3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE

Product Name: 3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE
CAS No.: 112192-04-8
Chemical Name: 3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE
Synonyms: Roxindole;RoxindoleHCl;Roxindole [inn];ROXINDOLE HYDROCHLORIDE;1H-Indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-;3-[4-[(3,6-Dihydro-4-phenylpyridin)-1(2H)-yl]butyl]-1H-indol-5-ol;3-[4-(3,6-Dihydro-4-phenylpyridine-1(2H)-yl)butyl]-1H-indole-5-ol;3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE
CBNumber: CB9330973
Molecular Formula: C23H26N2O
Formula Weight: 346.47
MOL File: 112192-04-8.mol

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3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Property

Melting point:: >165°C (dec.)
Boiling point:: 575.7±50.0 °C(Predicted)
Density: 1.173±0.06 g/cm3(Predicted)
storage temp.: Desiccate at -20°C
solubility: DMSO (Slightly), Water (Slightly)
pka: 10.15±0.40(Predicted)
form: Solid
color: Pale Beige to Light Beige
Stability:: Hygroscopic

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 1559
Product name: Roxindolehydrochloride
Purity: ≥98%(HPLC)
Packaging: 10
Price: $181
Updated: 2021/12/16

Tocris

Product number: 1559
Product name: Roxindolehydrochloride
Purity: ≥98%(HPLC)
Packaging: 50
Price: $738
Updated: 2021/12/16

Usbiological

Product number: 256504
Product name: Roxindole hydrochloride
Packaging: 10mg
Price: $423
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0012443
Product name: ROXINDOLE
Purity: 95.00%
Packaging: 5MG
Price: $503.71
Updated: 2021/12/16

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3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

Roxindole Hydrochloride is a selective and potent presynaptic D-2 dopamine autoreceptor agonist.

Definition

ChEBI: Roxindole is a member of indoles. It has a role as an alpha-adrenergic antagonist and a serotonergic drug.

Biological Activity

Dopamine D 2 autoreceptor agonist, with affinity for D 3 , D 4 and 5-HT 1 receptors (pK i values are 8.55, 8.93, 8.23, 9.42, 6.00 and 7.05 for human D 2 , D 3 , D 4 , 5-HT 1A , 5-HT 1B and 5-HT 1D receptors). Inhibits 5-HT uptake and is antidepressant in vivo .

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE Suppliers

China 10 Europe 1 Germany 3 United Kingdom 1 United States 4 Global 19

3B Pharmachem (Wuhan) International Co.,Ltd.

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112192-04-8, 3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDERelated Search:

ROXINDOLE MESYLATE 3-(4-(4-PHENYL-1,2,3,6-TETRAHYDRO-1-PYRIDYL)BUTYL)INDOLE, HCL 1,2,3,6-Tetrahydro-4-phenyl-pyridine 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride 3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE

3-[4-(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)BUTYL]-1H-INDOL-5-OL HYDROCHLORIDE

ROXINDOLE HYDROCHLORIDE

Roxindole

RoxindoleHCl

3-[4-(3,6-Dihydro-4-phenylpyridine-1(2H)-yl)butyl]-1H-indole-5-ol

3-[4-[(3,6-Dihydro-4-phenylpyridin)-1(2H)-yl]butyl]-1H-indol-5-ol

Roxindole [inn]

1H-Indol-5-ol, 3-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-

112192-04-8

Dopamine receptor