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ChemicalBook > CAS DataBase List > Triethylamine trihydrofluoride

Triethylamine trihydrofluoride

Application
Product Name
Triethylamine trihydrofluoride
CAS No.
73602-61-6
Chemical Name
Triethylamine trihydrofluoride
Synonyms
HF;TEA.3HF;TRIETHYLAMINE TRIS(HYDROGEN FLUORIDE);TREAT-HF;trihydrofluoride;riethylamine trihydrofluoride;TRIETHYLAMINE TRISHYDROFLUORIDE;HYDROGEN FLUORIDE TRIETHYLAMINE;MEC-82;amine trihydrofL
CBNumber
CB9356360
Molecular Formula
C6H18F3N
Formula Weight
161.21
MOL File
73602-61-6.mol
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Triethylamine trihydrofluoride Property

Melting point:
-29--27°C
Boiling point:
70 °C15 mm Hg(lit.)
Density 
0.989 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.3915(lit.)
Flash point:
190 °F
storage temp. 
Store below +30°C.
solubility 
soluble in Chloroform, Hexane
form 
Liquid
Specific Gravity
0.989
color 
Clear yellow to brown
PH
3 (H2O, 20℃)(saturated aqueous solution)
Water Solubility 
soluble
Sensitive 
Hygroscopic
BRN 
5522945
Exposure limits
ACGIH: TWA 2.5 mg/m3
NIOSH: IDLH 250 mg/m3
CAS DataBase Reference
73602-61-6(CAS DataBase Reference)
EPA Substance Registry System
Ethanamine, N,N-diethyl-, trihydrofluoride (73602-61-6)
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Safety

Hazard Codes 
T+,T,C,Xi,F
Risk Statements 
26/27/28-35-36/37/38-20/21/22-11
Safety Statements 
26-36/37/39-45-7/9-36/37-36-61-29-16-3
RIDADR 
UN 3265 8/PG 2
WGK Germany 
3
Hazard Note 
Corrosive
TSCA 
Yes
HazardClass 
8
PackingGroup 
II
HS Code 
29211910
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.14371
Product name
Triethylamine trishydrofluoride
Purity
for synthesis
Packaging
2ml
Price
$25.6
Updated
2024/03/01
Sigma-Aldrich
Product number
344648
Product name
Triethylamine trihydrofluoride
Purity
98%
Packaging
5g
Price
$28.7
Updated
2024/03/01
Sigma-Aldrich
Product number
8.14371
Product name
Triethylamine trishydrofluoride
Purity
for synthesis
Packaging
10ml
Price
$79.2
Updated
2024/03/01
Sigma-Aldrich
Product number
344648
Product name
Triethylamine trihydrofluoride
Purity
98%
Packaging
1kg
Price
$1420
Updated
2024/03/01
TCI Chemical
Product number
T2022
Product name
Triethylamine Trihydrofluoride
Purity
>95.0%(T)
Packaging
10g
Price
$58
Updated
2024/03/01
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Triethylamine trihydrofluoride Chemical Properties,Usage,Production

Application

The t-butyldimethylsilyl (TBDMS) group is the most widely used 2'-OH protection in synthesis of oligoribonucleotides. The TBDMS-group became much used particularly after it was combined with phosphoroamidite methodology and was also the choice when H-phosphonate based RNA-synthesis was introduced. Removal of TBDMS-protection is most commonly done with 1 M tetrabutylammonium fluoride (TBAF) in tetrahydrofuran (THF). These conditions has proven efficient.

Chemical Properties

clear yellow liquid

Uses

Triethylamine trihydrofluoride acts as a mild and selective fluorinating agent used in the synthesis of acid fluorides and alkyl fluorides. It is also used in the synthesis of vicinal difluorides from epoxides, 3-fluoroazetidine. It is utilized as a selective reagent for the cleavage of O-silyl groups in carbohydrates, nucleotides and cyanohydrins. It is actively involved in the electrochemical fluorodeiodination of alkyl iodides and fluorodesilylation in beta-lactams.

Uses

Mild and selective reagent that has been used in the fluorination of a wide variety of compounds. For a review, see Aldrichimica Acta.

General Description

Triethylamine trihydrofluoride (TREAT-HF) is a mild and selective reagent for the fluorination of a wide variety of compounds.

Triethylamine trihydrofluoride Preparation Products And Raw materials

Raw materials

Preparation Products

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Triethylamine trihydrofluoride Suppliers

Clearsynth Labs Limited
Tel
+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
Advantage
58
TCI Chemicals (India) Pvt. Ltd.
Tel
--
Fax
--
Email
sales-in@tcichemicals.com
Country
India
ProdList
6768
Advantage
58
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
India
ProdList
6905
Advantage
58
Regal Remedies Ltd.
Tel
--
Fax
--
Email
sales@regalremedies.com
Country
India
ProdList
61
Advantage
58
Gujarat Fluorochemicals Limited
Tel
--
Fax
--
Country
India
ProdList
27
Advantage
58
BTTCO Overseas Pvt. Ltd.
Tel
--
Fax
--
Email
bttco@bttcogroup.com
Country
India
ProdList
37
Advantage
58
HiMedia Laboratories
Tel
--
Fax
--
Email
o@himedialabs.com
Country
India
ProdList
1841
Advantage
58
Anand Agencies
Tel
--
Fax
--
Email
en@gmail.com
Country
India
ProdList
2332
Advantage
58
Avra Synthesis Pvt Ltd
Tel
--
Fax
--
Email
info@avrasynthesis.com
Country
India
ProdList
1603
Advantage
30
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View Lastest Price from Triethylamine trihydrofluoride manufacturers

Hebei Mojin Biotechnology Co.,Ltd
Product
Triethylamine trihydrofluoride 73602-61-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-09-11
Shaanxi Dideu Medichem Co. Ltd
Product
Triethylamine trihydrofluoride 73602-61-6
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2024-07-14
Henan Aochuang Chemical Co.,Ltd.
Product
Triethylamine trihydrofluoride 73602-61-6
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1Ton
Release date
2022-10-08

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