ChemicalBook > CAS DataBase List > 2,5-dioxopyrrolidin-1-yl pent-4-ynoate

2,5-dioxopyrrolidin-1-yl pent-4-ynoate

Product Name
2,5-dioxopyrrolidin-1-yl pent-4-ynoate
CAS No.
132178-37-1
Chemical Name
2,5-dioxopyrrolidin-1-yl pent-4-ynoate
Synonyms
Propargyl-C1-NHS ester;Succinimidyl 4-Pentynoate;4-Pentynoic acid NHS ester;4-Pentynoic acid succinimidyl ester;2,5-dioxopyrrolidin-1-yl pent-4-ynoate;4-Pentynoic acid, 2,5-dioxo-1-pyrrolidinyl ester;inhibit,Propargyl C1 NHS ester,PropargylC1NHS ester,Inhibitor,Antibody-drug conjugates linkers,ADC Linkers,Propargyl-C-1-NHS ester
CBNumber
CB93376750
Molecular Formula
C9H9NO4
Formula Weight
195.17
MOL File
132178-37-1.mol
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2,5-dioxopyrrolidin-1-yl pent-4-ynoate Property

Melting point:
71 °C
Boiling point:
301.7±44.0 °C(Predicted)
Density 
1.31±0.1 g/cm3(Predicted)
storage temp. 
-20°C, sealed storage, away from moisture and light
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
P227528
Product name
Succinimidyl4-Pentynoate
Packaging
10mg
Price
$265
Updated
2021/12/16
ChemScene
Product number
CS-0105047
Product name
Propargyl-C1-NHSester
Purity
95.12%
Packaging
100mg
Price
$276
Updated
2021/12/16
Activate Scientific
Product number
AS113018
Product name
4-Pentynoic acid succinimidyl ester
Purity
95+%
Packaging
100mg
Price
$345
Updated
2021/12/16
Activate Scientific
Product number
AS113018
Product name
4-Pentynoic acid succinimidyl ester
Purity
95+%
Packaging
250mg
Price
$632
Updated
2021/12/16
ChemScene
Product number
CS-0105047
Product name
Propargyl-C1-NHSester
Purity
95.12%
Packaging
500mg
Price
$828
Updated
2021/12/16
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2,5-dioxopyrrolidin-1-yl pent-4-ynoate Chemical Properties,Usage,Production

Uses

Propargyl-C1-NHS ester is a nonclaevable linker for antibody-agent-conjugation (ADC). Propargyl-C1-NHS ester is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

Non-cleavable Linker

2,5-dioxopyrrolidin-1-yl pent-4-ynoate Preparation Products And Raw materials

Raw materials

Preparation Products

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2,5-dioxopyrrolidin-1-yl pent-4-ynoate Suppliers

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132178-37-1, 2,5-dioxopyrrolidin-1-yl pent-4-ynoateRelated Search:


  • 2,5-dioxopyrrolidin-1-yl pent-4-ynoate
  • 4-Pentynoic acid NHS ester
  • Propargyl-C1-NHS ester
  • 4-Pentynoic acid succinimidyl ester
  • 4-Pentynoic acid, 2,5-dioxo-1-pyrrolidinyl ester
  • Succinimidyl 4-Pentynoate
  • inhibit,Propargyl C1 NHS ester,PropargylC1NHS ester,Inhibitor,Antibody-drug conjugates linkers,ADC Linkers,Propargyl-C-1-NHS ester
  • 132178-37-1