IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER

ChemicalBook > CAS DataBase List > IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER

Product Name: IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
CAS No.: 39028-27-8
Chemical Name: IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER
Synonyms: SIA;SIA Crosslinker;NHS IODOACETATE;N-IodoacetoxysucciniMide;Succinimidyl iodoacetate;N-SUCCINIMIDYL IODOACETATE;SIA (succinimidyl iodoacetate);N-Succinimidyl Iodoacetate >N-SucciniMidyl iodoacetate(SIA);N-Succinimidyl Iodoacetate, 95+%
CBNumber: CB9364435
Molecular Formula: C6H6INO4
Formula Weight: 283.02
MOL File: 39028-27-8.mol

Less

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Property

Melting point:: 148°C
Boiling point:: 315.6±44.0 °C(Predicted)
Density: 2.11±0.1 g/cm3(Predicted)
storage temp.: -20°C
solubility: DMF: 50 mg/mL
form: powder
color: White to Off-White

Less

Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
HS Code: 29251900

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: I9760
Product name: Iodoacetic acid N-hydroxysuccinimide ester
Purity: powder
Packaging: 100mg
Price: $264
Updated: 2024/03/01

Sigma-Aldrich

Product number: I9760
Product name: Iodoacetic acid N-hydroxysuccinimide ester
Purity: powder
Packaging: 50mg
Price: $304
Updated: 2024/03/01

TCI Chemical

Product number: S0844
Product name: N-Succinimidyl Iodoacetate
Purity: >95.0%(N)
Packaging: 100mg
Price: $235
Updated: 2024/03/01

TRC

Product number: S690290
Product name: N-Succinimidyl Iodoacetate
Packaging: 50mg
Price: $80
Updated: 2021/12/16

Chem-Impex

Product number: 22998
Product name: Succinimidyliodoacetate,≥98%(HPLC)
Purity: ≥98%(HPLC)
Packaging: 250MG
Price: $122.3
Updated: 2021/12/16

Less

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Chemical Properties,Usage,Production

Description

SIA Crosslinker is a non-cleavable, water-soluble crosslinker containig an NHS ester and an iodine group. The NHS ester is reactive toward amines while the iodine reacts with thiol groups.

Chemical Properties

White Solid

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 1.5 Angstroms

Uses

forms water soluble carboxylate derivatives

Uses

A sulfhydryl and amino reactive heterobifunctional protein crosslinking reagent. Spacer Arm: 1.5 Angstroms

Biological Activity

SIA Crosslinker is a non-cleavable ADC linker that can be used to synthesize antibody drug conjugates (ADCs).

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Less

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER Suppliers

Canada 1 China 104 France 1 Germany 1 India 3 Japan 1 Switzerland 1 United Kingdom 7 United States 25 Global 144

Wuhan Brin Technology Co., Ltd.

Tel: 3456065315 13260619011
Email: 3456065315@qq.com
Country: China
ProdList: 1730
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40240
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

Suzhou Highfine Biotech Co., Ltd

Tel: 0512-68311833 13962195826
Fax: 0512-68417696
Email: wuhao@highfine.com
Country: China
ProdList: 498
Advantage: 75

Wuhan Chemwish Technology Co., Ltd

Tel: 86-027-67849912
Fax: 86-027-87531808
Email: sales@chemwish.com
Country: China
ProdList: 35906
Advantage: 56

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 18217
Advantage: 66

Nanjing Habo Medical Technology Co., Ltd.

Tel: 025-85760892 13376090521
Fax: 025-85766769
Email: sales@habotech.com
Country: China
ProdList: 996
Advantage: 60

Chemsky（shanghai）International Co.,Ltd.

