ChemicalBook > CAS DataBase List > Mal-PEG2-alcohol

Mal-PEG2-alcohol

Product Name
Mal-PEG2-alcohol
CAS No.
34321-81-8
Chemical Name
Mal-PEG2-alcohol
Synonyms
Mal-PEG2-OH;Mal-PEG2-alcohol;TrastuzumabImpurity3;1-[2-(2-Hydroxyethoxy)ethyl]pyrrole-2,5-dione;1-(2-(2-Hydroxyethoxy)ethyl)-1H-pyrrole-2,5-dione;1H-Pyrrole-2,5-dione, 1-[2-(2-hydroxyethoxy)ethyl]-;1-[2-(2-hydroxyethoxy)ethyl]-2,5-dihydro-1H-pyrrole-2,5-dione;Mal-PEG2-OH/1H-Pyrrole-2,5-dione, 1-[2-(2-hydroxyethoxy)ethyl]-
CBNumber
CB93062530
Molecular Formula
C8H11NO4
Formula Weight
185.18
MOL File
34321-81-8.mol
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Mal-PEG2-alcohol Property

Boiling point:
361.7±22.0 °C(Predicted)
Density 
1.317±0.06 g/cm3(Predicted)
storage temp. 
Storage temp. 2-8°C
form 
Solid
pka
14.35±0.10(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P362Take off contaminated clothing and wash before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
M158210
Product name
Mal-PEG2-alcohol
Packaging
10mg
Price
$45
Updated
2021/12/16
BroadPharm
Product number
BP-22341
Product name
Mal-PEG2-alcohol
Purity
98%
Packaging
100mg
Price
$320
Updated
2021/12/16
Apolloscientific
Product number
BIPG1498
Product name
Mal-PEG2-alcohol
Packaging
100mg
Price
$623
Updated
2021/12/16
AK Scientific
Product number
7740BB
Product name
1-(2-(2-Hydroxyethoxy)ethyl)-1H-pyrrole-2,5-dione
Packaging
500mg
Price
$839
Updated
2021/12/16
AK Scientific
Product number
7740BB
Product name
1-(2-(2-Hydroxyethoxy)ethyl)-1H-pyrrole-2,5-dione
Packaging
5g
Price
$2769
Updated
2021/12/16
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Mal-PEG2-alcohol Chemical Properties,Usage,Production

Description

Mal-PEG2-alcohol is a PEG linker containing a maleimide group and a hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The maleimide group will react with a thiol group to form a covalent bond, enabling the connection of biomolecule with a thiol.

Uses

Mal-PEG2-alcohol is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Mal-PEG2-alcohol Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Mal-PEG2-alcohol manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
Mal-PEG2-OH 34321-81-8
Price
US $0.00/g
Min. Order
1g
Purity
>98.00%
Supply Ability
1g
Release date
2024-03-27
Shanghai kingmorn biotechnology Co.,LTD.
Product
Mal-PEG2-alcohol 34321-81-8
Price
US $0.00-0.00/g
Min. Order
100mg
Purity
98%
Supply Ability
>10kg
Release date
2021-07-20

34321-81-8, Mal-PEG2-alcoholRelated Search:

Mal-PEG3-alcohol Mal-PEG3-alcohol Mal-PEG1-acid Mal-PEG2-t-butyl ester Mal-PEG1-t-butyl ester Mal-PEG6-amine TFA salt Mal-PEG4-amine TFA salt Mal-PEG4-propargyl Mal-PEG5-acid Mal-PEG3-NHS ester Mal-PEG6-COOH 1,8-BIS-MALEIMIDOTRIETHYLENEGLYCOL Mal-PEG8-alcohol Mal-PEG8-amine TFA salt Mal-PEG2-Val-Cit-amido-PAB-OH 1-(2-(2-(2-aminoethoxy)ethoxy)ethyl)-1H-pyrrole-2,5-dione Mal-PEG2-NHS ester Mal-PEG2-acid

  • 1-(2-(2-Hydroxyethoxy)ethyl)-1H-pyrrole-2,5-dione
  • Mal-PEG2-alcohol
  • Mal-PEG2-OH
  • 1-[2-(2-hydroxyethoxy)ethyl]-2,5-dihydro-1H-pyrrole-2,5-dione
  • 1H-Pyrrole-2,5-dione, 1-[2-(2-hydroxyethoxy)ethyl]-
  • TrastuzumabImpurity3
  • Mal-PEG2-OH/1H-Pyrrole-2,5-dione, 1-[2-(2-hydroxyethoxy)ethyl]-
  • 1-[2-(2-Hydroxyethoxy)ethyl]pyrrole-2,5-dione
  • 34321-81-8
  • peg