((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate

Product Name: ((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate
CAS No.: 864070-37-1
Chemical Name: ((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate
Synonyms: (2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol;Empagliflozin-4;Dapagliflozin-009;Jardiance Impurity H;Daglitele Impurity 6;Epaliflozin Ipurity 5;Empagliflozin impurity H;Dapagliflozin Impurity L;Empagliflozin Impurity 5;O-Desethyl Dapagliflozin (>80%)
CBNumber: CB92728624
Molecular Formula: C19H21ClO6
Formula Weight: 380.82
MOL File: 864070-37-1.mol

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((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate Property

Boiling point:: 628.3±55.0 °C(Predicted)
Density: 1.459±0.06 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:1): 0.5 mg/ml
form: A crystalline solid
pka: 10.17±0.15(Predicted)
color: White to off-white
Stability:: Hygroscopic
InChI: InChI=1/C19H21ClO6/c20-14-6-3-11(8-12(14)7-10-1-4-13(22)5-2-10)19-18(25)17(24)16(23)15(9-21)26-19/h1-6,8,15-19,21-25H,7,9H2/t15-,16-,17+,18-,19+/s3
InChIKey: ODQAIMBPQWETBE-YBDYQYBPNA-N
SMILES: O[C@@H]1[C@H]([C@H](O)[C@@H](CO)O[C@H]1C1C=CC(Cl)=C(CC2C=CC(O)=CC=2)C=1)O |&1:1,2,3,5,9,r|

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H319Causes serious eye irritation

H372Causes damage to organs through prolonged or repeated exposure

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

P337+P313IF eye irritation persists: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D290543
Product name: O-DesethylDapagliflozin
Packaging: 5mg
Price: $135
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0010007
Product name: (2S,3R,4R,5S,6R)-2-(4-CHLORO-3-(4-HYDROXYBENZYL)PHENYL)-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-3,4,5-TRIOL
Purity: 95.00%
Packaging: 5MG
Price: $500.83
Updated: 2021/12/16

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((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate Chemical Properties,Usage,Production

Uses

O-Desethyl Dapagliflozin is derivative of antidiabetic drug Dapagliflozin (D185370), which is sodium-glucose transporter 2 inhibitor.

IC 50

SGLT2: 33 nM (IC₅₀)

((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate Suppliers

China 95 India 6 United Kingdom 1 United States 6 Global 108

Beijing Ouhe Technology Co., Ltd

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View Lastest Price from ((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate manufacturers

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Dapagliflozin Impurity 3 864070-37-1
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 10g
Release date: 2024-05-20

ShenZhen H&D Pharmaceutical Technology Co., LTD

Product: Dapagliflozin Impurity 3 864070-37-1
Price: US $0.00/mg
Min. Order: 10mg
Purity: 0.98
Supply Ability: 5g
Release date: 2025-02-13

Guangzhou PI PI BIOTECH INC

Product: Dapagliflozin Impurity 22 864070-37-1
Price: US $0.00-0.00/mg
Min. Order: 10mg
Purity: 90%+
Supply Ability: 10g
Release date: 2022-04-21

864070-37-1, ((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetateRelated Search:

(2S,3R,4S,5S,6R)-2-(3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)-4-chlorophenyl)-tetrahydro-6-(hydroxyMethyl)-2-Methoxy-2H-pyran-3,4,5-triol Empagliflozin Impurity 35 Empagliflozin 2-Chloro-4'-fluorobenzophenone (R)-4-CHLORO-1,3-BUTANEDIOL (2-Chloro-5-iodophenyl)(4-fluorophenyl)methanone Empagliflozin Impurity 23 N/A Dapagliflozin Impurity 20 EMpagliflozin iMpurity 14 Butanoic acid, 4-chloro-3-hydroxy-, (3S)- (3R,4S,5S,6R)-2-[4-chloro-3-[[4-[(3S)-oxolan-3-yl]oxyphenyl]methyl]phenyl]-6-(hydroxymethyl)-2-methoxyoxane-3,4,5-triol Empagliflozin (R)-Isomer Dapagliflozin Impurity 19 D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-, (1R)- Acetoxy Empagliflozin (2S,3R,4S,5S,6R)-2-(4-chloro-3-(4-ethoxybenzyl)phenyl)-6-(hydroxyMethyl)-2-Methoxytetrahydro-2H-pyran-3,4,5-triol GLP-1

Dapagliflozin Impurity L

Empagliflozin-4

Dapagliflozin impurity 12/ O-Desethyl Dapagliflozin/(3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Daglitele Impurity 6

(2S,3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Empagliflozin impurity H

D-Glucitol, 1,5-anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-, (1S)-

Jardiance Impurity H

(3R,4R,5S,6R)-2-(4-chloro-3-(4-hydroxybenzyl)phenyl)-6- (hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol

Dapagliflozin O-Desethyl Impurity

Empagliflozin Destetrahydrofuran Impurity

Empagliflozin Destetrahydrofuran ImpurityQ: What is Empagliflozin Destetrahydrofuran Impurity Q: What is the CAS Number of Empagliflozin Destetrahydrofuran Impurity Q: What is the storage condition of Empagliflozin Destetrahydrofuran Impurity Q: What are the applications of Empagliflozin Destetrahydrofuran Impurity

(2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol

Dapagliflozin-009

Epaliflozin Ipurity 5

1-Chloro-4-(beta-D-glucopyranos-1-yl)-2-(4-hydroxybenzyl)-benzene

(1S)-1,5-Anhydro-1-C-[4-chloro-3-[(4-hydroxyphenyl)methyl]phenyl]-D-glucitol

Empagliflozin Impurity 5

((2R,3S,4R,5R,6S)-6-(4-chloro-3-(4-((S)-tetrahydrofuran-3-yloxy)benzyl)phenyl)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)Methyl acetate

(2S,3R,4R,5S,6R)-2-(4-Chloro-3-(4-hydroxybenzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol (Empagliflozin Impurity)

O-Desethyl Dapagliflozin, 10 mM in DMSO

Empagliflozin Impurity 5(Dapagliflozin Impurity 82)

O-Desethyl Dapagliflozin (>80%)

864070-37-1