2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE
- Product Name
- 2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE
- CAS No.
- 73225-15-7
- Chemical Name
- 2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE
- Synonyms
- 1-(4-nitrophenyl)-2-Methylimidazole;2-methyl-1-(4-nitrophenyl)imidazole;2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE;1H-Imidazole, 2-methyl-1-(4-nitrophenyl)-;2-Methyl-1-(4-nitrophenyl)-1H-imidazole95%
- CBNumber
- CB9255182
- Molecular Formula
- C10H9N3O2
- Formula Weight
- 203.2
- MOL File
- 73225-15-7.mol
2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE Property
- Melting point:
- 138-139 °C
- Boiling point:
- 396.5±44.0 °C(Predicted)
- Density
- 1.29±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 6.17±0.10(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- W8149
- Product name
- 2-Methyl-1-(4-nitrophenyl)-1H-imidazole
- Packaging
- 1g
- Price
- $104
- Updated
- 2021/12/16
- Product number
- 071884
- Product name
- 2-Methyl-1-(4-nitrophenyl)-1H-imidazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $139
- Updated
- 2021/12/16
- Product number
- 071884
- Product name
- 2-Methyl-1-(4-nitrophenyl)-1H-imidazole
- Purity
- 95+%
- Packaging
- 5g
- Price
- $360
- Updated
- 2021/12/16
- Product number
- COR0001803
- Product name
- 2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE
- Purity
- 95.00%
- Packaging
- 1G
- Price
- $440
- Updated
- 2021/12/16
- Product number
- COR0001803
- Product name
- 2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE
- Purity
- 95.00%
- Packaging
- 5G
- Price
- $520
- Updated
- 2021/12/16
2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE Chemical Properties,Usage,Production
Synthesis
693-98-1
350-46-9
73225-15-7
General procedure: 1-fluoro-4-nitrobenzene (10 g, 70.9 mmol), 2-methyl-1H-imidazole (5.8 g, 70.9 mmol) and cesium carbonate (Cs2CO3, 34.7 g, 106.4 mmol) were placed in degassed N,N-dimethylformamide (DMF, 200 mL). The mixture was heated to 100 °C and stirred overnight under nitrogen protection. The progress of the reaction was monitored by thin layer chromatography (TLC) and after confirming the complete consumption of 1-fluoro-4-nitrobenzene, the reaction mixture was concentrated under reduced pressure. Water (300 mL) was added to the concentrated residue and a gray precipitate was precipitated, which was separated by filtration to afford the target compound 2-methyl-1-(4-nitrophenyl)-1H-imidazole (12.8 g, 89% yield).
References
[1] Advanced Synthesis and Catalysis, 2016, vol. 358, # 4, p. 597 - 609
[2] Patent: WO2011/75478, 2011, A1. Location in patent: Page/Page column 53
[3] Patent: WO2009/71888, 2009, A1. Location in patent: Page/Page column 83
[4] Patent: US5298520, 1994, A
[5] Journal of Medicinal Chemistry, 1995, vol. 38, # 10, p. 1799 - 1810
2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE Suppliers
- Tel
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- Country
- Germany
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View Lastest Price from 2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE manufacturers
- Product
- 2-METHYL-1-(4-NITROPHENYL)-1H-IMIDAZOLE 73225-15-7
- Price
- US $1.00/g
- Min. Order
- 1g
- Purity
- 85.0-99.8%
- Supply Ability
- 20tons
- Release date
- 2020-10-28