ChemicalBook > CAS DataBase List > N,N′-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl-cyclopropanecarboxamide
N,N′-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl-cyclopropanecarboxamide
- Product Name
- N,N′-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl-cyclopropanecarboxamide
- CAS No.
- 329059-55-4
- Chemical Name
- N,N′-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl-cyclopropanecarboxamide
- Synonyms
- BRD7116;BRD7716;BRD-7116;BRD 7116;BRD7116 >=98% (HPLC);BRD7116;BRD-7116;BRD 7116;BRD 7116,Bacterial,BRD7116,inhibit,BRD-7116,Inhibitor;N,N′-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl-cyclopropanecarboxamide;N,N'-(Sulfonylbis(4,1-phenylene))bis(2,2,3,3-tetramethylcyclopropane-1-carboxamide);N,N'-(Sulfonylbis(4,1-phenylene))bis(2,2,3,3-tetramethylcyclopropane-1-carboxamide);Cyclopropanecarboxamide, N,N'-(sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl- (9CI)
- CBNumber
- CB92750612
- Molecular Formula
- C28H36N2O4S
- Formula Weight
- 496.66
- MOL File
- 329059-55-4.mol
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N,N′-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl-cyclopropanecarboxamide Property
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- powder
- color
- white to beige
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
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Safety
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1080
- Product name
- BRD7116
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $105
- Updated
- 2022/05/15
Sigma-Aldrich
- Product number
- SML1080
- Product name
- BRD7116
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $423
- Updated
- 2022/05/15
Cayman Chemical
- Product number
- 20570
- Product name
- BRD7116
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $45
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20570
- Product name
- BRD7116
- Purity
- ≥98%
- Packaging
- 50 mg
- Price
- $382
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 20570
- Product name
- BRD7116
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $28
- Updated
- 2023/01/06
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N,N′-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl-cyclopropanecarboxamide Chemical Properties,Usage,Production
Description
BRD 7116 (329059-55-4) inhibits leukemia stem cell (LSC) activity (EC50 = 200 nM). Displays a >100-fold selectivity for LSCs over normal hematopoietic stem cells.1
Uses
BRD 7116 inhibits LSCe (leukemia stem cell) and HSPCs (Hematopoietic stem cells ), by displaying cell-non-autonomous anti-leukemia activity.
Definition
ChEBI: 2,2,3,3-tetramethyl-N-[4-[4-[[oxo-(2,2,3,3-tetramethylcyclopropyl)methyl]amino]phenyl]sulfonylphenyl]-1-cyclopropanecarboxamide is an anilide.
storage
+4°C
References
1) Hartwell et al. (2013), Niche-based screening identifies small-molecule inhibitors of leukemia stem cells; Nat. Chem. Biol., 9 840
N,N′-(Sulfonyldi-4,1-phenylene)bis[2,2,3,3-tetramethyl-cyclopropanecarboxamide Preparation Products And Raw materials
Raw materials
Preparation Products
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