Ripasudil

Product Name: Ripasudil
CAS No.: 223645-67-8
Chemical Name: Ripasudil
Synonyms: CS-1564;Ripasudil;k115 free base;K-115, Ripasudil;RIPASUDIL HYDROCHLOIDE;RIPASUDIL FREE BASE;K 115 FREE BASE;K115 FREE BASE;(S)-4-Fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline;4-Fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]isoquinoline;Isoquinoline, 4-fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-
CBNumber: CB92722374
Molecular Formula: C15H18FN3O2S
Formula Weight: 323.39
MOL File: 223645-67-8.mol

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Ripasudil Property

Boiling point:: 497.2±55.0 °C(Predicted)
Density: 1.293±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
solubility: Soluble in DMSO
pka: 9.70±0.40(Predicted)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

CSNpharm

Product number: CSN16953
Product name: K-115
Packaging: 5mg
Price: $154
Updated: 2021/12/16

Crysdot

Product number: CD31002611
Product name: K-115freebase
Purity: 98+%
Packaging: 250mg
Price: $515
Updated: 2021/12/16

CSNpharm

Product number: CSN16953
Product name: K-115
Packaging: 25mg
Price: $557
Updated: 2021/12/16

Chemenu

Product number: CM146182
Product name: (S)-4-fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline
Purity: 98%
Packaging: 100mg
Price: $880
Updated: 2021/12/16

Crysdot

Product number: CD31002611
Product name: K-115freebase
Purity: 98+%
Packaging: 1g
Price: $1290
Updated: 2021/12/16

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Ripasudil Chemical Properties,Usage,Production

Description

Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.

Definition

ChEBI: Ripasudil is a member of isoquinolines.

Ripasudil Preparation Products And Raw materials

Raw materials

Preparation Products

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Ripasudil Suppliers

China 43 India 3 United Kingdom 2 United States 6 Global 54

Novachemistry

Tel: 44-20819178-90 02081917890
Fax: (0)2080432064
Email: info@novachemistry.com
Country: United Kingdom
ProdList: 4381
Advantage: 58

Sequoia Research Products Ltd.

Tel: --
Fax: --
Email: sales@seqchem.com
Country: United Kingdom
ProdList: 3113
Advantage: 69

223645-67-8, RipasudilRelated Search:

Ripasudil hydrochloride dihydrate Ripasudil Hydrochloride CAL-101 Temsirolimus Rapamycin Icotinib Radotinib FASUDIL

k115 free base

Ripasudil

4-Fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]isoquinoline

RIPASUDIL FREE BASE;K 115 FREE BASE;K115 FREE BASE

CS-1564

K-115, Ripasudil

Isoquinoline, 4-fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-

RIPASUDIL HYDROCHLOIDE

(S)-4-Fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline

223645-67-8