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Pyridine sulfur trioxide

Product Name
Pyridine sulfur trioxide
CAS No.
26412-87-3
Chemical Name
Pyridine sulfur trioxide
Synonyms
SULFUR TRIOXIDE PYRIDINE COMPLEX;sulfur trioxide pyridine;PYRIDINE SULFUR TRIOXIDE COMPLEX;NSC 75831;PyridineSO3;fur trioxide;Pyridine suL;TAK438 Impurity 178;Sulfur trioxide pyri;sulfonylideneoxidane
CBNumber
CB9284694
Molecular Formula
C5H5NO3S
Formula Weight
159.16
MOL File
26412-87-3.mol
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Pyridine sulfur trioxide Property

Melting point:
~160 °C
bulk density
600kg/m3
storage temp. 
Store below +30°C.
solubility 
Soluble in polar organic solvents.
form 
Powder
color 
White to beige
Water Solubility 
reacts
Sensitive 
Moisture Sensitive
BRN 
3704116
InChI
InChI=1S/C5H5N.O3S/c1-2-4-6-5-3-1;1-4(2)3/h1-5H;
InChIKey
UDYFLDICVHJSOY-UHFFFAOYSA-N
SMILES
C1=CC=NC=C1.S(=O)(=O)=O
CAS DataBase Reference
26412-87-3(CAS DataBase Reference)
EPA Substance Registry System
Pyridine sulfur trioxide (26412-87-3)
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Safety

Hazard Codes 
C
Risk Statements 
22-34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3261 8/PG 2
WGK Germany 
3
3-10-21
Autoignition Temperature
>350 °C
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29420000
Toxicity
LD50 orally in Rabbit: 500 - 2000 mg/kg
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
84737
Product name
Sulfur trioxide pyridine complex
Purity
technical, ≥45% SO
Packaging
100g
Price
$94.4
Updated
2025/07/31
Sigma-Aldrich
Product number
8.18112
Product name
Sulfur trioxide pyridine complex
Purity
for synthesis
Packaging
100g
Price
$79.9
Updated
2025/07/31
Sigma-Aldrich
Product number
84737
Product name
Sulfur trioxide pyridine complex
Purity
technical, ≥45% SO
Packaging
10g
Price
$21.5
Updated
2022/05/15
TCI Chemical
Product number
P0998
Product name
Pyridine - Sulfur Trioxide Complex
Purity
>95.0%(T)
Packaging
25g
Price
$101
Updated
2025/07/31
TCI Chemical
Product number
P0998
Product name
Pyridine - Sulfur Trioxide Complex
Purity
>95.0%(T)
Packaging
100g
Price
$226
Updated
2025/07/31
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Pyridine sulfur trioxide Chemical Properties,Usage,Production

Chemical Properties

white solid

Uses

Pyridine-Sulfur Trioxide Complex is used in the sulfation of squid ink polysaccharides (SIPs) as a potential candidate compound for the prevention of tumor metastasis. Pyridine-Sulfur Trioxide Complex is also used in the preparation and anticoagulation test of sulfated silk fibroin.

Uses

Usually used for sulfations of alcohols, sulfonations, deoxygenations and other reductions, oxidations with DMSO.

Uses

Sulfur trioxide-pyridine complex is used for sulfations of alcohols, sulfonations, deoxygenations and other reductions, oxidations with dimethyl sulfoxide. It is also used as a source of sulfur trioxide especially in the preparation of sulfate esters. Further, it is used as an activating electrophile in a Parikh-Doering oxidation. In addition to this, it is also used in the preparation and anticoagulation test of sulfated silk fibroin.

reaction suitability

reagent type: oxidant

Purification Methods

Wash the solid with a little CCl4, then H2O to remove traces of pyridine sulfate, and dry it over P2O5. [Baumgarten Chem Ber 59 1166 1926, Olah et al. Synthesis 59 1979, Beilstein 20/5 V 184].

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Pyridine sulfur trioxide Suppliers

NANJING SHUNXIANG PHARMACEUTICAL TECHNOLOGY CO.,LTD.
Tel
025-86819863 13913839793
Fax
025-86819859
Email
sales@jinchemical.com
Country
China
ProdList
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Shandong Xibang Biological Technology Development Co. LTD
Tel
0536-3611186 15063661551
Fax
0536-3611186
Email
196056703@qq.com
Country
China
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Shanghai Worldyang Chemical Co.,Ltd.
Tel
021-021-56795766
Fax
+86-21-56795266
Email
sales@worldyachem.com
Country
China
ProdList
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Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.
Tel
13396369453 QQ3007939906 18678026865
Fax
0536-2101172
Email
sdfantai@163.com
Country
China
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XI'AN VEDA CHEMICAL CO.,LTD
Tel
+86-29-88665278 18392371173
Email
sales@vedachem.com
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China
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Tongling LishidaChem Technology Co., Ltd
Tel
19064063435 18606623089
Email
2236291497@qq.com
Country
China
ProdList
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Quzhou Rundong Chemical (Technology) Co.
Tel
0570-8789886 18892685668
Fax
0570-8789985
Email
info@rundongchemical.com
Country
China
ProdList
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Hubei Zhongshan Medical Technology Co., Ltd
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027-61907345 13397111514
Fax
3443707954
Email
w13397111514@163.com
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China
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J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259138 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
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View Lastest Price from Pyridine sulfur trioxide manufacturers

Nanjing Shunxiang Pharmaceutical Technology Co.,Ltd.
Product
Pyridine sulfur trioxide 26412-87-3
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1
Release date
2025-09-26
Hebei Chuanghai Biotechnology Co., Ltd
Product
Pyridine sulfur trioxide 26412-87-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-11-19
Hebei Junhua Import and Export Co., LTD
Product
Pyridine sulfur trioxide 26412-87-3
Price
US $0.00/kg
Min. Order
1kg
Purity
97%
Supply Ability
1000
Release date
2025-02-24

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