Description
ChemicalBook > CAS DataBase List > 5-Chlorovaleryl chloride

5-Chlorovaleryl chloride

Description
Product Name
5-Chlorovaleryl chloride
CAS No.
1575-61-7
Chemical Name
5-Chlorovaleryl chloride
Synonyms
5-CHLOROPENTANOYL CHLORIDE;5-Chlorvalerylchlorid;5-CHLOROVALEROYL CHLORIDE;orovaL;5-Chlorovaleryl;Apixaban Impurity 56;5-chloro aMyl chloride;5 - chlorine e chloride;5-chloro-valerylchlorid;5-chlorvaleryl chloride
CBNumber
CB9348033
Molecular Formula
C5H8Cl2O
Formula Weight
155.02
MOL File
1575-61-7.mol
More
Less

5-Chlorovaleryl chloride Property

Boiling point:
38-39 °C0.15 mm Hg(lit.)
Density 
1.206 g/mL at 20 °C
refractive index 
n20/D 1.464(lit.)
Flash point:
195 °F
storage temp. 
Store below +30°C.
solubility 
Acetonitrile (Slightly), Chloroform (Sparingly)
form 
Liquid
color 
Clear colorless to slightly yellow
Specific Gravity
1.200
PH
<7 (H2O, 20℃)
explosive limit
2.0-10.2%(V)
Water Solubility 
reacts
Sensitive 
Moisture Sensitive
BRN 
1745182
Stability:
Corrosive, Moisture Sensitive
InChIKey
SVNNWKWHLOJLOK-UHFFFAOYSA-N
CAS DataBase Reference
1575-61-7(CAS DataBase Reference)
More
Less

Safety

Hazard Codes 
C,T
Risk Statements 
22-34-23-23/34
Safety Statements 
26-36/37/39-45
RIDADR 
UN 3265 8/PG 2
WGK Germany 
1
RTECS 
YV9108000
10-19-21
HazardClass 
8
PackingGroup 
III
HS Code 
29159000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H314Causes severe skin burns and eye damage

Precautionary statements

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
125245
Product name
5-Chlorovaleroyl chloride
Purity
96%
Packaging
10g
Price
$77.4
Updated
2024/03/01
Sigma-Aldrich
Product number
125245
Product name
5-Chlorovaleroyl chloride
Purity
96%
Packaging
50g
Price
$233.4
Updated
2024/03/01
TCI Chemical
Product number
C1789
Product name
5-Chlorovaleryl Chloride
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$41
Updated
2024/03/01
TCI Chemical
Product number
C1789
Product name
5-Chlorovaleryl Chloride
Purity
>98.0%(GC)(T)
Packaging
25g
Price
$116
Updated
2024/03/01
Alfa Aesar
Product number
H56237
Product name
5-Chlorovaleroyl chloride, 98%
Packaging
50g
Price
$262
Updated
2024/03/01
More
Less

5-Chlorovaleryl chloride Chemical Properties,Usage,Production

Description

5-Chlorovaleryl chloride is an important synthetic intermediate of pyrazole herbicides. 5-Chloropentanoyl chloride is used as the raw material of 1,1,7-trichloro-1-hepten-3-one, and then the third-generation pyrazole herbicides can be synthesized. Pyrazole herbicides have the characteristics of ultra-efficient herbicidal activity, high selectivity, extremely low mammalian toxicity and good environmental characteristics, and have become a hot spot in the research and development of herbicides in the world in recent years.

Chemical Properties

clear colourless to slightly yellow liquid

Uses

5-Chlorovaleroyl chloride (5-CVC) has been used in the development and validation of a GC-FID method for the analysis of low level impurities present in 5-CVC. It has been used in the synthesis of anion-exchange resins by acylation of polystyrene/divinylbenzene and subsequent amination with trimethylamine. It is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.

