SIR2L
- Product Name
- SIR2L
- Chemical Name
- SIR2L
- Synonyms
- SIRT;SIRT2;SIR2L;SIR2L2;sir2-like 2;Sirtuin 2 human;SIRT2, active, His tagged human
- CBNumber
- CB92919530
- Formula Weight
- 0
- MOL File
- Mol file
SIR2L Property
- storage temp.
- -70°C
- form
- buffered aqueous glycerol solution
- biological source
- human
- Specific Activity
- 6120-10580RLU/min·ng
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P202Do not handle until all safety precautions have been read and understood.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313IF exposed or concerned: Get medical advice/attention.
N-Bromosuccinimide Price
- Product number
- SRP0116
- Product name
- Sirtuin 2 human
- Purity
- recombinant, expressed in <I>E. coli</I>, ≥80% (SDS-PAGE)
- Packaging
- 100 μg
- Price
- $672
- Updated
- 2025/07/31
- Product number
- SRP5271
- Product name
- SIRT2, active, His tagged human
- Purity
- recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution
- Packaging
- 10μG
- Price
- $576
- Updated
- 2023/06/20
- Product number
- 491765
- Product name
- SIRT2
- Packaging
- 100ul
- Price
- $499
- Updated
- 2021/12/16
- Product number
- orb528201
- Product name
- SIRT2
- Packaging
- 10μg
- Price
- $290.7
- Updated
- 2021/12/16
SIR2L Chemical Properties,Usage,Production
Uses
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Biological Activity
Silent information regulator 2 (Sir2) acts as a nicotine adenine dinucleotide (NAD) dependent deacetylase and is implicated in various biological processes such as regulation of transcriptional repression, recombination, the cell-division cycle, microtubule organization, and cellular responses to DNA-damaging agents. In addition, sirtuins also regulate the process involved in aging. Sir2 plays a vital role in mammalian metabolic homeostasis and is considered to be a potent therapeutic target for the treatment of type 2 diabetes. Sir2 has a crucial role in reduction of microglial activation and brain inflammation. Therefore, loss of Sir2 activity increases the risk of susceptibility to neurodegenerative diseases.
SIR2L Preparation Products And Raw materials
Raw materials
Preparation Products
SIR2L Suppliers
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