1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Property

storage temp. 

−20°C

solubility 

DMF: > 20 mg/ml; DMSO: > 7 mg/ml; Ethanol: > 30 mg/ml; PBS (pH 7.2): > 250 μg/ml

form 

solution

color 

White to off-white

Safety

Hazard Codes 

Xn

Risk Statements 

22-38-40-48/20/22-36/38-20/22-63

Safety Statements 

36/37-26

RIDADR 

UN 1888 6.1/PG 3

WGK Germany 

3

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H331Toxic if inhaled

H336May cause drowsiness or dizziness

H351Suspected of causing cancer

H372Causes damage to organs through prolonged or repeated exposure

H412Harmful to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P308+P313IF exposed or concerned: Get medical advice/attention.

1,2-DIHEXANOYL-SN-GLYCERO-3-PHOSPHOCHOLINE Chemical Properties,Usage,Production

Description

1,2-Dihexanoyl-sn-glycero-3-PC (DHPC-C6) is a synthetic phospholipid containing the short-chain (6:0) caproic acid inserted at the sn-1 and sn-2 positions. It is a substrate for phospholipase C isolated from B. cereus as well as phospholipase A₂ isolated from A. halys blomhoffi and N. naja atra snake venom. DHPC is commonly used in the generation of micelles, liposomes, and other types of artificial membranes.

Uses

L-α-Dihexanoyllecithin is used in the targeted delivery of adamantylated peptidoglycan immunomodulators in lipid nanocarriers.

Definition

ChEBI: 1,2-dihexanoyl-sn-glycero-3-phosphocholine is a phosphatidylcholine 12:0 in which both acyl groups are specified as hexanoyl. It has a role as a surfactant. It is functionally related to a hexanoic acid.