Application

5-Chlorovaleryl chloride is an important medicine and pesticide intermediate. It is pharmaceutically mainly for the manufacture of the medicine Cilostazole (Cilostazol) for anti-platelet aggregation, protection of vascular endothelial cells, and atherosclerosis.5-Chlorovaleryl Chloride is also for the production of paddy rice New-type wide-spectrum weedicide pyraclonil (Pyraclonil).

General Description

5-Chlorovaleroyl chloride is commonly used as alkylating agent in the synthesis of pharmaceutical intermediates and other specialty chemicals.

Flammability and Explosibility

Not classified

Synthesis

In the existing process, producing 5-Chlorovaleryl chloride using 1,4-dichlorobutane as raw material requires a three-step reaction. First, 1,4-dichlorobutane and sodium cyanide solution are combined to form 5-chlorovaleronitrile. Then, the prepared 5-chlorovaleronitrile is hydrolyzed in concentrated hydrochloric acid to form 5-chlorovaleric acid. Finally, 5-chlorovaleronitrile reacts with thionyl chloride to generate 5-chlorovaleryl chloride.

5-Chlorovaleryl chloride Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

5-Chlorovaleryl chloride Suppliers

UkrOrgSynthesis Ltd.
Tel
--
Fax
--
Email
y.barysheva@ukrorgsynth.com
Country
Ukraine
ProdList
6230
Advantage
38
CAS Organic Company
Tel
--
Fax
--
Email
Sales@casorganic.com
Country
Ukraine
ProdList
5026
Advantage
34
More
Less

View Lastest Price from 5-Chlorovaleryl chloride manufacturers

Speranza Chemical Co., Ltd.
Product
5-Chlorovaleryl chloride 1575-61-7
Price
US $20.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
300MT/year
Release date
2021-02-02
Hebei Yanxi Chemical Co., Ltd.
Product
5-Chlorovaleryl chloride 1575-61-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20 tons
Release date
2023-08-10
Henan Fengda Chemical Co., Ltd
Product
5-Chlorovaleryl chloride 1575-61-7
Price
US $6.00-0.60/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-01-18

1575-61-7, 5-Chlorovaleryl chlorideRelated Search:


  • 5-Chlorovaleryl
  • 5-CHLOROVALERYL CHLORIDE CVC
  • 5-Chlorvalerylchlorid
  • 5-Chlorovaleric acid chloride
  • 5-Chlorovaleryl chloride,96%
  • 5-chloro aMyl chloride
  • 5-Choropentanoyl chloride
  • 5-Chlorovaleryl chloride, 96% 10ML
  • 5-Chlorovaleryl chloride in stock Factory
  • orovaL
  • Apixaban Impurity 56
  • 5-chloro-pentanoylchlorid
  • 5-Chlorovaleroyl chloride, 98%+
  • 5 - chlorine e chloride
  • 5-Chlorovaleroyl chloride 96%
  • 5-Chlorovaleryl chloride for synthesis
  • 5-chloro-valerylchlorid
  • 5-CHLOROVALEROYL CHLORIDE
  • 5-CHLOROVALERYL CHLORIDE
  • 5-CHLOROPENTANOYL CHLORIDE
  • 5-CHLORO-N-VALEROYL CHLORIDE
  • DELTA-CHLOROVALEROYL CHLORIDE
  • D-CHLOROVALEROYL CHLORIDE
  • PENTANOYL CHLORIDE, 5-CHLORO-
  • 5-Chlorovaleryl Chloride &gt
  • RSYY(Vorapaxar Sulfatet)-46
  • RSYY(Vorapaxar Sulfatet)-48
  • 5-ChlorovaIeryl Chloride
  • 5-chlorvaleryl chloride
  • 5-chlorovelarylchloride
  • 1575-61-7
  • 1575-61-1
  • ClCH24COCl
  • Carbonyl Compounds
  • Acid Halides
  • Building Blocks
  • Organic Building Blocks
  • Miscellaneous Biochemicals
  • ACID CHLORIDES
  • fine chemicals
  • 1