Clinofibrate

Product Name: Clinofibrate
CAS No.: 30299-08-2
Chemical Name: Clinofibrate
Synonyms: S 8527;lipoclin;bis(oxy);CLINOFIBRATE;Clinofibrate >CLINOFIBRATE (S-8527);Clinofibrate USP/EP/BP;2,2'-(cyclohexyliden...;CLINOFIBRATE(FORR&DONLY);bis(2-methylbutanoic acid)
CBNumber: CB9333525
Molecular Formula: C28H36O6
Formula Weight: 468.58
MOL File: 30299-08-2.mol

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Clinofibrate Property

Melting point:: 143-145°C
Boiling point:: 498.6°C (rough estimate)
Density: 1.1005 (rough estimate)
refractive index: 1.4482 (estimate)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Sligthly)
form: Solid
pka: 3.00±0.10(Predicted)
color: White to Off-White
Merck: 14,2357
CAS DataBase Reference: 30299-08-2(CAS DataBase Reference)

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Safety

RTECS: ES8900000
HS Code: 2918.99.4700

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical

Product number: C3100
Product name: Clinofibrate
Purity: >98.0%(HPLC)
Packaging: 200mg
Price: $93
Updated: 2024/03/01

TCI Chemical

Product number: C3100
Product name: Clinofibrate
Purity: >98.0%(HPLC)
Packaging: 1g
Price: $282
Updated: 2024/03/01

TRC

Product number: C580100
Product name: Clinofibrate
Packaging: 5mg
Price: $50
Updated: 2021/12/16

TRC

Product number: C580100
Product name: Clinofibrate
Packaging: 100mg
Price: $590
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC20487
Product name: Clinofibrate
Packaging: 50mg
Price: $841.5
Updated: 2021/12/16

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Clinofibrate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Lipocrin,Sumitomo,Japan,1981

Uses

Clinofibrate is an antilipemic, used as an anti-atherosclerosis agent.

Definition

ChEBI: Clinofibrate is an organic molecular entity.

Manufacturing Process

Into a mixture of 6.0 g of a bishydroxyphenyl derivative, and 44.0 g of methyl ethyl ketone was added 16.2 g of crushed potassium hydroxide or sodium hydroxide. Chloroform was added dropwise into the above mixture with stirring at 20°C to 80°C, and the resultant mixture was heated for 20 hours under reflux to complete the reaction. Thereafter the reaction mixture was concentrated to give a residue. Into the residue was added water. After cooling, the resultant mixture was treated with activated charcoal and acidified by diluted hydrochloric acid or sulfuric acid to give an oily substance. The oily substance was extracted by ether and the ether solution was contacted with aqueous diluted Na2CO3 solution. The separated aqueous layer was washed with ether, acidified and again extracted with ether. The obtained ester layer was dried over anhydrous sodium sulfate and concentrated to give 1.0 g of a crude product which was purified by recrystallization or chromatography, to give crystals MP 143°C to 146°C (decomp.)

Therapeutic Function

Antihyperlipoproteinemic

Clinofibrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Clinofibrate Suppliers

Americas 1 Canada 1 China 124 Europe 1 Germany 1 India 2 Japan 1 United Kingdom 5 United States 22 Global 158

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 94838
Advantage: 76

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10194
Advantage: 62

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: zhangsn@titansci.com
Country: China
ProdList: 14113
Advantage: 59

LGM Pharma

Tel: 1-(800)-881-8210
Fax: 615-250-9817
Email: inquiries@lgmpharma.com
Country: United States
ProdList: 2127
Advantage: 70

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9816
Advantage: 59

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 0712-0712-2580635 15527768850
Email: 1791901229@qq.com
Country: China
ProdList: 8849
Advantage: 52

Wisdom Pharmaceutical Co., Ltd.

Tel: 0086-15189180296
Fax: 0086-513-81292226
Email: l_xu@wisdompharma.com
Country: China
ProdList: 221
Advantage: 60

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View Lastest Price from Clinofibrate manufacturers

Dideu Industries Group Limited

Product: Clinofibrate 30299-08-2
Price: US $1.10/g
Min. Order: 1g
Purity: 99.9%
Supply Ability: 100 Tons min
Release date: 2021-08-05

Shaanxi Dideu Medichem Co. Ltd

Product: Clinofibrate 30299-08-2
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 500 MT
Release date: 2020-05-11

Career Henan Chemical Co

Product: Clinofibrate 30299-08-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1000KG
Release date: 2019-08-31

30299-08-2, ClinofibrateRelated Search:

Paraquat dichloride Methyl acetate Basic Violet 1 Butyric Acid Methanol Acetonitrile Methyl acrylate Methylparaben Bezafibrate Kresoxim-methyl lifibrate Methyl 4,4'-Cyclohexylidenebisphenol 4-TERT-BUTYLPHENOXYACETIC ACID 4,4'-ISOPROPYLIDENEBIS(2-PHENOXYETHANOL) 2-Phenoxybutyric acid (S)-(+)-2-Methylbutyric acid Methylbutyric acid

CLINOFIBRATE (S-8527)

2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis(2-methylbutyricacid)

lipoclin

2,2'-(cyclohexylidenebis(4,1-phenyleneoxy))bis(2-methyl)-butanoic acid

CLINOFIBRATE

CLINOFIBRATE(FORR&DONLY)

1,1-Bis[4'-(1''-carboxy-1''-methylpropoxy)phenyl]cyclohexane

Butanoic acid, 2,2'-[cyclohexylidenebis(4,1-phenyleneoxy)]bis[2-methyl-

S 8527

2,2'-[(1,1-Cyclohexanediyl)bis(4,1-phenyleneoxy)]bis(2-methylbutanoic acid)

2,2'-[Cyclohexylidenebis(4,1-phenyleneoxy)]bis(2-methylbutyric acid)

2,2'-(cyclohexyliden...

2,2,-((cyclohexane-1,1-diylbis(4,1-phenylene))bis(oxy))bis(2-methylbutanoic acid)

2,2'-((Cyclohexane-1,1-diylbis(4,1-phenylene)

bis(2-methylbutanoic acid)

bis(oxy)

2,2’-(4,4’-cyclohexylidenediphenoxy)-2,2’-dimethyldibutyricacid

2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis-(2-methyl-butyricaci

Clinofibrate &gt

2,2'-(4,4'-Cyclohexylidenediphenoxy)-2,2'-dimethyldibutanoic Acid

Clinofibrate USP/EP/BP

Clinofibrate (10mM in DMSO)

2,2’-[[Cyclohexane-1,1-diylbis(4,1-phenylene)]bis(oxy)]bis(2-methylbutanoic Acid)

30299-08-2

30298-08-2

C28H36O6

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Aromatics

Intermediates & Fine Chemicals

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