Ripasudil
- Product Name
- Ripasudil
- CAS No.
- 223645-67-8
- Chemical Name
- Ripasudil
- Synonyms
- CS-1564;Ripasudil;k115 free base;K-115, Ripasudil;RIPASUDIL HYDROCHLOIDE;RIPASUDIL FREE BASE;K 115 FREE BASE;K115 FREE BASE;4-Fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]isoquinoline;Isoquinoline, 4-fluoro-5-[[(2S)-hexahydro-2-methyl-1H-1,4-diazepin-1-yl]sulfonyl]-
- CBNumber
- CB92722374
- Molecular Formula
- C15H18FN3O2S
- Formula Weight
- 323.39
- MOL File
- 223645-67-8.mol
Ripasudil Property
- Boiling point:
- 497.2±55.0 °C(Predicted)
- Density
- 1.293±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- solubility
- Soluble in DMSO
- pka
- 9.70±0.40(Predicted)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- CSN16953
- Product name
- K-115
- Packaging
- 5mg
- Price
- $154
- Updated
- 2021/12/16
- Product number
- CD31002611
- Product name
- K-115freebase
- Purity
- 98+%
- Packaging
- 250mg
- Price
- $515
- Updated
- 2021/12/16
- Product number
- CSN16953
- Product name
- K-115
- Packaging
- 25mg
- Price
- $557
- Updated
- 2021/12/16
- Product number
- CM146182
- Product name
- (S)-4-fluoro-5-((2-methyl-1,4-diazepan-1-yl)sulfonyl)isoquinoline
- Purity
- 98%
- Packaging
- 100mg
- Price
- $880
- Updated
- 2021/12/16
- Product number
- CD31002611
- Product name
- K-115freebase
- Purity
- 98+%
- Packaging
- 1g
- Price
- $1290
- Updated
- 2021/12/16
Ripasudil Chemical Properties,Usage,Production
Description
Ripasudil (Glanatec TM, Kowa Pharmaceutical), a close derivative of fasudil, is another Rho kinase inhibitor approved in Japan at the end of 2014 for the treatment of glaucoma and ocular hypertensionwhen other therapeutic agents are not effective or cannot be administered. Additionally, ripasudil has been tested in diabetic retinopathy clinical trials and shown to promote corneal endothelial cell proliferation, endothelium regeneration, and wound healing.
Definition
ChEBI: Ripasudil is a member of isoquinolines.
Ripasudil Preparation Products And Raw materials
Raw materials
Preparation Products
Ripasudil Suppliers
- Tel
- 44-20819178-90 02081917890
- Fax
- (0)2080432064
- info@novachemistry.com
- Country
- United Kingdom
- ProdList
- 4381
- Advantage
- 58