ChemicalBook > CAS DataBase List > 1-Acetylimidazole

1-Acetylimidazole

Product Name
1-Acetylimidazole
CAS No.
2466-76-4
Chemical Name
1-Acetylimidazole
Synonyms
NAI;1-(1H-imidazol-1-yl)ethan-1-one;Acetylimidazole;4-ACETYLIMIDAZOLE;1-Imidazol-1-ylethanone;1-Acetylimida;N-ACETYLIMIDAZOL;1-AcetliMidazole;1-acetyl-imidazol;N-ACETYLIMIDAZOLE
CBNumber
CB9339608
Molecular Formula
C5H6N2O
Formula Weight
110.11
MOL File
2466-76-4.mol
More
Less

1-Acetylimidazole Property

Melting point:
99-105 °C (lit.)
Boiling point:
206.4°C (rough estimate)
Density 
1.2111 (rough estimate)
refractive index 
1.4800 (estimate)
storage temp. 
2-8°C
solubility 
water: soluble50mg/mL, clear, colorless
pka
pKa 3.6(H2O,t = 25,I=0.2) (Uncertain)
form 
Adhering Crystals or Crystalline Powder
color 
White to beige or light tan
Water Solubility 
Hydrolyzes in water. Solubility in methanol (almost transparency).
Sensitive 
Moisture Sensitive
BRN 
108425
Stability:
Moisture Sensitive
CAS DataBase Reference
2466-76-4(CAS DataBase Reference)
NIST Chemistry Reference
1H-Imidazole, 1-acetyl-(2466-76-4)
EPA Substance Registry System
1H-Imidazole, 1-acetyl- (2466-76-4)
More
Less

Safety

Risk Statements 
36/37/38
Safety Statements 
24/25
WGK Germany 
3
RTECS 
NI3400000
10-21
TSCA 
Yes
HS Code 
29332900
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.51210
Product name
1-Acetylimidazole
Purity
Novabiochem?
Packaging
25G
Price
$27.2
Updated
2024/03/01
Sigma-Aldrich
Product number
157864
Product name
1-Acetylimidazole
Purity
98%
Packaging
25g
Price
$53.1
Updated
2024/03/01
Sigma-Aldrich
Product number
8.51210
Product name
1-Acetylimidazole
Purity
Novabiochem?
Packaging
100G
Price
$97.1
Updated
2024/03/01
Sigma-Aldrich
Product number
157864
Product name
1-Acetylimidazole
Purity
98%
Packaging
1kg
Price
$467.4
Updated
2024/03/01
TCI Chemical
Product number
A0694
Product name
N-Acetylimidazole
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$97
Updated
2024/03/01
More
Less

1-Acetylimidazole Chemical Properties,Usage,Production

Chemical Properties

white to beige or light tan adhering crystals or

Uses

Acetylating agent for capping unreacted amino groups in peptide synthesis.

Uses

It is a mild acylating agent and its reactivity can be enhanced by quaternization with, e.g. benzyl bromide. 1-Acetylimidazole was used as acetylation reagent for amino groups. It was also employed for acetylation of histones. It is relatively specific reagent for tyrosyl residue acetylatioa dn a reagent used in the synthesis of annulated imidazole derivatives.

Uses

Relatively specific reagent for tyrosyl residue acetylation. Reagent used in the synthesis of annulated imidazole derivatives.

Definition

ChEBI: N-acetylimidazole is a N-acylimidazole.

General Description

Rate of solvolysis of 1-acetylimidazole in acid solutions was evaluated. Reaction of 1-acetylimidazole with orthophosphate and adenosine-5′-phosphate has been reported.

Purification Methods

It is recrystallised from isopropenyl acetate and dried in a vacuum over P2O5. [Riordan & Valee Methods Enzymol 25 500 1972, Beilstein 23/4 V 218.]

