Clinofibrate
- Product Name
- Clinofibrate
- CAS No.
- 30299-08-2
- Chemical Name
- Clinofibrate
- Synonyms
- S 8527;lipoclin;bis(oxy);CLINOFIBRATE;Clinofibrate >CLINOFIBRATE (S-8527);Clinofibrate USP/EP/BP;2,2'-(cyclohexyliden...;CLINOFIBRATE(FORR&DONLY);bis(2-methylbutanoic acid)
- CBNumber
- CB9333525
- Molecular Formula
- C28H36O6
- Formula Weight
- 468.58
- MOL File
- 30299-08-2.mol
Clinofibrate Property
- Melting point:
- 143-145°C
- Boiling point:
- 498.6°C (rough estimate)
- Density
- 1.1005 (rough estimate)
- refractive index
- 1.4482 (estimate)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Slightly), Methanol (Sligthly)
- form
- Solid
- pka
- 3.00±0.10(Predicted)
- color
- White to Off-White
- Merck
- 14,2357
- CAS DataBase Reference
- 30299-08-2(CAS DataBase Reference)
Safety
- RTECS
- ES8900000
- HS Code
- 2918.99.4700
N-Bromosuccinimide Price
- Product number
- C3100
- Product name
- Clinofibrate
- Purity
- >98.0%(HPLC)
- Packaging
- 200mg
- Price
- $93
- Updated
- 2024/03/01
- Product number
- C3100
- Product name
- Clinofibrate
- Purity
- >98.0%(HPLC)
- Packaging
- 1g
- Price
- $282
- Updated
- 2024/03/01
- Product number
- C580100
- Product name
- Clinofibrate
- Packaging
- 5mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- C580100
- Product name
- Clinofibrate
- Packaging
- 100mg
- Price
- $590
- Updated
- 2021/12/16
- Product number
- CS-6464
- Product name
- Clinofibrate
- Purity
- 99.70%
- Packaging
- 5mg
- Price
- $60
- Updated
- 2021/12/16
Clinofibrate Chemical Properties,Usage,Production
Chemical Properties
White Solid
Originator
Lipocrin,Sumitomo,Japan,1981
Uses
Clinofibrate is an antilipemic, used as an anti-atherosclerosis agent.
Definition
ChEBI: Clinofibrate is an organic molecular entity.
Manufacturing Process
Into a mixture of 6.0 g of a bishydroxyphenyl derivative, and 44.0 g of methyl ethyl ketone was added 16.2 g of crushed potassium hydroxide or sodium hydroxide. Chloroform was added dropwise into the above mixture with stirring at 20°C to 80°C, and the resultant mixture was heated for 20 hours under reflux to complete the reaction. Thereafter the reaction mixture was concentrated to give a residue. Into the residue was added water. After cooling, the resultant mixture was treated with activated charcoal and acidified by diluted hydrochloric acid or sulfuric acid to give an oily substance. The oily substance was extracted by ether and the ether solution was contacted with aqueous diluted Na2CO3 solution. The separated aqueous layer was washed with ether, acidified and again extracted with ether. The obtained ester layer was dried over anhydrous sodium sulfate and concentrated to give 1.0 g of a crude product which was purified by recrystallization or chromatography, to give crystals MP 143°C to 146°C (decomp.)
Therapeutic Function
Antihyperlipoproteinemic
Clinofibrate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Clinofibrate manufacturers
- Product
- Clinofibrate 30299-08-2
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 500 MT
- Release date
- 2020-05-11
- Product
- Clinofibrate 30299-08-2
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000KG
- Release date
- 2019-08-31