Description Source Background
ChemicalBook > CAS DataBase List > MOUSE IL-12

MOUSE IL-12

Description Source Background
Product Name
MOUSE IL-12
Chemical Name
MOUSE IL-12
Synonyms
IL-12;RMIL-12;MURINE TSF;MURINE NKSF;MURINE CLMF;MOUSE IL-12;IL-12, MOUSE;MURINE IL-12;p35 elisa kit;Interleukin 12/P
CBNumber
CB9276387
Formula Weight
0
MOL File
Mol file
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MOUSE IL-12 Property

storage temp. 
-20°C
form 
lyophilized powder
biological source
mouse
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Safety

HS Code 
3504009000
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
I8523
Product name
Interleukin-12 from mouse
Purity
≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture
Packaging
10μg
Price
$405.3
Updated
2025/07/31
Apolloscientific
Product number
BITP1164
Product name
rmIL-12
Packaging
100μg
Price
$1376
Updated
2021/12/16
Apolloscientific
Product number
BITP1164
Product name
rmIL-12
Packaging
2μg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
BITP1164
Product name
rmIL-12
Packaging
10μg
Price
$183
Updated
2021/12/16
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MOUSE IL-12 Chemical Properties,Usage,Production

Uses

Interleukin-12 (IL-12) from mouse has been used to study the effect of IL-12 on Th1 (type 1 T helper) immunity in Mongolian gerbils (Meriones unguiculatus) infected with Sporothrix schenckii. It has been used as a standard in ELISA (enzyme-linked immunosorbent assay) cytokine assay.

Biological Activity

Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr (EBV)-transformed B cell lines. IL-12, or Natural Killer Cell Stimulatory Factor (NKSF), is a 75 kDa disulfide-linked heterodimer of a 35 kDa subunit and 40 kDa subunit. IL-12 is produced predominantly by monocytes and NK cells and induces T cells and NK cells to produce IFN-γ. Human IL-12 is not active on mouse cells, but murine IL-12 is active on both murine and human lymphocytes. The biological activity of recombinant human IL-12 was measured by its ability to stimulate the proliferation of PHA-activated human T lymphoblasts. IL-12 has anti-angiogenic properties.

Description

Interleukin-12 Mouse Recombinant produced in HEK 293 cells is a glycosylated disulfide linked heterodimeric polypeptide containing 506 amino acids and having a molecular weight of 75 kDa comprised of disulfide-bonded 35 kDa (p35) and 40 kDa (p40) subunits.
The IL-12 is purified by proprietary chromatographic techniques.

Source

HEK-293 Cells

Background

IL-12 is a heterodimeric cytokine that stimulates the production of IFNgamma from T-cells and natural killer cells, and also induces differentiation of Th1 helper cells. It is an initiator of cell-mediated immunity.

MOUSE IL-12 Preparation Products And Raw materials

Raw materials

Preparation Products

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MOUSE IL-12Related Search:


  • RMIL-12
  • INTERLEUKIN-12, MURINE
  • INTERLEUKIN-12, MOUSE, RECOMBINANT
  • IL-12, MOUSE
  • IL-12
  • INTERLEUKIN-12, MOUSE
  • INTERLEUKIN-12, MOUSE, RECOMBINANT, SPODOPTERA FRUGIPERDA
  • MOUSE INTERLEUKIN 12
  • MOUSE IL-12
  • MURINE CLMF
  • MURINE NKSF
  • MURINE TSF
  • MURINE CTL MATURATION FACTOR
  • MURINE CYTOTOXIC LYMPHOCYTE MATURATION FACTOR
  • MURINE IL-12
  • MURINE INTERLEUKIN-12
  • RECOMBINANT MOUSE IL-12
  • Recombinant Mouse Interleukin-12
  • Interleukin-12 from mouse
  • Interleukin 12/P
  • p35 elisa kit
  • cytokine