2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER
- Product Name
- 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER
- CAS No.
- 118-57-0
- Chemical Name
- 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER
- Synonyms
- SALOPHEN;Asalphen;Phenestal;Cetosalol;Phenetsal;acetaminosalol;p-Acetamidophenyl salicylate;4-acetamidophenyl salicylate;4-Acetaminophenyl salicylate;ACETYL-P-AMINOPHENYLSALICYLATE
- CBNumber
- CB9322358
- Molecular Formula
- C15H13NO4
- Formula Weight
- 271.27
- MOL File
- 118-57-0.mol
2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER Property
- Melting point:
- 187°
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- LogP
- 2.562 (est)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H317May cause an allergic skin reaction
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P363Wash contaminated clothing before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- S598038
- Product name
- 4-ACETAMIDOPHENYL SALICYLATE
- Purity
- AldrichCPR
- Packaging
- 250MG
- Price
- $179
- Updated
- 2024/03/01
2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER Chemical Properties,Usage,Production
Chemical Properties
solid
Originator
Acetaminosal ,ZYF Pharm Chemical
Uses
Analgesic; antipyretic.
Definition
ChEBI: Acetaminosalol is a carbonyl compound.
Manufacturing Process
2 Methods of producing of acetyl salicylic acid ester of N-acetyl-paminophenol:
1. 65.0 g of N-acetyl-p-aminophenol were slurried with 400 ml of water and
cooled to 10°C. 125 ml of 20% sodium hydroxide were slowly added to the
mixture with stirring, the temperature being maintained 10°-15°C. To the
solution obtained, 75.0 g of acetyl salicylic chloride were added with vigorous
stirring over a period of 0.5 h, the solution being maintained at a temperature of about 10°C. Towards the end of the reaction the pH was checked and
adjusted to greater than 10 by the addition of a small amount of 20% sodium
hydroxide. After all the acid chloride had been added, vigorous stirring was
continued for 0.5 h during which time the crude product separated out. The
acetyl salicylic acid ester of N-acetyl-p-aminophenol was filtered off, washed
thoroughly with water and recrystallised from ethanol.
2. 65.0 g of sodium N-acetyl-p-aminophenol were slurried with 500.0 g of dry
benzene and 80.0 g of acetyl salicylic chloride added. The mixture was heated
under reflux for 4 h and filtered hot. The excess benzene was removed under
vacuum and the crude acetyl salicylic acid ester of N-acetyl-p-aminophenol
crystallized from ethanol.
brand name
Acephen (G & W); Infants’ Feverall (Actavis); Injectapap (Ortho-McNeil); Neopap (Polymedica); Tylenol (McNeil).
Therapeutic Function
Analgesic, Antineuralgic, Antirheumatic, Antipyretic
2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER Suppliers
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View Lastest Price from 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER manufacturers
- Product
- 2-HYDROXYBENZOIC ACID 4-(ACETYLAMINO)PHENYL ESTER 118-57-0
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.9%
- Supply Ability
- 100 Tons Min
- Release date
- 2021-06-16