1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE

Product Name: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE
CAS No.: 14150-94-8
Chemical Name: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE
Synonyms: 1-Methyl-3,5-dinitropyridin-2(1H)-one;1-Methyl-3,5-dinitro-2-pyridone;Atogepant Impurity 14;1-Methyl-3,5-dinitro-1H-p...;1-Methyl-3,5-dinitropyridine-2;3,5-Dinitro-1-methyl-2-pyridone;1-Methyl-3,5-dinitro-2-pyridine;1-Methyl-3,5-dinitro-2-pyridinone;1-METHYL-3,5-DINITROPYRIDIN-2-ONE;1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE
CBNumber: CB9352014
Molecular Formula: C6H5N3O5
Formula Weight: 199.12
MOL File: 14150-94-8.mol

More

Less

1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE Property

Melting point:: 174-178℃
Boiling point:: 289.5±40.0 °C(Predicted)
Density: 1.60
storage temp.: Store at 0-8℃
pka: -8.36±0.62(Predicted)
form: powder to crystal
color: Light orange to Yellow to Green
λmax: 308nm(H2O)(lit.)
InChI: InChI=1S/C6H5N3O5/c1-7-3-4(8(11)12)2-5(6(7)10)9(13)14/h2-3H,1H3
InChIKey: QARVELJVEBLWGK-UHFFFAOYSA-N
SMILES: C1(=O)N(C)C=C([N+]([O-])=O)C=C1[N+]([O-])=O

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HS Code: 2933399990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 680885
Product name: 1-Methyl-3,5-dinitropyridin-2(1H)-one
Purity: 97%
Packaging: 1g
Price: $83.2
Updated: 2023/06/20

TCI Chemical

Product number: M2820
Product name: 1-Methyl-3,5-dinitro-2-pyridone
Purity: >98.0%(GC)
Packaging: 1g
Price: $71
Updated: 2025/07/31

TRC

Product number: M218858
Product name: 1-Methyl-3,5-dinitro-1H-pyridin-2-one
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M218858
Product name: 1-Methyl-3,5-dinitro-1H-pyridin-2-one
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Usbiological

Product number: 284067
Product name: 1-Methyl-3,5-dinitro-1H-pyridin-2-one
Packaging: 500mg
Price: $333
Updated: 2021/12/16

More

Less

1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE Chemical Properties,Usage,Production

Uses

1-Methyl-3,5-dinitro-1H-pyridin-2-one can be used as an organic synthesis intermediate involved in the efficient synthesis of nitrocyclic ether[b]pyridine. It is also a nucleophilic reagent. It reacts with primary amines to produce carbamates in an efficient way without using reducing agents. The electronic defects of the pyridine cation allow this nucleophilic attack.

Synthesis

694-85-9

14150-94-8

General procedure for the synthesis of 1-methyl-3,5-dinitro-1H-pyridin-2-one from 1-methyl-2-pyridone: To a stirred mixture of 1-methyl-2-pyridone (33.47 g, 0.306 mol) and concentrated sulfuric acid (300 mL) was added concentrated nitric acid (120 mL) in batches at 100 °C. The reaction mixture was heated at this temperature overnight and then poured into ice (1400 mL). The precipitate was collected by filtration and washed with water to afford 1-methyl-3,5-dinitro-1H-pyridin-2-one (yield: 18.66 g, 30%).1H NMR (400 MHz, CDCl3): δ 9.05 (d, 1H), 8.90 (d, 1H), 3.80 (s, 3H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 20, p. 5392 - 5397
[2] Patent: WO2004/69832, 2004, A2. Location in patent: Page 137-138
[3] Patent: US2011/98311, 2011, A1
[4] Patent: US2012/309758, 2012, A1
[5] Patent: US2015/231142, 2015, A1. Location in patent: Paragraph 0698

1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE Suppliers

Americas 1 China 129 Europe 1 India 2 Japan 1 United Kingdom 1 United States 16 Global 151

Heze Aiding Pharmaceutical Co., Ltd

Tel: 17661365138
Email: 2845578351@qq.com
Country: China
ProdList: 7115
Advantage: 58

ChemFuture PharmaTech (Jiangsu) Ltd

Tel: 5108538618
Fax: 86 510 85386988-8017
Email: suger.wang@chemfuture.com
Country: China
ProdList: 832
Advantage: 65

Chembest Research Laboratories Limited

Tel: +86-21-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6003
Advantage: 61

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Pure Chemistry Scientific Inc.

Tel: 001-857-928-2050 or 1-888-588-9418
Fax: 001-617-206-9595
Email: sales@chemreagents.com
Country: United States
ProdList: 10186
Advantage: 62

Shanghai Longsheng chemical Co.,Ltd.

Tel: 021-58099652-8005 13585536065
Fax: 021-58099609
Email: bin.wu@shlschem.com
Country: China
ProdList: 9883
Advantage: 59

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32321
Advantage: 50

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

More

Less

View Lastest Price from 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE manufacturers

Hpets Biotech Company (Chongqing) Co.,ltd

Product: 1-Methyl-3,5-dinitropyridin-2(1H)-one 14150-94-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 tons
Release date: 2023-03-23

Honest Joy Holdings Limited

Product: 1-Methyl-3,5-dinitro-1H-pyridin-2-one 14150-94-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.9%
Supply Ability: 100 tons
Release date: 2022-01-26

Dideu Industries Group Limited

Product: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE 14150-94-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-26

14150-94-8, 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONERelated Search:

Pyridine Tosyl chloride 2-Cyanopyridine 3-Nitro-2-pyridinol 5-AMINO-1-METHYLPYRIDIN-2(1H)-ONE 2-HYDROXY-3,5-DINITROPYRIDINE 5-NITRO-1-METHYL-2(1H)-PYRIDINONE 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE

1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE

2(1H)-Pyridinone, 1-methyl-3,5-dinitro-

1-Methyl-3,5-dinitropyridin-2(1H)-one

1-Methyl-3,5-dinitro-1,2-dihydropyridine-2-one

3,5-Dinitro-1-methyl-2-pyridone

1-Methyl-3,5-dinitropyridine-2

1-Methyl-3,5-dinitro-1H-p...

1-Methyl-3,5-dinitropyridine-2(1H)-one

1-Methyl-3,5-dinitro-2-pyridone

1-Methyl-3,5-dinitro-1,2-dihydropyridin-2-one

1-Methyl-3,5-dinitropyridin-2(1H)-one

1-Methyl-3,5-dinitro-2-pyridinone

1-Methyl-3,5-dinitropyridin-2(1H)-one 97%

1-Methyl-3,5-dinitropyridin-2(1H)-one

1-METHYL-3,5-DINITROPYRIDIN-2-ONE

1-methyl-3,5-dinitro-2(1H)-Pyridinone

1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE ISO 9001：2015 REACH

1-Methyl-3,5-dinitro-2-pyridine

Atogepant Impurity 14

14150-94-8

Pyridines

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

Heterocycle-Pyridine series

C6