Irinotecan Hydroxyl Acid

Product Name: Irinotecan Hydroxyl Acid
CAS No.: 142677-15-4
Chemical Name: Irinotecan Hydroxyl Acid
Synonyms: Irinotecan IMpurity;Irinotecan Impurity 28;Irinotecan Hydroxyl Acid;SN 38 acid/SN-38 Carboxylate Disodium Salt;Indolizino[1,2-b]quinoline-7-acetic acid, α,12-diethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-, (αS)-;(S)-2-(12-ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoic acid, sodium salt (1:2)
CBNumber: CB92665752
Molecular Formula: C22H22N2O6
Formula Weight: 410.43
MOL File: 142677-15-4.mol

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Irinotecan Hydroxyl Acid Property

Boiling point:: 829.8±65.0 °C(Predicted)
Density: 1.54±0.1 g/cm3(Predicted)
solubility: DMSO (Slightly, Heated), Methanol (Slightly, Sonicated), Water (Slightly)
form: Solid
pka: 2.88±0.10(Predicted)
color: Light Yellow to Dark Yellow
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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Irinotecan Hydroxyl Acid Chemical Properties,Usage,Production

Uses

The active metabolite of Irinotecan (carboxylate form). SN-38 lactone and carboxylate may be considered pharmacokinetically distinct agents.

Irinotecan Hydroxyl Acid Preparation Products And Raw materials

Raw materials

Preparation Products

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142677-15-4, Irinotecan Hydroxyl AcidRelated Search:

12-ethyl-8-methyl-9-oxo-7-propionyl-9,11-dihydroindolizino[1,2-b]quinolin-2-yl [1,4'-bipiperidine]-1'-carboxylate (+)-Camptothecin N-Benzyl-4-piperidone 1-CHLOROCARBONYL-4-PIPERIDINOPIPERIDINE 4-Piperidinone Irinotecan Impurity 18 10-Hydroxycamptothecin 1-benzyl-4-(piperidin-1-yl)-1,2,3,6-tetrahydropyridine [1,4'-Bipiperidine]-1'-carboxylic acid Irinotecan Lactone IMpurity sodium:(2S)-2-[12-ethyl-8-(hydroxymethyl)-9-oxo-2-(4-piperidin-1-ylpiperidine-1-carbonyl)oxy-11H-indolizino[1,2-b]quinolin-7-yl]-2-hydroxybutanoate Irinotecan Impurity 26 Irinotecan 7,11-Diethyl-10-hydroxycaMptothecin Irinotecan Impurity 6 Irinotecan EP Impurity H 12-Hydroxy Irinotecan SN-38 GLUCURONIDE

Irinotecan IMpurity

Irinotecan Impurity 28

Indolizino[1,2-b]quinoline-7-acetic acid, α,12-diethyl-9,11-dihydro-α,2-dihydroxy-8-(hydroxymethyl)-9-oxo-, (αS)-

(S)-2-(12-ethyl-2-hydroxy-8-(hydroxymethyl)-9-oxo-9,11-dihydroindolizino[1,2-b]quinolin-7-yl)-2-hydroxybutanoic acid, sodium salt (1:2)

Irinotecan Hydroxyl Acid

SN 38 acid/SN-38 Carboxylate Disodium Salt

142677-15-4

1426706-06-7