YS121
- Product Name
- YS121
- CAS No.
- 916482-17-2
- Chemical Name
- YS121
- Synonyms
- YS121;YS121 Exclusive;HVJBWTVMRIOTEL-UHFFFAOYSA-N;Octanoic acid, 2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]-
- CBNumber
- CB92592892
- Molecular Formula
- C20H26ClN3O2S
- Formula Weight
- 407.96
- MOL File
- 916482-17-2.mol
YS121 Property
- Boiling point:
- 557.4±50.0 °C(Predicted)
- Density
- 1.25±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≤30mg/ml in ethanol;30mg/ml in DMSO;30mg/ml in dimethyl formamide
- pka
- 3.04±0.21(Predicted)
- form
- solution in acetate.
N-Bromosuccinimide Price
- Product number
- 13665
- Product name
- YS-121
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $55
- Updated
- 2024/03/01
- Product number
- 13665
- Product name
- YS-121
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $236
- Updated
- 2024/03/01
- Product number
- 13665
- Product name
- YS-121
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $420
- Updated
- 2024/03/01
- Product number
- 13665
- Product name
- YS-121
- Purity
- ≥98%
- Packaging
- 25mg
- Price
- $914
- Updated
- 2024/03/01
- Product number
- 1614DC
- Product name
- 2-[4-Chloro-6-(2,3-dimethylanilino)pyrimidin-2-yl]sulfanyloctanoicacid
- Packaging
- 10mg
- Price
- $564
- Updated
- 2021/12/16
YS121 Chemical Properties,Usage,Production
Description
Microsomal prostaglandin E2 synthase-
Definition
ChEBI: Octanoic acid, 2-[[4-chloro-6-[(2,3-dimethylphenyl)amino]-2-pyrimidinyl]thio]- is a medium-chain fatty acid.
References
[1] koeberle a, zettl h, greiner c, et al. pirinixic acid derivatives as novel dual inhibitors of microsomal prostaglandin e2 synthase-1 and 5-lipoxygenase[j]. journal of medicinal chemistry, 2008, 51(24): 8068-8076.
[2] mehrotra s, morimiya a, agarwal b, et al. microsomal prostaglandin e2 synthase‐1 in breast cancer: a potential target for therapy[j]. the journal of pathology, 2006, 208(3): 356-363.werz o, greiner c, koeberle a, et al. novel and potent inhibitors of 5-lipoxygenase product synthesis based on the structure of pirinixic acid[j]. journal of medicinal chemistry, 2008, 51(17): 5449-5453.koeberle a, rossi a, zettl h, et al. the molecular pharmacology and in vivo activity of 2-(4-chloro-6-(2, 3-dimethylphenylamino) pyrimidin-2-ylthio) octanoic acid (ys121), a dual inhibitor of microsomal prostaglandin e2 synthase-1 and 5-lipoxygenase[j]. journal of pharmacology and experimental therapeutics, 2010, 332(3): 840-848.
YS121 Preparation Products And Raw materials
Raw materials
Preparation Products
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