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1-Boc-3-(4-BroMo-1H-pyrazol-1-yl)azetidine

Product Name
1-Boc-3-(4-BroMo-1H-pyrazol-1-yl)azetidine
CAS No.
877399-34-3
Chemical Name
1-Boc-3-(4-BroMo-1H-pyrazol-1-yl)azetidine
Synonyms
1-Boc-3-(4-bromo-1-pyrazolyl)azetidine;1-Boc-3-(4-BroMo-1H-pyrazol-1-yl)azetidine;1-Boc-3-(4-Bromo-1H-pyrazol-1-yl)azetidine - [B10912];tert-Butyl 3-(4-bromopyrazol-1-yl)azetidine-1-carboxylate;tert-butyl 3-(4-bromo-1H-pyrazol-1-yl)azetidine-1-carboxylate;1-Azetidinecarboxylic acid, 3-(4-bromo-1H-pyrazol-1-yl)-, 1,1-dimethylethyl ester
CBNumber
CB92704039
Molecular Formula
C11H16BrN3O2
Formula Weight
302.17
MOL File
877399-34-3.mol
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1-Boc-3-(4-BroMo-1H-pyrazol-1-yl)azetidine Property

storage temp. 
2-8°C
form 
solid
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHB00155
Product name
1-Boc-3-(4-bromo-1H-pyrazol-1-yl)azetidine
Purity
AldrichCPR
Packaging
1 g
Price
$330
Updated
2025/07/31
American Custom Chemicals Corporation
Product number
HCH0419576
Product name
TERT-BUTYL-3-(4-BROMO-1H-PYRAZOL-1-YL)AZETIDINE-1-CARBOXYLATE
Purity
95.00%
Packaging
5MG
Price
$456.7
Updated
2021/12/16
Matrix Scientific
Product number
122195
Product name
1-Boc-3-(4-Bromo-1H-pyrazol-1-yl)azetidine
Purity
97.0%
Packaging
1g
Price
$660
Updated
2021/12/16
Synthonix
Product number
B10912
Product name
1-Boc-3-(4-Bromo-1H-pyrazol-1-yl)azetidine
Purity
97.0%
Packaging
5g
Price
$790
Updated
2021/12/16
SynQuest Laboratories
Product number
4H56-9-3G
Product name
tert-Butyl 3-(4-bromo-1H-pyrazol-1-yl)azetidine-1-carboxylate
Purity
97.0%
Packaging
1g
Price
$900
Updated
2021/12/16
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1-Boc-3-(4-BroMo-1H-pyrazol-1-yl)azetidine Chemical Properties,Usage,Production

Synthesis

2075-45-8

141699-58-3

877399-34-3

N-Boc-3-methylsulfonyloxyazetidine (304 mg, 1.21 mmol), 4-bromopyrazole (178 mg, 1.21 mmol), a mineral oil suspension of 60% NaH (73 mg, 1.82 mmol), and 2 mL of DMF were added to the microwave tube.The reaction mixture was microwaved at 110 °C for 30 min. Upon completion of the reaction, the mixture was partitioned between EtOAc (200 mL) and saturated NaHCO3 solution (2 × 50 mL) and washed with brine (50 mL). The organic layer was dried over anhydrous Na2SO4 and concentrated under reduced pressure to give 360 mg of the yellow oily product tert-butyl 3-(4-bromo-1H-pyrazol-1-yl)azetidine-1-carboxylate in 98% yield.1H NMR (400 MHz, DMSO-D6) δ ppm 1.36-1.43 (m, 9H), 4.08 (s, 2H), 4.18- 4.31 (m, 2H), 5.12-5.22 (m, 1H), 7.67 (s, 1H), 8.14 (s, 1H).

References

[1] Patent: US2006/46991, 2006, A1. Location in patent: Page/Page column 57-58
[2] Patent: WO2006/21881, 2006, A2. Location in patent: Page/Page column 62-63; 64
[3] Journal of Medicinal Chemistry, 2011, vol. 54, # 18, p. 6342 - 6363

1-Boc-3-(4-BroMo-1H-pyrazol-1-yl)azetidine Preparation Products And Raw materials

Raw materials

Preparation Products

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1-Boc-3-(4-BroMo-1H-pyrazol-1-yl)azetidine Suppliers

China 51 India 1 United States 5 Global 57
Shanghai Rong Lin Medical Technology Co., Ltd.
Tel
18602194589
Email
lincy-110@163.com
Country
China
ProdList
863
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58
Shanghai XR Chemical Technology Co., Ltd.
Tel
021-31007982 18019432809
Fax
021-31007982
Email
info@xrpharma.com
Country
China
ProdList
676
Advantage
55
SPIRO PHARMA
Tel
Fax
-
Email
eric_feng1954@126.com
Country
China
ProdList
9248
Advantage
55
Chengdu J&B Technology Co., Ltd.
Tel
028-61186694 15608078506
Fax
028-61186694
Email
609128801@qq.com
Country
China
ProdList
837
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55
Tianjin Being Technology Co., Ltd.
Tel
18622939839
Fax
QQ:343281693
Email
tjby921@163.com
Country
China
ProdList
884
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55
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58
Aikon International Limited
Tel
025-58859352 18068836627
Fax
(5)02557626880
Email
dt3@aikonchem.com
Country
China
ProdList
15493
Advantage
58
Jiangsu yize medical technology co. LTD
Tel
18962082606
Fax
QQ: 3394205705
Email
3394205705@qq.com
Country
China
ProdList
1751
Advantage
58
Yujinpharma(Tianjin) Technology Co.,Ltd.
Tel
13370351217 kungfu1217@1
Fax
QQ1400885609
Email
kungfu1217@163.com
Country
China
ProdList
2720
Advantage
58
Shanghai SPAR pharmaceutical technology co., LTD
Tel
021-000000 13917643586;
Email
admin@jingshipharmatech.com
Country
China
ProdList
9859
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58

877399-34-3, 1-Boc-3-(4-BroMo-1H-pyrazol-1-yl)azetidineRelated Search:

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  • 877399-34-3