ChemicalBook > CAS DataBase List > Clinofibrate

Clinofibrate

Product Name
Clinofibrate
CAS No.
30299-08-2
Chemical Name
Clinofibrate
Synonyms
S 8527;lipoclin;bis(oxy);CLINOFIBRATE;Clinofibrate >CLINOFIBRATE (S-8527);Clinofibrate USP/EP/BP;2,2'-(cyclohexyliden...;CLINOFIBRATE(FORR&DONLY);bis(2-methylbutanoic acid)
CBNumber
CB9333525
Molecular Formula
C28H36O6
Formula Weight
468.58
MOL File
30299-08-2.mol
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Clinofibrate Property

Melting point:
143-145°C
Boiling point:
498.6°C (rough estimate)
Density 
1.1005 (rough estimate)
refractive index 
1.4482 (estimate)
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform (Slightly), Methanol (Sligthly)
form 
Solid
pka
3.00±0.10(Predicted)
color 
White to Off-White
Merck 
14,2357
CAS DataBase Reference
30299-08-2(CAS DataBase Reference)
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Safety

RTECS 
ES8900000
HS Code 
2918.99.4700
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TCI Chemical
Product number
C3100
Product name
Clinofibrate
Purity
>98.0%(HPLC)
Packaging
200mg
Price
$93
Updated
2024/03/01
TCI Chemical
Product number
C3100
Product name
Clinofibrate
Purity
>98.0%(HPLC)
Packaging
1g
Price
$282
Updated
2024/03/01
TRC
Product number
C580100
Product name
Clinofibrate
Packaging
5mg
Price
$50
Updated
2021/12/16
TRC
Product number
C580100
Product name
Clinofibrate
Packaging
100mg
Price
$590
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC20487
Product name
Clinofibrate
Packaging
50mg
Price
$841.5
Updated
2021/12/16
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Clinofibrate Chemical Properties,Usage,Production

Chemical Properties

White Solid

Originator

Lipocrin,Sumitomo,Japan,1981

Uses

Clinofibrate is an antilipemic, used as an anti-atherosclerosis agent.

Definition

ChEBI: Clinofibrate is an organic molecular entity.

Manufacturing Process

Into a mixture of 6.0 g of a bishydroxyphenyl derivative, and 44.0 g of methyl ethyl ketone was added 16.2 g of crushed potassium hydroxide or sodium hydroxide. Chloroform was added dropwise into the above mixture with stirring at 20°C to 80°C, and the resultant mixture was heated for 20 hours under reflux to complete the reaction. Thereafter the reaction mixture was concentrated to give a residue. Into the residue was added water. After cooling, the resultant mixture was treated with activated charcoal and acidified by diluted hydrochloric acid or sulfuric acid to give an oily substance. The oily substance was extracted by ether and the ether solution was contacted with aqueous diluted Na2CO3 solution. The separated aqueous layer was washed with ether, acidified and again extracted with ether. The obtained ester layer was dried over anhydrous sodium sulfate and concentrated to give 1.0 g of a crude product which was purified by recrystallization or chromatography, to give crystals MP 143°C to 146°C (decomp.)

Therapeutic Function

Antihyperlipoproteinemic

Clinofibrate Preparation Products And Raw materials

Raw materials

Preparation Products

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Clinofibrate Suppliers

J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Chembest Research Laboratories Limited
Tel
+86-21-20908456
Fax
021-58180499
Email
sales@BioChemBest.com
Country
China
ProdList
6005
Advantage
61
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Pure Chemistry Scientific Inc.
Tel
001-857-928-2050 or 1-888-588-9418
Fax
001-617-206-9595
Email
sales@chemreagents.com
Country
United States
ProdList
10186
Advantage
62
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
LGM Pharma
Tel
1-(800)-881-8210
Fax
615-250-9817
Email
inquiries@lgmpharma.com
Country
United States
ProdList
2123
Advantage
70
Shanghai Longsheng chemical Co.,Ltd.
Tel
021-58099652-8005 13585536065
Fax
021-58099609
Email
bin.wu@shlschem.com
Country
China
ProdList
9809
Advantage
59
Chemsky(shanghai)International Co.,Ltd.
Tel
021-50135380
Email
shchemsky@sina.com
Country
China
ProdList
32321
Advantage
50
XiaoGan ShenYuan ChemPharm co,ltd
Tel
15527768850
Email
1791901229@qq.com
Country
China
ProdList
8836
Advantage
52
Wisdom Pharmaceutical Co., Ltd.
Tel
0086-15189180296
Fax
0086-513-81292226
Email
l_xu@wisdompharma.com
Country
China
ProdList
221
Advantage
60
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View Lastest Price from Clinofibrate manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Clinofibrate 30299-08-2
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
500 MT
Release date
2020-05-11
Career Henan Chemical Co
Product
Clinofibrate 30299-08-2
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1000KG
Release date
2019-08-31

30299-08-2, ClinofibrateRelated Search:


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  • CLINOFIBRATE
  • CLINOFIBRATE(FORR&DONLY)
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  • 2,2'-(cyclohexyliden...
  • 2,2,-((cyclohexane-1,1-diylbis(4,1-phenylene))bis(oxy))bis(2-methylbutanoic acid)
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  • bis(2-methylbutanoic acid)
  • bis(oxy)
  • 2,2’-(4,4’-cyclohexylidenediphenoxy)-2,2’-dimethyldibutyricacid
  • 2,2’-cyclohexane-1,1-diylbis(p-phenyleneoxy)bis-(2-methyl-butyricaci
  • Clinofibrate &gt
  • 2,2'-(4,4'-Cyclohexylidenediphenoxy)-2,2'-dimethyldibutanoic Acid
  • Clinofibrate USP/EP/BP
  • Clinofibrate (10mM in DMSO)
  • 2,2’-[[Cyclohexane-1,1-diylbis(4,1-phenylene)]bis(oxy)]bis(2-methylbutanoic Acid)
  • 30299-08-2
  • 30298-08-2
  • C28H36O6
  • API
  • Inhibitors
  • Aromatics
  • Intermediates & Fine Chemicals
  • Pharmaceuticals