ChemicalBook > CAS DataBase List > 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE

1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE

Product Name: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE
CAS No.: 14150-94-8
Chemical Name: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE
Synonyms: 1-Methyl-3,5-dinitropyridin-2(1H)-one;1-Methyl-3,5-dinitro-2-pyridone;Atogepant Impurity 14;1-Methyl-3,5-dinitro-1H-p...;1-Methyl-3,5-dinitropyridine-2;3,5-Dinitro-1-methyl-2-pyridone;1-Methyl-3,5-dinitro-2-pyridine;1-Methyl-3,5-dinitro-2-pyridinone;1-METHYL-3,5-DINITROPYRIDIN-2-ONE;1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE
CBNumber: CB9352014
Molecular Formula: C6H5N3O5
Formula Weight: 199.12
MOL File: 14150-94-8.mol

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1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE Property

Melting point:: 174-178℃
Boiling point:: 289.5±40.0 °C(Predicted)
Density: 1.60
storage temp.: Store at 0-8℃
pka: -8.36±0.62(Predicted)
form: powder to crystal
color: Light orange to Yellow to Green
λmax: 308nm(H2O)(lit.)
InChI: InChI=1S/C6H5N3O5/c1-7-3-4(8(11)12)2-5(6(7)10)9(13)14/h2-3H,1H3
InChIKey: QARVELJVEBLWGK-UHFFFAOYSA-N
SMILES: C1(=O)N(C)C=C([N+]([O-])=O)C=C1[N+]([O-])=O

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HS Code: 2933399990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Warning
Hazard statements: H302Harmful if swallowed

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 680885
Product name: 1-Methyl-3,5-dinitropyridin-2(1H)-one
Purity: 97%
Packaging: 1g
Price: $83.2
Updated: 2023/06/20

TCI Chemical

Product number: M2820
Product name: 1-Methyl-3,5-dinitro-2-pyridone
Purity: >98.0%(GC)
Packaging: 1g
Price: $71
Updated: 2025/07/31

Usbiological

Product number: 284067
Product name: 1-Methyl-3,5-dinitro-1H-pyridin-2-one
Packaging: 500mg
Price: $333
Updated: 2021/12/16

TRC

Product number: M218858
Product name: 1-Methyl-3,5-dinitro-1H-pyridin-2-one
Packaging: 10mg
Price: $45
Updated: 2021/12/16

TRC

Product number: M218858
Product name: 1-Methyl-3,5-dinitro-1H-pyridin-2-one
Packaging: 50mg
Price: $60
Updated: 2021/12/16

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1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE Chemical Properties,Usage,Production

Uses

1-Methyl-3,5-dinitro-1H-pyridin-2-one can be used as an organic synthesis intermediate involved in the efficient synthesis of nitrocyclic ether[b]pyridine. It is also a nucleophilic reagent. It reacts with primary amines to produce carbamates in an efficient way without using reducing agents. The electronic defects of the pyridine cation allow this nucleophilic attack.

Synthesis

694-85-9

14150-94-8

General procedure for the synthesis of 1-methyl-3,5-dinitro-1H-pyridin-2-one from 1-methyl-2-pyridone: To a stirred mixture of 1-methyl-2-pyridone (33.47 g, 0.306 mol) and concentrated sulfuric acid (300 mL) was added concentrated nitric acid (120 mL) in batches at 100 °C. The reaction mixture was heated at this temperature overnight and then poured into ice (1400 mL). The precipitate was collected by filtration and washed with water to afford 1-methyl-3,5-dinitro-1H-pyridin-2-one (yield: 18.66 g, 30%).1H NMR (400 MHz, CDCl3): δ 9.05 (d, 1H), 8.90 (d, 1H), 3.80 (s, 3H).

References

[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 20, p. 5392 - 5397
[2] Patent: WO2004/69832, 2004, A2. Location in patent: Page 137-138
[3] Patent: US2011/98311, 2011, A1
[4] Patent: US2012/309758, 2012, A1
[5] Patent: US2015/231142, 2015, A1. Location in patent: Paragraph 0698

1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE Suppliers

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View Lastest Price from 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE manufacturers

Hpets Biotech Company (Chongqing) Co.,ltd

Product: 1-Methyl-3,5-dinitropyridin-2(1H)-one 14150-94-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100 tons
Release date: 2023-03-23

Honest Joy Holdings Limited

Product: 1-Methyl-3,5-dinitro-1H-pyridin-2-one 14150-94-8
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.9%
Supply Ability: 100 tons
Release date: 2022-01-26

Dideu Industries Group Limited

Product: 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE 14150-94-8
Price: US $1.10/g
Min. Order: 1g
Purity: 99.00%
Supply Ability: 100 Tons Min
Release date: 2021-10-26

14150-94-8, 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONERelated Search:

Pyridine Tosyl chloride 2-Cyanopyridine 3-Nitro-2-pyridinol 5-AMINO-1-METHYLPYRIDIN-2(1H)-ONE 2-HYDROXY-3,5-DINITROPYRIDINE 5-NITRO-1-METHYL-2(1H)-PYRIDINONE 1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE

1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE

2(1H)-Pyridinone, 1-methyl-3,5-dinitro-

1-Methyl-3,5-dinitropyridin-2(1H)-one

1-Methyl-3,5-dinitro-1,2-dihydropyridine-2-one

3,5-Dinitro-1-methyl-2-pyridone

1-Methyl-3,5-dinitropyridine-2

1-Methyl-3,5-dinitro-1H-p...

1-Methyl-3,5-dinitropyridine-2(1H)-one

1-Methyl-3,5-dinitro-2-pyridone

1-Methyl-3,5-dinitro-1,2-dihydropyridin-2-one

1-Methyl-3,5-dinitropyridin-2(1H)-one

1-Methyl-3,5-dinitro-2-pyridinone

1-Methyl-3,5-dinitropyridin-2(1H)-one 97%

1-Methyl-3,5-dinitropyridin-2(1H)-one

1-METHYL-3,5-DINITROPYRIDIN-2-ONE

1-methyl-3,5-dinitro-2(1H)-Pyridinone

1-METHYL-3,5-DINITRO-1H-PYRIDIN-2-ONE ISO 9001：2015 REACH

1-Methyl-3,5-dinitro-2-pyridine

Atogepant Impurity 14

14150-94-8

Pyridines

Building Blocks

Chemical Synthesis

Heterocyclic Building Blocks

Heterocycle-Pyridine series