4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde

Product Name: 4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde
CAS No.: 148256-82-0
Chemical Name: 4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde
Synonyms: 4-chloro-2-(Methylthio)pyriMidine-5-carbaldehyde;4-Chloro-2-(methylthio)-5-pyrimidinecarbaldehyde;4-Chloro-2-(methylthio)-5-pyrimidinecarboxaldehyde;4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde;5-PyriMidinecarboxaldehyde, 4-chloro-2-(Methylthio)-;4-chloro-2-(Methylsulfanyl)pyriMidine-5- carbaldehyde;4-chloro-2-(methylsulfanyl)pyrimidine-5-carboxaldehyde;4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde ISO 9001：2015 REACH
CBNumber: CB92522598
Molecular Formula: C6H5ClN2OS
Formula Weight: 188.63
MOL File: 148256-82-0.mol

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4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde Property

Boiling point:: 315℃
Density: 1.44
Flash point:: 144℃
storage temp.: Inert atmosphere,Store in freezer, under -20°C
pka: -2.16±0.29(Predicted)
Appearance: Off-white to yellow Solid
InChI: InChI=1S/C6H5ClN2OS/c1-11-6-8-2-4(3-10)5(7)9-6/h2-3H,1H3
InChIKey: VMNYMIKGYQYJHK-UHFFFAOYSA-N
SMILES: C1(SC)=NC=C(C=O)C(Cl)=N1

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Safety

HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: C383688
Product name: 4-Chloro-2-(Methylthio)Pyrimidine-5-Carbaldehyde
Packaging: 100mg
Price: $90
Updated: 2021/12/16

TRC

Product number: C383688
Product name: 4-Chloro-2-(Methylthio)Pyrimidine-5-Carbaldehyde
Packaging: 500mg
Price: $310
Updated: 2021/12/16

Apolloscientific

Product number: OR919181
Product name: 4-Chloro-2-(methylthio)pyrimidine-5-carbaldehyde
Purity: 95%
Packaging: 1g
Price: $335
Updated: 2021/12/16

Matrix Scientific

Product number: 112516
Product name: 4-Chloro-2-(methylthio)pyrimidine-5-carbaldehyde
Packaging: 1g
Price: $397
Updated: 2021/12/16

Medical Isotopes, Inc.

Product number: 35873
Product name: 4-Chloro-2-(methylthio)pyrimidine-5-carbaldehyde
Purity: 95+%
Packaging: 250mg
Price: $452
Updated: 2021/12/16

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4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde Chemical Properties,Usage,Production

Synthesis

1044145-59-6

148256-82-0

General procedure for the synthesis of 4-chloro-2-(methylthio)pyrimidine-5-carbaldehyde from (4-chloro-2-(methylthio)pyrimidin-5-yl)methanol: Activated manganese(IV) oxide (38.1 g, 439 mmol, 5 μm) was added to (4-chloro-2-(methylthio)pyrimidin-5-yl)methanol (16.73 g, 87.8 mmol) in a chloroform ( 800 mL) solution. The reaction mixture was stirred overnight at room temperature and after completion of the reaction, it was filtered through a pad of diatomaceous earth to remove solid impurities. The filtrate was concentrated under reduced pressure to afford 4-chloro-2-(methylthio)pyrimidine-5-carbaldehyde (13.7 g, 82.8% yield). The product was characterized by 1H NMR (500 MHz, CDCl3): δ 10.31 (s, 1H), 8.88 (s, 1H), 2.65 (s, 3H) ppm.

References

[1] Patent: WO2009/85185, 2009, A1. Location in patent: Page/Page column 129
[2] Patent: US2015/31674, 2015, A1. Location in patent: Paragraph 0317
[3] ACS Medicinal Chemistry Letters, 2015, vol. 6, # 12, p. 1241 - 1246
[4] Patent: EP2112150, 2009, A1. Location in patent: Page/Page column 26; 28
[5] Patent: US2011/257207, 2011, A1. Location in patent: Page/Page column 21

4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde Suppliers

China 103 India 2 United Kingdom 1 United States 6 Global 112

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View Lastest Price from 4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde manufacturers

Dideu Industries Group Limited

Product: 4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde 148256-82-0
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-12-15

Career Henan Chemical Co

Product: 4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde 148256-82-0
Price: US $6.68/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2020-01-10

148256-82-0, 4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehydeRelated Search:

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4-chloro-2-(Methylthio)pyriMidine-5-carbaldehyde

5-PyriMidinecarboxaldehyde, 4-chloro-2-(Methylthio)-

4-chloro-2-(Methylsulfanyl)pyriMidine-5- carbaldehyde

4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde

4-chloro-2-(methylsulfanyl)pyrimidine-5-carboxaldehyde

4-Chloro-2-(methylthio)-5-pyrimidinecarboxaldehyde

4-Chloro-2-(methylthio)pyrimidine-5-carboxaldehyde ISO 9001：2015 REACH

4-Chloro-2-(methylthio)-5-pyrimidinecarbaldehyde

148256-82-0