Pharmacological effects
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Geniposide

Pharmacological effects
Product Name
Geniposide
CAS No.
24512-63-8
Chemical Name
Geniposide
Synonyms
Geniposidic;Genipin 1-glucoside;GENIPOSIDE;Geniposide>Geniposide(P);Geniposide-RM;Olea europaea L;Geniposide ,98%;Geniposide (8CI);TIANFU-CHEM Geniposide
CBNumber
CB9347733
Molecular Formula
C17H24O10
Formula Weight
388.37
MOL File
24512-63-8.mol
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Geniposide Property

Melting point:
160.0 to 164.0 °C
Boiling point:
641.4±55.0 °C(Predicted)
Density 
1.54±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
H2O: ≥5mg/mL
form 
powder
pka
12.80±0.70(Predicted)
color 
white to beige
Stability:
Hygroscopic
InChIKey
IBFYXTRXDNAPMM-BWBTYKGONA-N
SMILES
C12C(CO)=CCC1C(C(=O)OC)=CO[C@H]2O[C@H]1[C@H](O)[C@H]([C@H](O)[C@@H](CO)O1)O |&1:14,16,17,19,20,22,r|
LogP
-1.920 (est)
CAS DataBase Reference
24512-63-8(CAS DataBase Reference)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SML0153
Product name
Geniposide
Purity
≥98% (HPLC)
Packaging
10mg
Price
$228
Updated
2024/03/01
Sigma-Aldrich
Product number
SML0153
Product name
Geniposide
Purity
≥98% (HPLC)
Packaging
50mg
Price
$885
Updated
2024/03/01
TCI Chemical
Product number
G0385
Product name
Geniposide
Purity
>95.0%(HPLC)
Packaging
100mg
Price
$89
Updated
2024/03/01
TCI Chemical
Product number
G0385
Product name
Geniposide
Purity
>95.0%(HPLC)
Packaging
1g
Price
$370
Updated
2024/03/01
Cayman Chemical
Product number
28281
Product name
Geniposide
Packaging
100mg
Price
$61
Updated
2024/03/01
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Geniposide Chemical Properties,Usage,Production

Pharmacological effects

Geniposide, also known as Gardenia glycosides, geniposide. It is a brown to white crystalline powder, with little flavor and no bitter taste, a cycloolefin ether glycoside compound extracted from the dry and ripe fruit of Rubiaceae Gardenia. Geniposide has a significant role in promoting bile secretion, and can reduce blood bilirubin, as well as promote rapid excretion of bilirubin in the blood. It has an inhibitory effect on Streptococcus hemolyticus and skin fungi. It also has antipyretic, analgesic, sedative, antihypertensive and hemostatic effects. Geniposide has the function of purging pathogenic fire and eliminating restlessness, clearing heat and eliminating damp, decreasing swellinging to relieving pain. The Indications of Geniposide are heat disease, dysphoria, coma delirium, jaundice, heat stranguria, heat in blood, swelling and pain of eye, pathopyretic ulcer, and sprain.

Chemical Properties

White powder

Uses

Geniposide is an iridoid glycoside isolated from the fruit of Gardenia jasminoides Ellis. Geniposide is one of the biologically active ingredients of gardenia fruit. Geniposide is widely used in multi-component injection in the treatment of cerebrovascula

Definition

ChEBI: Geniposide is a terpene glycoside.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

Biochem/physiol Actions

Geniposide is an iridoid glycoside with a variety of biological activities including neuroprotective, anti-diabetic, antiproliferative, and antioxidative activity. Geniposide has been shown to regulate Nrf2 translocation and upregulate downstream antioxidant protein HO-1 expression through the PI3K/Akt signaling pathway, which may account for its neuroprotective and antioxidative activity. Glucagon-like peptide 1 (GLP-1) receptor may also play a critical role in geniposide induced HO-1 expression.

Geniposide Preparation Products And Raw materials

Raw materials

Preparation Products

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Geniposide Suppliers

BIOSYNTH AG
Tel
--
Fax
--
Email
welcome@biosynth.ch
Country
Switzerland
ProdList
1308
Advantage
60
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View Lastest Price from Geniposide manufacturers

Hovane Phytochemicals Co., Ltd
Product
Geniposide 24512-63-8
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%HPLC
Supply Ability
1 ton
Release date
2024-11-07
BINBO BIOLOGICAL CO.,LTD
Product
Geniposide 24512-63-8
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1000 kg
Release date
2024-04-26
Hebei Weibang Biotechnology Co., Ltd
Product
Geniposide 24512-63-8
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-10-31

24512-63-8, GeniposideRelated Search:


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  • Genipin 1-glucoside
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  • 24512-63-8
  • 24152-63-8
  • 24512-61-8
  • C17H24O10
  • Inhibitors
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
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  • Standard extract
  • Iridoids