Sarsasapogenin

Product Name: Sarsasapogenin
CAS No.: 126-19-2
Chemical Name: Sarsasapogenin
Synonyms: PARIGENIN;PERIGENIN;Sarsagenin;SARSAPOGENIN;Sarsasapogein;SARSAPOGENINE;Sarsasapogenin;Sarsasapogenin;SASARASAPOGENIN;Sarsasapogenin-RM
CBNumber: CB9331677
Molecular Formula: C27H44O3
Formula Weight: 416.64
MOL File: 126-19-2.mol

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Sarsasapogenin Property

Melting point:: 194°C
alpha: D25 -75°; 25546 -89° (c = 0.5 in CHCl3)
Boiling point:: 474.91°C (rough estimate)
Density: 1.0362 (rough estimate)
refractive index: 1.4700 (estimate)
storage temp.: 2-8°C
solubility: DMF: 2 mg/ml; DMSO: 0.2 mg/ml; Ethanol: 2 mg/ml; Ethanol:PBS (pH 7.2)(1:2): 0.3 mg/ml
form: A crystalline solid
pka: 15.14±0.70(Predicted)
color: White to off-white
optical activity: -7525 (c 0.5, CHCl3)
Merck: 13,8456
LogP: 6.210 (est)
CAS DataBase Reference: 126-19-2(CAS DataBase Reference)
NIST Chemistry Reference: Sarsasapogenin(126-19-2)

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Safety

WGK Germany: 3
HS Code: 2932990090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S8534
Product name: Sarsasapogenin
Purity: ≥98%
Packaging: 25mg
Price: $144
Updated: 2025/07/31

Sigma-Aldrich

Product number: S8534
Product name: Sarsasapogenin
Purity: ≥98%
Packaging: 100mg
Price: $418
Updated: 2025/07/31

TCI Chemical

Product number: A3192
Product name: Sarsasapogenin
Packaging: 25MG
Price: $73
Updated: 2025/07/31

TCI Chemical

Product number: A3192
Product name: Sarsasapogenin
Packaging: 100MG
Price: $182
Updated: 2025/07/31

Cayman Chemical

Product number: 24973
Product name: Sarsasapogenin
Purity: ≥95%
Packaging: 25mg
Price: $79
Updated: 2024/03/01

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Sarsasapogenin Chemical Properties,Usage,Production

Description

Smilagengenin is a steroidal saponin with antitumor activity, which is mainly used in refreshing beverages, foaming sweets, mixed wine, etc.

Uses

Sarsasapogenin has cytotoxic properties and is used to develop lead structures for cancer drugs. Sarsasapogenin is also identified to effectively lower the production of Aβ amyloids and stimulate neurite ogrowth in neuronal cell cultures.

Definition

ChEBI: (25S)-5beta-spirostan-3beta-ol is a sapogenin.

in vivo

Sarsasapogenin (20 and 40 mg/kg) significantly restores the sucrose preference deficit induced by olfactory bulbectomy (OB), and increases locomotor activity. Sarsasapogenin groups (20 and 40 mg/kg) have significantly lower immobility times, higher AChE protein expression levels than the OB group. Furthermore, Sarsasapogenin (20 and 40 mg/kg) groups have significantly higher α7-nAChR protein expression, and increases higher α4-nAChR protein expression levels compared to rats in the OB group^[2]. Sarsasapogenin (5 or 10 mg/kg, p.o.) inhibits TNBS-induced colon shortening and myeloperoxidase activity in mice, reducing NF-κB activation and interleukin (IL)-1β, tumor necrosis factor (TNF)-α, and IL-6 levels, while simultaneously increasing IL-10^[3].

IC 50

NF-κB

Sarsasapogenin Preparation Products And Raw materials

Raw materials

Preparation Products

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Sarsasapogenin Suppliers

China 257 China Hong Kong 1 Europe 3 France 1 Germany 4 India 3 Japan 2 Switzerland 1 United Kingdom 7 United States 25 Global 304

Chengdu Biopurify Ltd.

Tel: 28-82633860 18982077548
Email: cwb1@biopurify.cn
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Aktin Chemicals, Inc.

Tel: 028-85159085
Email: info@aktinchem.com
Country: China
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Naturewill Biotechnology Co., Ltd.

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Shanghai Zhiyun Biotechnology Co., Ltd

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Country: China
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RENI Pharmaceutical Technology Co., Ltd

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Email: 2881944542@qq.com
Country: China
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J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
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Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
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Syntechem Co.,Ltd

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Email: info@syntechem.com
Country: China
ProdList: 12984
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View Lastest Price from Sarsasapogenin manufacturers

Shaanxi Dideu New Materials Co. Ltd

Product: Sarsasapogenin 126-19-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-11-24

Changsha Staherb Natural Ingredients Co., Ltd.

Product: Sarsasapogenin 126-19-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: ≥98% HPLC
Supply Ability: 1000kg
Release date: 2022-10-11

Changsha Staherb Natural Ingredients Co., Ltd.

Product: Sarsasapogenin 126-19-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: ≥98% HPLC
Supply Ability: 1000kg
Release date: 2022-10-11

126-19-2, SarsasapogeninRelated Search:

Saponin Timosaponin BII Timosaponin A-III isomangiferin Mangiferin Sarsasapogenin 3-O-β-D-galactopyranosid Officinalisinin I Poly(vinyl alcohol) Ethanol Asiaticoside Oridonin Geniposide SMILAGENIN Epi-sarsasapogenin COPROSTANOL COPROSTANE Spirostan-3-ol Sarsasapogenin

Spirostan-3-ol, (3β,5β,25S)-

Sarsasapogenin baqia

Spirostan-3-ol, (3b,5b,25S)-

PARIGENIN;SARSAGENIN

Sarsagenin

Sarsasapogein

SARSASAPOGENIN; PARIGENIN

SASARASAPOGENIN 98.0% BY HPLC

(25S)-3β-Hydroxy-5β-spirostane

Sarsasapogenin,(25S)-Spirostan-3β-ol, Parigenin

(25S)-Spirostan-3β-ol

(2aR,2'R,4S,5'S,6aS,6bS,8aS,8bR,9S,11aS,12aS,12bR)-5',6a,8a,9-tetraMethyldocosahydrospiro[naphtho[2',1':4,5]indeno[2,1-b]furan-10,2'-pyran]-4-ol

5-BETA, 20-ALPHA, 22-BETA, 25L-SPIROSTAN-3-BETA-OL

[25S]-SPIROSTAN-3BETA-OL

(25s)-spirostan-3b-ol

25S,5ALPHA-SPIROSTAN-3BETA-OL

(25S)-5BETA-SPIROSTAN-3BETA-OL

SASARASAPOGENIN

SARSAPOGENIN

SARSAPOGENINE

PARIGENIN

PERIGENIN

Sarsasapogenin

(25S)-Spirostan-3beta-ol, Parigenin

(25S)-Spirostan-3β-ol, Parigenin

Yucca foam extract

(25S)-5β-spirostan-3β-ol

(3beta,5beta,25S)-Spirostan-3-ol

Sarsasapogenin-RM

Azithromycin Impurity 67

Sarsasapogenin

126-19-2

chemical reagent

pharmaceutical intermediate

phytochemical

reference standards from Chinese medicinal herbs (TCM).

Steroids

Inhibitors

standardized herbal extract

hormone