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 32344
Advantage: 50

Shandong Xiya Chemical Co., Ltd

Tel: 13355009207 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18739
Advantage: 57

Daicel Chiral Technologies (China)CO.,LTD

Tel: 021-50460086-9 15921403865
Fax: +86-21-50462321
Email: han_yajun@dctc.daicel.com
Country: China
ProdList: 6854
Advantage: 65

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14443
Advantage: 57

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10269
Advantage: 58

Beijing HuaMeiHuLiBiological Chemical

Tel: 010-56205725
Fax: 010-65763397
Email: waley188@sohu.com
Country: China
ProdList: 12338
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22519
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 18521735133 18521732826;
Fax: 021-50323701
Email: market@aladdin-e.com
Country: China
ProdList: 25014
Advantage: 65

Hunan HuaTeng Pharmaceutical Co., Ltd.,

Tel: 400-8592883 15367835770
Fax: 0731-82251112
Email: viola@huatengsci.com
Country: China
ProdList: 5877
Advantage: 58

Shanghai Xingui Biotechnology Co., Ltd.

Tel: 17501653713 17501653715
Email: xingui2022@126.com
Country: China
ProdList: 10033
Advantage: 58

Nanjing Chalf-Pharm Technology Co., Ltd.

Tel: 025-57018978 18251899859
Fax: 025-57018008
Email: sales@chalf-pharm.com
Country: China
ProdList: 5943
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51471
Advantage: 80

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 27322
Advantage: 60

Chengdu Dianchun Technology Co., Ltd

Tel: 400-1166-196 18502815961
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 14623
Advantage: 60

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6357
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131981
Advantage: 58

Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
Fax: 010-60605840
Email: psaitong@jm-bio.com
Country: China
ProdList: 12308
Advantage: 58

Anhui kuer Bioengineering Co., Ltd

Tel: 0551-65171243 13810511747
Email: kuer@kuerhuaxue.com
Country: China
ProdList: 2997
Advantage: 55

JinJin Le Chemical Co., Ltd

Tel: 10106090
Email: jjlchem2@163.com
Country: China
ProdList: 9986
Advantage: 58

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 10007
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19806
Advantage: 60

Shanghai BaiShun Biological Technology Co., Ltd

Tel: 021-37581181
Fax: 021-57456066
Email: sales@chem-mall.com
Country: China
ProdList: 10335
Advantage: 58

Capot Chemical Co.,Ltd.

Tel: 571-85586718 +8613336195806
Fax: +86-571-85864795
Email: sales@capotchem.com
Country: China
ProdList: 29797
Advantage: 60

Aikon International Limited

Tel: 025-66113011 18112977050
Fax: (5)02557626880
Email: cb6@aikonchem.com
Country: China
ProdList: 15495
Advantage: 58

Rhawn Reagent

Tel: 400-400-1332688 18019345275
Fax: 400-133-2688
Email: amy@rhawn.cn
Country: China
ProdList: 15503
Advantage: 58

Shanghai Haohong Pharmaceutical Co., Ltd.

Tel: 400-8210725 18016230971
Fax: 021-58955996
Email: malulu@leyan.com
Country: China
ProdList: 24971
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6038 18902104717
Email: sales@heowns.com
Country: China
ProdList: 20532
Advantage: 60

SuZhou Medinoah Co.,LTD.

Tel: 0512-0512-69561983 13914027025
Fax: 0512-69561982
Email: he_qf@medinoah.com
Country: China
ProdList: 3394
Advantage: 58

Angel Pharmatech, Ltd.

Tel: 17317130613
Fax: QQ3358272972
Email: 3358272972@qq.com
Country: China
ProdList: 3242
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 400-400-400-9004166 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52712
Advantage: 58

Beijing OKA biological technology co., LTD

Tel: 010-010-62971590 18548936886
Fax: 010-62340519
Email: 3462612863@qq.com
Country: China
ProdList: 6912
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 13028896684
Email: sales@rrkchem.com
Country: China
ProdList: 55896
Advantage: 58

SHANDONG ZHI SHANG CHEMICAL CO.LTD

Tel: +86 18953170293
Fax: +86 0531-67809011
Email: sales@sdzschem.com
Country: China
ProdList: 2931
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23556
Advantage: 58

Hubei Ipure Biology Co., Ltd

Tel: +8613367258412
Fax: 18062427325
Email: ada@ipurechemical.com
Country: China
ProdList: 10326
Advantage: 58

CD Chemical Group Limited

Tel: +8615986615575
Fax: 0086-13651442114
Email: info@codchem.com
Country: China
ProdList: 20356
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: 571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: CHINA
ProdList: 52867
Advantage: 58

Baoji Guokang Bio-Technology Co., Ltd.