1-Acetylimidazole Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-Acetylimidazole Suppliers

Nanjing wangzhixing Pharmaceutical Technology Co., Ltd
Tel
15850510341
Fax
025-85722793
Email
shiqingran@wzxchem.com
Country
China
ProdList
3731
Advantage
58
Shanghai Scochem Technology Co., Ltd.
Tel
021-33758897
Email
sales@scochem.com
Country
China
ProdList
1596
Advantage
58
Hubei Xingyan New Material Technology Co., Ltd
Tel
13129948835
Email
2756772312@qq.com
Country
China
ProdList
5007
Advantage
58
Hubei Soren Technology Co., Ltd
Tel
0-13419562052 13419562052
Email
wwmlyb@163.com
Country
China
ProdList
2860
Advantage
58
SiChuang NanBu Honesty Technology Co., Ltd.
Tel
0838-5675166 15883665058
Fax
0838-5675535
Email
nbcxkj@126.com
Country
China
ProdList
667
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
INTATRADE GmbH
Tel
+49 3493/605464
Fax
+49 3493/605470
Email
sales@intatrade.de
Country
Germany
ProdList
3572
Advantage
66
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
More
Less

View Lastest Price from 1-Acetylimidazole manufacturers

HebeiShuoshengImportandExportco.,Ltd
Product
1-Acetylimidazole 2466-76-4
Price
US $6.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
2000KG/Month
Release date
2024-08-08
Hebei Longbang Technology Co., Ltd
Product
1-Acetylimidazole 2466-76-4
Price
US $6.00/kg
Min. Order
1kg
Purity
More than 99%
Supply Ability
2000KG/Month
Release date
2024-04-28
Hebei Jingbo New Material Technology Co., Ltd
Product
1-Acetylimidazole 2466-76-4
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
1000000
Release date
2023-12-21

2466-76-4, 1-AcetylimidazoleRelated Search:


  • 1-Acetylimidazole98%
  • N-Acetylimidazole,98%
  • N-ACETYLIMIDAZOL
  • N-ACETYLIMIDAZOLE extrapure AR
  • 1-Imidazolylmethyl ketone
  • 1-Imidazol-1-ylethanone
  • 1-(1H-Imidazole-1-yl)ethanone
  • 1-Acetylimidazole ,99%
  • 1-AcetliMidazole
  • 1-(1H-IMidazol-1-yl)ethanone
  • 1-Acetylimidazole Vetec(TM) reagent grade, 98%
  • 1-Acetylimidazole≥ 98% (Titration)
  • 1-acetyl-1h-imidazol
  • 1-Acetyl-1H-imidazole
  • 1-acetyl-imidazol
  • Acetylimidazole
  • Imidazole, 1-acetyl-
  • NAI
  • N-ACETYLIMIDAZOLE
  • 1-ACETYLIMIDAZOLE
  • 1-Acetylimidazole;N-Acetylimidazole;1-Imidazolylmethyl ketone
  • Ethanone,1-(1H-imidazol-1-yl)-
  • Ozagrel Impurity 4
  • TIMTEC-BB SBB008874
  • 4-ACETYLIMIDAZOLE
  • N-Acetylimidazole &gt
  • 1-(1H-imidazol-1-yl)ethan-1-one
  • 1-Acetylimidazole USP/EP/BP
  • 1-Acetylimida
  • 2466-76-4
  • Acylation (GC Derivatizing Reagents)
  • GC Derivatizing Reagents
  • BioChemical
  • Specific Amino Acid Modification
  • Proteomics and Protein Expression
  • Protein Modification
  • Proteomics
  • Reagents for tyrosine modification
  • amino
  • ImidazolesProtein Modification
  • Reagents for tyrosine modification
  • Building Blocks
  • Heterocyclic Building Blocks
  • Specific Amino Acid Modification
  • Acylation (GC Derivatizing Reagents)
  • GC Derivatizing Reagents
  • Analytical Chemistry
  • Imidazoles