ChemicalBook > CAS DataBase List > 1-Methyl-1H-pyrazole-4-carbaldehyde
1-Methyl-1H-pyrazole-4-carbaldehyde
- Product Name
- 1-Methyl-1H-pyrazole-4-carbaldehyde
- CAS No.
- 25016-11-9
- Chemical Name
- 1-Methyl-1H-pyrazole-4-carbaldehyde
- Synonyms
- 1-METHYL-1H-PYRAZOLE-4-CARBOXALDEHYDE;Pyrazole-4-carboxaldehyde, 1-methyl-;1-Methylpyrazole-4-carbaldehyde;AKOS B000400;AKOS PAO-0259;CHEMBRDG-BB 4301129;IFLAB-BB F2124-0695;TIMTEC-BB SBB000002;ART-CHEM-BB B000400;ASINEX-REAG BAS 00468061
- CBNumber
- CB9307807
- Molecular Formula
- C5H6N2O
- Formula Weight
- 110.11
- MOL File
- 25016-11-9.mol
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1-Methyl-1H-pyrazole-4-carbaldehyde Property
- Melting point:
- 29-34 °C
- Boiling point:
- 60-62°C/0.08mm
- Density
- 1.14±0.1 g/cm3(Predicted)
- Flash point:
- >230 °F
- storage temp.
- Inert atmosphere,2-8°C
- pka
- 0.17±0.10(Predicted)
- form
- powder to lump to clear liquid
- color
- White or Colorless to Yellow to Orange
- Sensitive
- Air Sensitive
- InChI
- InChI=1S/C5H6N2O/c1-7-3-5(4-8)2-6-7/h2-4H,1H3
- InChIKey
- MYFZXSOYJVWTBL-UHFFFAOYSA-N
- SMILES
- N1(C)C=C(C=O)C=N1
- CAS DataBase Reference
- 25016-11-9(CAS DataBase Reference)
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Safety
- Hazard Codes
- Xi
- Risk Statements
- 37/38-41-43
- Safety Statements
- 26-36/37/39
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29331990
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 654043
- Product name
- 1-Methyl-1H-pyrazole-4-carboxaldehyde
- Purity
- 96%
- Packaging
- 1g
- Price
- $39.8
- Updated
- 2023/06/20
TCI Chemical
- Product number
- M2372
- Product name
- 1-Methylpyrazole-4-carboxaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $26
- Updated
- 2024/03/01
TCI Chemical
- Product number
- M2372
- Product name
- 1-Methylpyrazole-4-carboxaldehyde
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $73
- Updated
- 2024/03/01
Alfa Aesar
- Product number
- H54146
- Product name
- 1-Methyl-1H-pyrazole-4-carboxaldehyde, 96%
- Packaging
- 1g
- Price
- $68.65
- Updated
- 2024/03/01
TRC
- Product number
- M330333
- Product name
- 1-Methyl-1H-pyrazole-4-carbaldehyde
- Packaging
- 100mg
- Price
- $75
- Updated
- 2021/12/16
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1-Methyl-1H-pyrazole-4-carbaldehyde Chemical Properties,Usage,Production
Uses
1-Methyl-1H-pyrazole-4-carbaldehyde is a pharmaceutical intermediate used in the synthesis of the CHK1 inhibitor MK-8776.
Synthesis
Using cyclopropyl methyl ketone and dimethoxy-N, N-dimethylmethylamine as starting materials, the target product 1-Methyl-1H-pyrazole-4-carbaldehyde was obtained through aldol condensation, hydrazine condensation cyclization, selective methylation reaction and Vilsmeier-Hack reaction in sequence, with a total yield of up to 48.0%.
1-Methyl-1H-pyrazole-4-carbaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Methyl-1H-pyrazole-4-carbaldehyde manufacturers
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 1-Methyl-1H-pyrazole-4-carbaldehyde 25016-11-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 1-Methyl-1H-pyrazole-4-carbaldehyde 25016-11-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09
Zhuozhou Wenxi import and Export Co., Ltd
- Product
- 1-Methyl-1H-pyrazole-4-carboxaldehyde 25016-11-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-06-27
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