1-Acetylimidazole
- Product Name
- 1-Acetylimidazole
- CAS No.
- 2466-76-4
- Chemical Name
- 1-Acetylimidazole
- Synonyms
- NAI;1-(1H-imidazol-1-yl)ethan-1-one;Acetylimidazole;4-ACETYLIMIDAZOLE;1-Imidazol-1-ylethanone;1-Acetylimida;N-ACETYLIMIDAZOL;1-AcetliMidazole;1-acetyl-imidazol;N-ACETYLIMIDAZOLE
- CBNumber
- CB9339608
- Molecular Formula
- C5H6N2O
- Formula Weight
- 110.11
- MOL File
- 2466-76-4.mol
1-Acetylimidazole Property
- Melting point:
- 99-105 °C (lit.)
- Boiling point:
- 206.4°C (rough estimate)
- Density
- 1.2111 (rough estimate)
- refractive index
- 1.4800 (estimate)
- storage temp.
- 2-8°C
- solubility
- water: soluble50mg/mL, clear, colorless
- pka
- pKa 3.6(H2O,t = 25,I=0.2) (Uncertain)
- form
- Adhering Crystals or Crystalline Powder
- color
- White to beige or light tan
- Water Solubility
- Hydrolyzes in water. Solubility in methanol (almost transparency).
- Sensitive
- Moisture Sensitive
- BRN
- 108425
- Stability:
- Moisture Sensitive
- CAS DataBase Reference
- 2466-76-4(CAS DataBase Reference)
- NIST Chemistry Reference
- 1H-Imidazole, 1-acetyl-(2466-76-4)
- EPA Substance Registry System
- 1H-Imidazole, 1-acetyl- (2466-76-4)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 8.51210
- Product name
- 1-Acetylimidazole
- Purity
- Novabiochem?
- Packaging
- 25G
- Price
- $27.2
- Updated
- 2024/03/01
- Product number
- 157864
- Product name
- 1-Acetylimidazole
- Purity
- 98%
- Packaging
- 25g
- Price
- $53.1
- Updated
- 2024/03/01
- Product number
- 8.51210
- Product name
- 1-Acetylimidazole
- Purity
- Novabiochem?
- Packaging
- 100G
- Price
- $97.1
- Updated
- 2024/03/01
- Product number
- 157864
- Product name
- 1-Acetylimidazole
- Purity
- 98%
- Packaging
- 1kg
- Price
- $467.4
- Updated
- 2024/03/01
- Product number
- A0694
- Product name
- N-Acetylimidazole
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $97
- Updated
- 2024/03/01
1-Acetylimidazole Chemical Properties,Usage,Production
Chemical Properties
white to beige or light tan adhering crystals or
Uses
Acetylating agent for capping unreacted amino groups in peptide synthesis.
Uses
It is a mild acylating agent and its reactivity can be enhanced by quaternization with, e.g. benzyl bromide. 1-Acetylimidazole was used as acetylation reagent for amino groups. It was also employed for acetylation of histones. It is relatively specific reagent for tyrosyl residue acetylatioa dn a reagent used in the synthesis of annulated imidazole derivatives.
Uses
Relatively specific reagent for tyrosyl residue acetylation. Reagent used in the synthesis of annulated imidazole derivatives.
Definition
ChEBI: N-acetylimidazole is a N-acylimidazole.
General Description
Rate of solvolysis of 1-acetylimidazole in acid solutions was evaluated. Reaction of 1-acetylimidazole with orthophosphate and adenosine-5′-phosphate has been reported.
Purification Methods
It is recrystallised from isopropenyl acetate and dried in a vacuum over P2O5. [Riordan & Valee Methods Enzymol 25 500 1972, Beilstein 23/4 V 218.]
1-Acetylimidazole Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 1-Acetylimidazole manufacturers
- Product
- 1-Acetylimidazole 2466-76-4
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-08-08
- Product
- 1-Acetylimidazole 2466-76-4
- Price
- US $6.00/kg
- Min. Order
- 1kg
- Purity
- More than 99%
- Supply Ability
- 2000KG/Month
- Release date
- 2024-04-28
- Product
- 1-Acetylimidazole 2466-76-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 1000000
- Release date
- 2023-12-21