ChemicalBook > CAS DataBase List > N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine

Product Name
N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine
CAS No.
1421372-94-2
Chemical Name
N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine
Synonyms
N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine;N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine;EOS-61221;AZD9291 1;AZD9291 N-3;Osimertinib N-3;AZD9291 Intermediate 2;OSIMERTINIB INTERMEDIATE 1;Osimertinib mesylate intermediate 1;N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)p...
CBNumber
CB92710519
Molecular Formula
C20H16FN5O3
Formula Weight
393.37
MOL File
1421372-94-2.mol
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N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Property

Melting point:
>250°C (dec.)
Boiling point:
639.3±65.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
2-8°C(protect from light)
solubility 
DMSO (Slightly, Heated)
pka
2.02±0.10(Predicted)
form 
Solid
color 
Light Yellow to Yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
F597516
Product name
N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine
Packaging
1g
Price
$80
Updated
2021/12/16
ChemScene
Product number
CS-M2844
Product name
2-Pyrimidinamine,N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-
Purity
99.70%
Packaging
5g
Price
$119
Updated
2021/12/16
Matrix Scientific
Product number
153196
Product name
N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine
Purity
95%
Packaging
5g
Price
$145
Updated
2021/12/16
AK Scientific
Product number
0010AP
Product name
N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine
Packaging
5g
Price
$208
Updated
2021/12/16
Matrix Scientific
Product number
153196
Product name
N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine
Purity
95%
Packaging
25g
Price
$385
Updated
2021/12/16
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N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Chemical Properties,Usage,Production

Uses

N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine functions as a reagent in the synthesis of dihydropyrroloquinoline derivatives with anticancer activity as EGFR modulator to inhibit L858R/T790M.

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine Suppliers

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View Lastest Price from N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine manufacturers

Henan Fengda Chemical Co., Ltd
Product
N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine 1421372-94-2
Price
US $5.00-0.10/KG
Min. Order
1KG
Purity
98%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-09
Henan Aochuang Chemical Co.,Ltd.
Product
N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine 1421372-94-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-16
Career Henan Chemical Co
Product
N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine 1421372-94-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2018-08-15

1421372-94-2, N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMineRelated Search:

AZD-9291 N-(5-Chloro-2-methylphenyl)-7- nitrobenzo[c][1,2,5]oxadiazol-4-amine N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE 1,4-BenzenediaMine, N1-[2-(diMethylaMino)ethyl]-5-Methoxy-N1-Methyl-N4-[4-(1-Methyl-1H-indol-3-yl)-2-pyriMidinyl]-2-nitro- Mutated EGFR-IN-1

  • N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine
  • 2-PyriMidinaMine, N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methyl-1H-indol-3-yl)-
  • N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)-2-pyrimidinamine
  • (4-Fluoro-2-methoxy-5-nitro-phenyl)-[4-(1-methyl-1h-indol-3-yl)-pyrimidin-2-yl]-amine
  • N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-1H-indol-3-yl)pyrimidin-2-amine
  • AZD9291 1
  • OSIMERTINIB INTERMEDIATE 1
  • N-(4-fluoro-2-methoxy-5-nitrophenyl)- 4-(1-methylindol-3-yl)pyrimidin-2-amine(AZD9291 Intermediate 2)
  • EOS-61221
  • N-(4-Fluoro-2-methoxy-5-nitrophenyl)-4-(1-methyl-3-indolyl)-2-pyrimidinamine
  • AZD9291 N-3
  • Osimertinib mesylate intermediate 1
  • AZD9291 Intermediate 2
  • N-(4-fluoro-2-methoxy-5-nitrophenyl)-4-(1-methylindol-3-yl)p...
  • N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine,99%
  • Osimertinib N-3
  • 1421372-94-2
  • AZD9291
  • 1421372-94-2