Auristatin F

ChemicalBook > CAS DataBase List > Auristatin F

Product Name: Auristatin F
CAS No.: 163768-50-1
Chemical Name: Auristatin F
Synonyms: CS-1370;Auristatin F;Auristantin F;Auristatin F （AF）;Auristatin F TFA Salt;Auristatin F, 10 mM in DMSO;microtubule,VDA,cytotoxin,ADC Payload,Conjugate,vascular,Auristatin F,damaging,ADC Cytotoxin,inhibit,Microtubule/Tubulin,inhibitor,agent;L-Phenylalanine, N,N-dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-;N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide;(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(Dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid
CBNumber: CB92667493
Molecular Formula: C40H67N5O8
Formula Weight: 746
MOL File: 163768-50-1.mol

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Auristatin F Property

Melting point:: >140°C (dec.)
Boiling point:: 894.4±65.0 °C(Predicted)
Density: 1.112±0.06 g/cm3(Predicted)
storage temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility: DMSO (Slightly), Methanol (Slightly, Heated)
form: Solid
pka: 3.56±0.10(Predicted)
color: White to Off-White
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: A794100
Product name: AuristatinFTFASalt
Packaging: 2.5mg
Price: $300
Updated: 2021/12/16

TRC

Product number: A794100
Product name: AuristatinFTFASalt
Packaging: 10mg
Price: $795
Updated: 2021/12/16

ChemScene

Product number: CS-3436
Product name: AuristatinF
Purity: 99.79%
Packaging: 5mg
Price: $480
Updated: 2021/12/16

ChemScene

Product number: CS-3436
Product name: AuristatinF
Purity: 99.79%
Packaging: 1mg
Price: $190
Updated: 2021/12/16

ChemScene

Product number: CS-3436
Product name: AuristatinF
Purity: 99.79%
Packaging: 10mg
Price: $780
Updated: 2021/12/16

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Auristatin F Chemical Properties,Usage,Production

Description

Auristatin F is a cytotoxin that works as a microtubule inhibitor and vascular damaging agent.

Uses

Auristatin F is an antimitotic auristatin derivative that has been shown as a potent antitumor agent.

Auristatin F Preparation Products And Raw materials

Raw materials

Preparation Products

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163768-50-1, Auristatin FRelated Search:

3-(2'-DEOXY-BETA-D-2-RIBOFURANOSYL)PYRIDO[2,3-D]PYRIMIDINE-2,7(8H)-DIONE SINEFUNGIN F4 Auristatin E

Auristatin F

N,N-Dimethyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S)-1-carboxy-2-phenylethyl]amino}-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl}-3-methoxy-5-methyl-1-oxo-4-heptanyl]-N-methyl-L-valinamide

Auristantin F

CS-1370

Auristatin F TFA Salt

L-Phenylalanine, N,N-dimethyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-

Auristatin F （AF）

(S)-2-((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-2-((S)-2-(Dimethylamino)-3-methylbutanamido)-N,3-dimethylbutanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanamido)-3-phenylpropanoic acid

microtubule,VDA,cytotoxin,ADC Payload,Conjugate,vascular,Auristatin F,damaging,ADC Cytotoxin,inhibit,Microtubule/Tubulin,inhibitor,agent

Auristatin F, 10 mM in DMSO

163768-50-1

C40H67N5O8