2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
Description- Product Name
- 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
- CAS No.
- 37052-78-1
- Chemical Name
- 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE
- Synonyms
- 5-METHOXY-1H-BENZO[D]IMIDAZOLE-2-THIOL;Omeprazole Impurity A;OMeprazole Related CoMpound B;5-METHOXY-2-BENZIMIDAZOLETHIOL;5-METHOXY-2-MERCAPTOBENZIMIDAZOLE;5-methoxy-1H-benzoimidazole-2-thiol;H 118/87;5-Methoxy;OMEP IM-A;TIMTEC-BB SBB000219
- CBNumber
- CB9313620
- Molecular Formula
- C8H8N2OS
- Formula Weight
- 180.23
- MOL File
- 37052-78-1.mol
2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Property
- Melting point:
- 261-263 °C(lit.)
- Boiling point:
- 309.4±44.0 °C(Predicted)
- Density
- 1.2425 (rough estimate)
- vapor pressure
- 0.001Pa at 25℃
- refractive index
- 1.5690 (estimate)
- storage temp.
- 2-8°C
- solubility
- DMSO (Slightly), Methanol (Sparingly)
- form
- Powder
- pka
- 10.13±0.30(Predicted)
- color
- Off-white to light yellow-brown
- Water Solubility
- insoluble
- Sensitive
- Air Sensitive
- BRN
- 3605123
- LogP
- 1.52-2.399
- CAS DataBase Reference
- 37052-78-1(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-37-22
- Safety Statements
- 26-36
- WGK Germany
- 3
- HazardClass
- IRRITANT
- HS Code
- 29332900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 382485
- Product name
- 5-Methoxy-2-benzimidazolethiol
- Purity
- 99%
- Packaging
- 5g
- Price
- $52.7
- Updated
- 2024/03/01
- Product number
- 1478480
- Product name
- Omeprazole Related Compound B
- Purity
- United States Pharmacopeia (USP) Reference Standard
- Packaging
- 15mg
- Price
- $1380
- Updated
- 2024/03/01
- Product number
- M1256
- Product name
- 2-Mercapto-5-methoxybenzimidazole
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $90
- Updated
- 2024/03/01
- Product number
- B20570
- Product name
- 2-Mercapto-5-methoxybenzimidazole, 99%
- Packaging
- 5g
- Price
- $26.65
- Updated
- 2024/03/01
- Product number
- B20570
- Product name
- 2-Mercapto-5-methoxybenzimidazole, 99%
- Packaging
- 25g
- Price
- $94.3
- Updated
- 2023/06/20
2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Chemical Properties,Usage,Production
Description
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2[[(4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfonyl]-1H-benzimidazole, 5-methoxy-2[[(4-methoxy-3, 5-dimethylpyridin-2-yl-1-oxide) methyl] sulfonyl]-1H-benzimidazole as well as tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate. Furthermore, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole1. Finally, it acts as an intermediate for manufacture of the anti-ulcer drug Omeprazole.
Chemical Properties
off-white to light yellowish-brown powder
Uses
Reagent used in the synthesis of COX-2 inhibitors
Uses
2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.
Uses
5-Methoxy-2-benzimidazolethiol may be used in the preparation of compounds present as contaminants in omeprazole, such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. It may be used in the synthesis of tris[μ-1,2-bis(diphenylphosphino)ethane]-1:2κ2P:P′;1:3κ2P:P′;2:3κ2P:P′-di-μ-bromido-1:2κ4Br:Br-bromido-3κBr-tricopper(I) acetone hemisolvate.
General Description
Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards
Flammability and Explosibility
Not classified
2-MERCAPTO-5-METHOXYBENZIMIDAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE manufacturers
- Product
- 5-Methoxy-2-mercaptobenzimidazole 37052-78-1
- Price
- US $0.00/Kg/Drum
- Min. Order
- 1ASSAYS
- Purity
- 99%
- Supply Ability
- 50mt
- Release date
- 2019-11-01
- Product
- 2-MERCAPTO-5-METHOXYBENZIMIDAZOLE 37052-78-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2021-09-17
- Product
- Esomeprazole Impurity A 37052-78-1
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 0.98
- Supply Ability
- 10g
- Release date
- 2024-05-17