3-CyclopropylMethoxy-4-Hydroxybenzaldehyde
- Product Name
- 3-CyclopropylMethoxy-4-Hydroxybenzaldehyde
- CAS No.
- 25934-52-5
- Chemical Name
- 3-CyclopropylMethoxy-4-Hydroxybenzaldehyde
- Synonyms
- alpha-Cyclopropylvanillin;Roflumilast intermediates-4;3-CyclopropylMethoxy-4-Hydroxybenzaldehyde;4-(cyclopropylmethoxy)-3-hydroxybenzaldehyde;Benzaldehyde, 3-(cyclopropylmethoxy)-4-hydroxy-
- CBNumber
- CB92653937
- Molecular Formula
- C11H12O3
- Formula Weight
- 192.21
- MOL File
- 25934-52-5.mol
3-CyclopropylMethoxy-4-Hydroxybenzaldehyde Property
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
Safety
- HS Code
- 2912490090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- OR940968
- Product name
- 3-(Cyclopropylmethoxy)-4-hydroxybenzaldehyde
- Purity
- 95%
- Packaging
- 250mg
- Price
- $182
- Updated
- 2021/12/16
- Product number
- OR940968
- Product name
- 3-(Cyclopropylmethoxy)-4-hydroxybenzaldehyde
- Purity
- 95%
- Packaging
- 1g
- Price
- $414
- Updated
- 2021/12/16
- Product number
- CHM0389090
- Product name
- 3-(CYCLOPROPYLMETHOXY)-4-HYDROXYBENZALDEHYDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $503.06
- Updated
- 2021/12/16
- Product number
- 2178AB
- Product name
- 3-(Cyclopropylmethoxy)-4-hydroxybenzaldehyde
- Packaging
- 5g
- Price
- $577
- Updated
- 2021/12/16
- Product number
- 2178AB
- Product name
- 3-(Cyclopropylmethoxy)-4-hydroxybenzaldehyde
- Packaging
- 10g
- Price
- $928
- Updated
- 2021/12/16
3-CyclopropylMethoxy-4-Hydroxybenzaldehyde Chemical Properties,Usage,Production
Uses
3-(cyclopropylmethoxy)-4-hydroxybenzaldehyde is used as a reactant in the preparation of ethyl (alkoxy)?(cyclopropylmethoxy)?-?4-?hydroxy-?3-?quinolinecarboxylates.
Synthesis
1381886-14-1
25934-52-5
General procedure for the synthesis of 3-cyclopropylmethoxy-4-hydroxybenzaldehyde from 3-cyclopropylmethoxy-4-phenylmethoxybenzaldehyde: Unpurified 3-cyclopropylmethoxy-4-phenylmethoxybenzaldehyde was added directly to a 100 mL three-neck flask. Subsequently, ethyl acetate (EtOAc, 20 mL) and 10% Pd/C catalyst (136 mg, 0.13 mmol) were added. Hydrogen was introduced at room temperature and the reaction mixture was stirred for 2 h. The progress of the reaction was monitored by thin layer chromatography (TLC). Upon completion of the reaction, the solvent in the filtrate was removed by distillation under reduced pressure to afford a light yellow oily liquid 3-cyclopropylmethoxy-4-hydroxybenzaldehyde (Z-5, 1.69 g, 92% yield).
References
[1] Patent: CN105523954, 2016, A. Location in patent: Paragraph 0025
3-CyclopropylMethoxy-4-Hydroxybenzaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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