Tel: 0917-3909592 13892490616
Fax: 09173909592
Email: gksales1@gk-bio.com
Country: China
ProdList: 9335
Advantage: 58

Shanxi Xuanran Import and Export Trade Co., Ltd.

Tel: +8617735180244
Email: mike_yan@xuanranglobal.com
Country: CHINA
ProdList: 4022
Advantage: 58

HONG KONG IPURE BIOLOGY CO.,LIMITED

Tel: 86 18062405514 18062405514
Email: ada@ipurechemical.com
Country: CHINA
ProdList: 3465
Advantage: 58

Less

View Lastest Price from IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER manufacturers

Zhuozhou Wenxi import and Export Co., Ltd

Product: IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER 39028-27-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

Zhuozhou Wenxi import and Export Co., Ltd

Product: IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER 39028-27-8
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-08

Career Henan Chemical Co

Product: IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER 39028-27-8
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2019-12-26

39028-27-8, IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTERRelated Search:

N-succinimidyl-4-((iodoacetyl)amino)benzoate N-Succinimidyl 4-(4-maleimidophenyl)butyrate TARTRONIC ACID 4'-Hydroxyacetophenone 2,5-dioxopyrrolidin-1-yl pent-4-ynoate Alkyne NHS ester (hexynoic acid NHS ester) 2,5-dioxopyrrolidin-1-yl 4-ethynylbenzoate 2,5-dioxopyrrolidin-1-yl 3-ethynylbenzoate Iodoacetic acid DISUCCINIMIDYL SUCCINATE 2-Iodoethanol DISULFOSUCCINIMIDYL-L-TARTRATE IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER

N-HydroxysucciniMide Iodoacetic Acid Ester

N-IodoacetoxysucciniMide

Iodoacetic Acid N-Succinimidyl Ester N-(Iodoacetoxy)succinimide

2,5-Pyrrolidinedione, 1-[(iodoacetyl)oxy]-

N-SucciniMidyl iodoacetate(SIA)

SIA

N-HYDROXYSUCCINIMIDYL IODOACETATE

NHS IODOACETATE

N-SUCCINIMIDYL IODOACETATE

SIA Crosslinker

Iodoacetic acid N-hydroxysuccinimide ester powder

2,5-Dioxopyrrolidin-1-yl 2-iodoacetate

IODOACETIC ACID N-HYDROXYSUCCINIMIDE ESTER

Succinimidyl iodoacetate

SIA (succinimidyl iodoacetate)

2-Iodoacetate N-Succinimidyl Ester

N-Succinimidyl Iodoacetate &gt

Acetic acid, 2-iodo-, 2,5-dioxo-1-pyrrolidinyl ester

Iodoacetic Acid N-Succinimidyl Ester

N-Succinimidyl Iodoacetate, 95+%

39028-27-8

C6H6INO4

C6H6NO4I

BioChemical

Crosslinking

Heterobifunctional Cross-Linking Reagents

Proteomics and Protein Expression

Protein Modification

Proteomics

MTS and Sulfhydryl Active Reagents

Heterobifunctional Crosslinker

heteroXlink

Cross Linking Reagents

MTS & Sulfhydryl Active Reagents

Active Esters/AdditivesProtein Modification

Active Esters/AdditivesSynthetic Reagents

Coupling

Crosslinking

Heterobifunctional Cross-Linking Reagents

Peptide Synthesis