid,2-methyl-,(3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-ylester, (2Z)-
CBNumber: CB92519594
Molecular Formula: C20H26O5
Formula Weight: 346.42
MOL File: 16503-32-5.mol

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Brevilin A Property

Boiling point:: 494.0±45.0 °C(Predicted)
Density: 1.17±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO:100.0(Max Conc. mg/mL);288.67(Max Conc. mM)
form: A solid
color: White to off-white
InChIKey: KUPPZVXLWANEJJ-UXPPPGSFSA-N
SMILES: C(O[C@H]1[C@]2([H])[C@H](C)C(=O)O[C@]2([H])C[C@@H](C)[C@@]2([H])[C@@]1(C)C(=O)C=C2)(=O)/C(/C)=C\C

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: PHL84204
Product name: Brevilin A
Purity: phyproof? Reference Substance
Packaging: 10MG
Price: $629
Updated: 2024/03/01

ChemScene

Product number: CS-0023593
Product name: Brevilin A
Purity: 99.77%
Packaging: 5mg
Price: $250
Updated: 2021/12/16

ChemScene

Product number: CS-0023593
Product name: Brevilin A
Purity: 99.77%
Packaging: 10mg
Price: $430
Updated: 2021/12/16

Crysdot

Product number: CD32002260
Product name: Brevilin A
Purity: 95+%
Packaging: 5mg
Price: $450
Updated: 2021/12/16

AvaChem

Product number: 4099
Product name: Brevilin A
Packaging: 10mg
Price: $490
Updated: 2021/12/16

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Brevilin A Chemical Properties,Usage,Production

Uses

Brevilin A can be used using a selective extraction method to obtain natural substances, and can also be applied to prepare derivatives to use for anti-cancer activity.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Enzyme inhibitor

This naturally occurring sesquiterpenoid (FW = 346.40 g/mol; CAS 16503- 32-5) from the volatile oils of the plant Centipeda minima inhibits (IC50 = 10 μg/mL) STAT3 phosphorylation in the Jak/STAT signal transduction pathway of A549R cells. Brevilin A showed high specificity on Janus Kinase activity and following STAT3 signaling without directly affecting some other signals, including p65, AKT and GSK-3β phosphorylation, as well as Src kinase activity. Brevilin A is also an antibiotic with activity against Giardia (IC50 = 16 μM) and Entamoeba histolitica (IC50 = 4–9 μM).

Brevilin A Preparation Products And Raw materials

Raw materials

Preparation Products

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Brevilin A Suppliers

China 117 United States 7 Global 124

Chengdu PFID reference Technology Co., Ltd

Tel: 028-82610909 15882229804
Email: pufeide@foxmail.com
Country: China
ProdList: 2335
Advantage: 58

Hubei Danding Pharmaceutical Technology Co., Ltd

Tel: 18917019315 18917019315
Email: 18917019315@163.cn
Country: China
ProdList: 9161
Advantage: 58

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6005
Advantage: 61

BioBioPha Co., Ltd.

Tel: 0871-65217109 13211707573;
Fax: 0871-65215563
Email: y.liu@mail.biobiopha.com
Country: China
ProdList: 5653
Advantage: 65

Chengdu Biopurify Phytochemicals Ltd.

Tel: +86-028-82633397 18982077548
Fax: +86-28-82633165
Email: cwb1@biopurify.cn
Country: China
ProdList: 2376
Advantage: 60

Shanghai Tauto Biotech Co., Ltd.

Tel: 021-51320588
Fax: 0086-21-51320502
Email: tauto@tautobiotech.com
Country: China
ProdList: 3989
Advantage: 66

TargetMol Chemicals Inc.

Tel: 021-021-33632979 15002134094
Fax: 021-33632979
Email: marketing@targetmol.com
Country: China
ProdList: 7783
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Hangzhou J&H Chemical Co., Ltd.

Tel: 0571-+86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 11578
Advantage: 59

Shanghai Yongye Biotechnology Co., Ltd.

Tel: 86-021-61559134 15921386130
Fax: 021-55068248
Email: 3423497944@qq.com
Country: China
ProdList: 8144
Advantage: 55

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View Lastest Price from Brevilin A manufacturers

Shaanxi Haibo Biotechnology Co., Ltd

Product: Brevilin A 16503-32-5
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 2000ton
Release date: 2023-08-21

Career Henan Chemical Co

Product: Brevilin A 16503-32-5
Price: US $9.80/KG
Min. Order: 1g
Purity: ＞98%
Supply Ability: 20 tons
Release date: 2020-02-10

16503-32-5, Brevilin ARelated Search:

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Brevilin A

6-O-Angeloylplenolin

2-Butenoic acid,2-methyl-,(3S,3aR,4S,4aR,7aR,8R,9aR)-2,3,3a,4,4a,5,7a,8,9,9a-decahydro-3,4a,8-trimethyl-2,5-dioxoazuleno[6,5-b]furan-4-ylester, (2Z)-

(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a ,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (2Z)-2-methyl-2-bu tenoate

brevillin A

Brevelin A

6-OAP

(3S,3aR,4S,4aR,7aR,8R,9aR)-3,4a,8-Trimethyl-2,5-dioxo-2,3,3a,4,4a,5,7a,8,9,9a-decahydroazuleno[6,5-b]furan-4-yl (Z)-2-methylbut-2-enoate

16503-32-5