MOUSE IL-12
Description Source Background- Product Name
- MOUSE IL-12
- Chemical Name
- MOUSE IL-12
- Synonyms
- IL-12;RMIL-12;MURINE TSF;MURINE NKSF;MURINE CLMF;MOUSE IL-12;IL-12, MOUSE;MURINE IL-12;p35 elisa kit;Interleukin 12/P
- CBNumber
- CB9276387
- Formula Weight
- 0
- MOL File
- Mol file
MOUSE IL-12 Property
- storage temp.
- -20°C
- form
- lyophilized powder
- biological source
- mouse
Safety
- HS Code
- 3504009000
N-Bromosuccinimide Price
- Product number
- I8523
- Product name
- Interleukin-12 from mouse
- Purity
- ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture
- Packaging
- 10μg
- Price
- $405.3
- Updated
- 2025/07/31
- Product number
- BITP1164
- Product name
- rmIL-12
- Packaging
- 100μg
- Price
- $1376
- Updated
- 2021/12/16
- Product number
- BITP1164
- Product name
- rmIL-12
- Packaging
- 2μg
- Price
- $75
- Updated
- 2021/12/16
- Product number
- BITP1164
- Product name
- rmIL-12
- Packaging
- 10μg
- Price
- $183
- Updated
- 2021/12/16
MOUSE IL-12 Chemical Properties,Usage,Production
Uses
Interleukin-12 (IL-12) from mouse has been used to study the effect of IL-12 on Th1 (type 1 T helper) immunity in Mongolian gerbils (Meriones unguiculatus) infected with Sporothrix schenckii. It has been used as a standard in ELISA (enzyme-linked immunosorbent assay) cytokine assay.
Biological Activity
Interleukin-12 (IL-12) was identified as a factor secreted by human Epstein-Barr (EBV)-transformed B cell lines. IL-12, or Natural Killer Cell Stimulatory Factor (NKSF), is a 75 kDa disulfide-linked heterodimer of a 35 kDa subunit and 40 kDa subunit. IL-12 is produced predominantly by monocytes and NK cells and induces T cells and NK cells to produce IFN-γ. Human IL-12 is not active on mouse cells, but murine IL-12 is active on both murine and human lymphocytes. The biological activity of recombinant human IL-12 was measured by its ability to stimulate the proliferation of PHA-activated human T lymphoblasts. IL-12 has anti-angiogenic properties.
Description
Interleukin-12 Mouse Recombinant produced in HEK 293 cells is a glycosylated disulfide linked heterodimeric polypeptide containing 506 amino acids and having a molecular weight of 75 kDa comprised of disulfide-bonded 35 kDa (p35) and 40 kDa (p40) subunits.
The IL-12 is purified by proprietary chromatographic techniques.
Source
HEK-293 Cells
Background
IL-12 is a heterodimeric cytokine that stimulates the production of IFNgamma from T-cells and natural killer cells, and also induces differentiation of Th1 helper cells. It is an initiator of cell-mediated immunity.
MOUSE IL-12 Preparation Products And Raw materials
Raw materials
Preparation Products
MOUSE IL-12 Suppliers
- Tel
- --
- Fax
- --
- jaeger@biotrend.com
- Country
- Germany
- ProdList
- 6115
- Advantage
- 76